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Inhibition of Prolyl Hydroxylases Increases Erythropoietin Production in ESRD

Journal of the American Society of Nephrology, 2010-12, Vol.21 (12), p.2151-2156

2010

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Catalytic Properties of the Asparaginyl Hydroxylase (FIH) in the Oxygen Sensing Pathway Are Distinct from Those of Its Prolyl 4-Hydroxylases

The Journal of biological chemistry, 2004-03, Vol.279 (11), p.9899-9904

2004

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Mouse Model for Noninvasive Imaging of HIF Prolyl Hydroxylase Activity: Assessment of an Oral Agent That Stimulates Erythropoietin Production

Proceedings of the National Academy of Sciences - PNAS, 2006-01, Vol.103 (1), p.105-110

2006

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Biochemical Purification and Pharmacological Inhibition of a Mammalian Prolyl Hydroxylase Acting on Hypoxia-Inducible Factor

Proceedings of the National Academy of Sciences - PNAS, 2002-10, Vol.99 (21), p.13459-13464

2002

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Activation of Hypoxia-Inducible Factors in Hyperoxia through Prolyl 4-Hydroxylase Blockade in Cells and Explants of Primate Lung

Proceedings of the National Academy of Sciences - PNAS, 2005-07, Vol.102 (29), p.10212-10217

2005

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Preconditional activation of hypoxia-inducible factors ameliorates ischemic acute renal failure

Journal of the American Society of Nephrology, 2006-07, Vol.17 (7), p.1970-1978

2006

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Characterization of the Human Prolyl 4-Hydroxylases That Modify the Hypoxia-inducible Factor

The Journal of biological chemistry, 2003-08, Vol.278 (33), p.30772-30780

2003

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Selective inhibition of hepatic collagen accumulation in experimental liver fibrosis in rats by a new prolyl 4‐hydroxylase inhibitor

Hepatology (Baltimore, Md.), 1998-08, Vol.28 (2), p.404-411

1998

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Stimulation of HIF-1α, HIF-2α, and VEGF by prolyl 4-hydroxylase inhibition in human lung endothelial and epithelial cells

Free radical biology & medicine, 2005-04, Vol.38 (8), p.1002-1013

2005

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Assay for 2-oxoglutarate decarboxylating enzymes based on the determination of [1- 14C]succinate: Application to prolyl 4-hydroxylase

Analytical biochemistry, 1990-02, Vol.184 (2), p.291-297

1990

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Inhibition of prolyl 4-hydroxylase prevents left ventricular remodelling in rats with thoracic aortic banding

European journal of heart failure, 2007-04, Vol.9 (4), p.336-342

2007

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Thalidomide in human immunodeficiency virus (HIV) patients : a review of safety considerations

Drug safety, 1992-03, Vol.7 (2), p.116-134

GÜNZLER, V

1992

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Hepatic fibrosis in rats produced by carbon tetrachloride and dimethylnitrosamine: Observations suggesting immunoassays of serum for the 75 fragment of type IV collagen are a more sensitive index of liver damage than immunoassays for the NH2‐terminal propeptide of type III procollagen

Hepatology (Baltimore, Md.), 1992-07, Vol.16 (1), p.167-172

1992

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Hypoxia-inducible factor prolyl 4-hydroxylase inhibition. A target for neuroprotection in the central nervous system

The Journal of biological chemistry, 2005-12, Vol.280 (50), p.41732-41743

2005

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Hypoxia-inducible Factor Prolyl 4-Hydroxylase Inhibition

The Journal of biological chemistry, , Vol.280 (50), p.41732-41743

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Stimulation of HIF-1alpha, HIF-2alpha, and VEGF by prolyl 4-hydroxylase inhibition in human lung endothelial and epithelial cells

Free radical biology & medicine, 2005-04, Vol.38 (8), p.1002-1013

2005

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Immunisation of Chickens with the Aminoterminal Propeptide of Bovine Procollagen Type III (Specificity of egg yolk antibodies and comparison with immunoassays using rabbit and mouse antibodies

ALTEX, alternatives to animal experimentation, 1996, Vol.13 (5), p.51-56

1996

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Prolyl hydroxylase activity in tissue homogenates of annelids from deep sea hydrothermal vents

Matrix biology, 1998-07, Vol.17 (3), p.205-212

1998

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Inhibition of Human Prolyl Hydroxylase as Common Biochemical Denominator of the Non-Sedative Effects of Thalidomide in Man

Zeitschrift für Naturforschung C. A journal of biosciences, 1977-04, Vol.32 (3), p.241-248

1977

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The bradykinin B 2 receptor antagonist Icatibant (HOE 140) corrects avid Na + retention in rats with CCl 4-induced liver cirrhosis: possible role of enhanced microvascular leakage

European journal of pharmacology, 1997, Vol.337 (1), p.45-53

1997

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Suppression of Immunopathology in Schistosomiasis by Interleukin-2-Targeted Fusion Toxin, DAB389IL-2 I. Studies ofin Vitroandin VivoEfficacy

Cellular immunology, 1995-12, Vol.166 (2), p.217-226

1995

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The bradykinin B2 receptor antagonist Icatibant (HOE 140) corrects avid Na+ retention in rats with CCl4-induced liver cirrhosis: possible role of enhanced microvascular leakage

European journal of pharmacology, 1997-10, Vol.337 (1), p.45-53

1997

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Specific inactivation of prolyl 4-hydroxylase and inhibition of collagen synthesis by oxaproline-containing peptides in cultured human skin fibroblasts

The Journal of biological chemistry, 1990-05, Vol.265 (15), p.8415-8419

1990

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The 2-oxoglutarate binding site of prolyl 4-hydroxylase: identification of distinct subsites and evidence for 2-oxoglutarate decarboxylation in a ligand reaction at the enzyme-bound ferrous ion

European journal of biochemistry, 1984-01, Vol.138 (2), p.239-245

1984

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Transglutaminase and polyamine dependence of effector functions of human immunocompetent cells

FEBS letters, 1982-12, Vol.150 (2), p.390-396

1982

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Inhibition of Prolyl Hydroxylases Increases Erythropoietin Production in ESRD

Catalytic Properties of the Asparaginyl Hydroxylase (FIH) in the Oxygen Sensing Pathway Are Distinct from Those of Its Prolyl 4-Hydroxylases

Mouse Model for Noninvasive Imaging of HIF Prolyl Hydroxylase Activity: Assessment of an Oral Agent That Stimulates Erythropoietin Production

Biochemical Purification and Pharmacological Inhibition of a Mammalian Prolyl Hydroxylase Acting on Hypoxia-Inducible Factor

Activation of Hypoxia-Inducible Factors in Hyperoxia through Prolyl 4-Hydroxylase Blockade in Cells and Explants of Primate Lung

Preconditional activation of hypoxia-inducible factors ameliorates ischemic acute renal failure

Characterization of the Human Prolyl 4-Hydroxylases That Modify the Hypoxia-inducible Factor

Selective inhibition of hepatic collagen accumulation in experimental liver fibrosis in rats by a new prolyl 4‐hydroxylase inhibitor

Stimulation of HIF-1α, HIF-2α, and VEGF by prolyl 4-hydroxylase inhibition in human lung endothelial and epithelial cells

Assay for 2-oxoglutarate decarboxylating enzymes based on the determination of [1- 14C]succinate: Application to prolyl 4-hydroxylase

Inhibition of prolyl 4-hydroxylase prevents left ventricular remodelling in rats with thoracic aortic banding

Thalidomide in human immunodeficiency virus (HIV) patients : a review of safety considerations

Hepatic fibrosis in rats produced by carbon tetrachloride and dimethylnitrosamine: Observations suggesting immunoassays of serum for the 75 fragment of type IV collagen are a more sensitive index of liver damage than immunoassays for the NH2‐terminal propeptide of type III procollagen

Hypoxia-inducible factor prolyl 4-hydroxylase inhibition. A target for neuroprotection in the central nervous system

Hypoxia-inducible Factor Prolyl 4-Hydroxylase Inhibition

Stimulation of HIF-1alpha, HIF-2alpha, and VEGF by prolyl 4-hydroxylase inhibition in human lung endothelial and epithelial cells

Immunisation of Chickens with the Aminoterminal Propeptide of Bovine Procollagen Type III (Specificity of egg yolk antibodies and comparison with immunoassays using rabbit and mouse antibodies

Prolyl hydroxylase activity in tissue homogenates of annelids from deep sea hydrothermal vents

Inhibition of Human Prolyl Hydroxylase as Common Biochemical Denominator of the Non-Sedative Effects of Thalidomide in Man

The bradykinin B 2 receptor antagonist Icatibant (HOE 140) corrects avid Na + retention in rats with CCl 4-induced liver cirrhosis: possible role of enhanced microvascular leakage

Suppression of Immunopathology in Schistosomiasis by Interleukin-2-Targeted Fusion Toxin, DAB389IL-2 I. Studies ofin Vitroandin VivoEfficacy

The bradykinin B2 receptor antagonist Icatibant (HOE 140) corrects avid Na+ retention in rats with CCl4-induced liver cirrhosis: possible role of enhanced microvascular leakage

Specific inactivation of prolyl 4-hydroxylase and inhibition of collagen synthesis by oxaproline-containing peptides in cultured human skin fibroblasts

The 2-oxoglutarate binding site of prolyl 4-hydroxylase: identification of distinct subsites and evidence for 2-oxoglutarate decarboxylation in a ligand reaction at the enzyme-bound ferrous ion

Transglutaminase and polyamine dependence of effector functions of human immunocompetent cells

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