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Inhibition of Pro-Apoptotic BAX by a Noncanonical Interaction Mechanism

Molecular cell, 2015-03, Vol.57 (5), p.873-886

2015

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An Autoinhibited Dimeric Form of BAX Regulates the BAX Activation Pathway

Molecular cell, 2016-08, Vol.63 (3), p.485-497

2016

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Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives

Nature chemical biology, 2013-06, Vol.9 (6), p.374

2013

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Eltrombopag directly inhibits BAX and prevents cell death

Nature communications, 2021-02, Vol.12 (1), p.1134-15, Article 1134

2021

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Modulating mitofusins to control mitochondrial function and signaling

Nature communications, 2022-07, Vol.13 (1), p.3775-3775, Article 3775

2022

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Targeting retinoic acid receptor alpha-corepressor interaction activates chaperone-mediated autophagy and protects against retinal degeneration

Nature communications, 2022-07, Vol.13 (1), p.4220-4220, Article 4220

2022

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Rumi functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase

Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (40), p.16600-16605

2011

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An Autoinhibited Dimeric Form of BAX Regulates the BAX Activation Pathway

Molecular cell, 2016-10, Vol.64 (2), p.431-431

2016

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A Kazal-Type Serine Protease Inhibitor from the Defense Gland Secretion of the Subterranean Termite Coptotermes formosanus Shiraki

PloS one, 2015-05, Vol.10 (5), p.e0125376-e0125376

2015

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Impact of p62/SQSTM1 UBA Domain Mutations Linked to Paget’s Disease of Bone on Ubiquitin Recognition

Biochemistry (Easton), 2011-05, Vol.50 (21), p.4665-4674

2011

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Small-molecule allosteric inhibitors of BAX

Nature chemical biology, 2019-04, Vol.15 (4), p.322

2019

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Progress in targeting the BCL-2 family of proteins

Current opinion in chemical biology, 2017-08, Vol.39, p.133-142

2017

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Independent Interactions of Ubiquitin-Binding Domains in a Ubiquitin-Mediated Ternary Complex

Biochemistry (Easton), 2011-10, Vol.50 (42), p.9076-9087

2011

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Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia

Cancer cell, 2017-10, Vol.32 (4), p.490-505.e10

2017

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Structural insights into specificity and diversity in mechanisms of ubiquitin recognition by ubiquitin-binding domains

Biochemical Society transactions, 2012-04, Vol.40 (2), p.404

2012

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Selectivity of small molecule ligands for parallel and anti-parallel DNA G-quadruplex structures

Organic & biomolecular chemistry, 2009-01, Vol.7 (20), p.4194-4200

2009

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Marinopyrrole derivatives with sulfide spacers as selective disruptors of Mcl-1 binding to pro-apoptotic protein Bim

Marine drugs, 2014-07, Vol.12 (8), p.4311-4325

2014

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Telomestatin: Formal Total Synthesis and Cation-Mediated Interaction of Its seco-Derivatives with G-Quadruplexes

Journal of the American Chemical Society, 2011-02, Vol.133 (4), p.1044-1051

2011

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Design, synthesis and evaluation of marinopyrrole derivatives as selective inhibitors of Mcl-1 binding to pro-apoptotic Bim and dual Mcl-1/Bcl-xL inhibitors

European journal of medicinal chemistry, 2015-01, Vol.90, p.315-331

2015

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Insights into the Molecular Composition of Endogenous Unanchored Polyubiquitin Chains

Journal of proteome research, 2012-03, Vol.11 (3), p.1969-1980

2012

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Occurrence of a Quadruplex Motif in a Unique Insert within Exon C of the Bovine Estrogen Receptor α Gene (ESR1)

Biochemistry (Easton), 2010-09, Vol.49 (35), p.7625-7633

2010

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On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium salts

Journal of experimental & clinical cancer research, 2013-09, Vol.32 (1), p.68-68, Article 68

2013

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Folding Topology of a Bimolecular DNA Quadruplex Containing a Stable Mini-hairpin Motif within the Diagonal Loop

Journal of molecular biology, 2009-02, Vol.385 (5), p.1600-1615

2009

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Mutant p62/SQSTM1 UBA domains linked to Paget’s disease of bone differ in their abilities to function as stabilization signals

FEBS letters, 2010-04, Vol.584 (8), p.1585-1590

2010

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Inhibition of Pro-Apoptotic BAX by a Noncanonical Interaction Mechanism

An Autoinhibited Dimeric Form of BAX Regulates the BAX Activation Pathway

Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives

Eltrombopag directly inhibits BAX and prevents cell death

Modulating mitofusins to control mitochondrial function and signaling

Targeting retinoic acid receptor alpha-corepressor interaction activates chaperone-mediated autophagy and protects against retinal degeneration

Rumi functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase

An Autoinhibited Dimeric Form of BAX Regulates the BAX Activation Pathway

A Kazal-Type Serine Protease Inhibitor from the Defense Gland Secretion of the Subterranean Termite Coptotermes formosanus Shiraki

Impact of p62/SQSTM1 UBA Domain Mutations Linked to Paget’s Disease of Bone on Ubiquitin Recognition

Small-molecule allosteric inhibitors of BAX

Progress in targeting the BCL-2 family of proteins

Independent Interactions of Ubiquitin-Binding Domains in a Ubiquitin-Mediated Ternary Complex

Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia

Structural insights into specificity and diversity in mechanisms of ubiquitin recognition by ubiquitin-binding domains

Selectivity of small molecule ligands for parallel and anti-parallel DNA G-quadruplex structures

Marinopyrrole derivatives with sulfide spacers as selective disruptors of Mcl-1 binding to pro-apoptotic protein Bim

A small-molecule allosteric inhibitor of BAX protects against doxorubicin-induced cardiomyopathy

Telomestatin: Formal Total Synthesis and Cation-Mediated Interaction of Its seco-Derivatives with G-Quadruplexes

Design, synthesis and evaluation of marinopyrrole derivatives as selective inhibitors of Mcl-1 binding to pro-apoptotic Bim and dual Mcl-1/Bcl-xL inhibitors

Insights into the Molecular Composition of Endogenous Unanchored Polyubiquitin Chains

Occurrence of a Quadruplex Motif in a Unique Insert within Exon C of the Bovine Estrogen Receptor α Gene (ESR1)

On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium salts

Folding Topology of a Bimolecular DNA Quadruplex Containing a Stable Mini-hairpin Motif within the Diagonal Loop

Mutant p62/SQSTM1 UBA domains linked to Paget’s disease of bone differ in their abilities to function as stabilization signals

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