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An Alphavirus -derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates

Science translational medicine, 2020-08, Vol.12 (555)

2020

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Preparing for Pandemics: RNA Vaccines at the Forefront

Molecular therapy, 2020-07, Vol.28 (7), p.1559-1560

2020

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Effects of therapeutic vaccination on the control of SIV in rhesus macaques with variable responsiveness to antiretroviral drugs

PloS one, 2021-06, Vol.16 (6), p.e0253265-e0253265

2021

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Early cellular innate immune responses drive Zika viral persistence and tissue tropism in pigtail macaques

Nature communications, 2018-08, Vol.9 (1), p.3371-11, Article 3371

2018

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Multigenic DNA vaccine induces protective cross-reactive T cell responses against heterologous influenza virus in nonhuman primates

PloS one, 2017-12, Vol.12 (12), p.e0189780-e0189780

2017

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A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response

PLoS pathogens, 2016-02, Vol.12 (2), p.e1005409-e1005409

2016

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Sustained AAV9-mediated expression of a non-self protein in the CNS of non-human primates after immunomodulation

PloS one, 2018-06, Vol.13 (6), p.e0198154-e0198154

2018

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STING Is Required in Conventional Dendritic Cells for DNA Vaccine Induction of Type I T Helper Cell- Dependent Antibody Responses

Frontiers in immunology, 2022-04, Vol.13, p.861710-861710

2022

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Efficient ex vivo expansion of conserved element vaccine-specific CD8+ T-cells from SHIV-infected, ART-suppressed nonhuman primates

Frontiers in immunology, 2023-05, Vol.14, p.1188018-1188018

2023

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Therapeutic conserved elements (CE) DNA vaccine induces strong T-cell responses against highly conserved viral sequences during simian-human immunodeficiency virus infection

Human vaccines & immunotherapeutics, 2018-07, Vol.14 (7), p.1820-1831

2018

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Replicating RNA platform enables rapid response to the SARS-CoV-2 Omicron variant and elicits enhanced protection in naïve hamsters compared to ancestral vaccine

EBioMedicine, 2022-09, Vol.83, p.104196-104196, Article 104196

2022

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Laparoscopic Technique for Serial Collection of Para-Colonic, Left Colic, and Inferior Mesenteric Lymph Nodes in Macaques

PloS one, 2016-06, Vol.11 (6), p.e0157535-e0157535

2016

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Correction: Sustained AAV9-mediated expression of a non-self protein in the CNS of non-human primates after immunomodulation

PloS one, 2018-11, Vol.13 (11), p.e0207077-e0207077

2018

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Correction: Laparoscopic Technique for Serial Collection of Para-Colonic, Left Colic, and Inferior Mesenteric Lymph Nodes in Macaques

PloS one, 2018-01, Vol.13 (1), p.e0190764-e0190764

2018

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Therapeutic DNA vaccine induces broad T cell responses in the gut and sustained protection from viral rebound and AIDS in SIV-infected rhesus macaques

PloS one, 2012-03, Vol.7 (3), p.e33715-e33715

2012

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Prospects for developing an effective particle-mediated DNA vaccine against influenza

Expert review of vaccines, 2009-09, Vol.8 (9), p.1205-1220

2009

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Induction of Mucosal Protection against Primary, Heterologous Simian Immunodeficiency Virus by a DNA Vaccine

Journal of Virology, 2002-04, Vol.76 (7), p.3309-3317

2002

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Computationally engineered influenza antiviral affords broad prophylactic and therapeutic protection against influenza

Journal of Virus Eradication, 2016-05, Vol.2, p.8-8

2016

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Commentary: HIV Vaccine Trial Exploits a Dual and Central Role for Innate Immunity

Journal of virology, 2014-10, Vol.88 (20), p.11640-11643

2014

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A computationally designed hemagglutinin stem-binding protein provides in vivo protection from influenza in the ferret model

The Journal of immunology (1950), 2016-05, Vol.196 (1_Supplement), p.145-145.17

2016

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A qualitative progression in HIV type 1 glycoprotein 120-specific cytotoxic cellular and humoral immune responses in mice receiving a DNA-based glycoprotein 120 vaccine

AIDS research and human retroviruses, 1994-11, Vol.10 (11), p.1433-1441

1994

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An Alphavirus -derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates

Preparing for Pandemics: RNA Vaccines at the Forefront

Effects of therapeutic vaccination on the control of SIV in rhesus macaques with variable responsiveness to antiretroviral drugs

Early cellular innate immune responses drive Zika viral persistence and tissue tropism in pigtail macaques

SARS-CoV2 variant-specific replicating RNA vaccines protect from disease following challenge with heterologous variants of concern

A replicon RNA vaccine can induce durable protective immunity from SARS-CoV-2 in nonhuman primates after neutralizing antibodies have waned

Multigenic DNA vaccine induces protective cross-reactive T cell responses against heterologous influenza virus in nonhuman primates

A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response

Sustained AAV9-mediated expression of a non-self protein in the CNS of non-human primates after immunomodulation

STING Is Required in Conventional Dendritic Cells for DNA Vaccine Induction of Type I T Helper Cell- Dependent Antibody Responses

Efficient ex vivo expansion of conserved element vaccine-specific CD8+ T-cells from SHIV-infected, ART-suppressed nonhuman primates

Therapeutic conserved elements (CE) DNA vaccine induces strong T-cell responses against highly conserved viral sequences during simian-human immunodeficiency virus infection

Replicating RNA platform enables rapid response to the SARS-CoV-2 Omicron variant and elicits enhanced protection in naïve hamsters compared to ancestral vaccine

Laparoscopic Technique for Serial Collection of Para-Colonic, Left Colic, and Inferior Mesenteric Lymph Nodes in Macaques

Correction: Sustained AAV9-mediated expression of a non-self protein in the CNS of non-human primates after immunomodulation

Correction: Laparoscopic Technique for Serial Collection of Para-Colonic, Left Colic, and Inferior Mesenteric Lymph Nodes in Macaques

Therapeutic DNA vaccine induces broad T cell responses in the gut and sustained protection from viral rebound and AIDS in SIV-infected rhesus macaques

A Gut Reaction to SIV and SHIV Infection: Lower Dysregulation of Mucosal T Cells during Acute Infection Is Associated with Greater Viral Suppression during cART

Induction of antigen-specific CD8+ T cells, T helper cells, and protective levels of antibody in humans by particle-mediated administration of a hepatitis B virus DNA vaccine

Prospects for developing an effective particle-mediated DNA vaccine against influenza

Induction of Mucosal Protection against Primary, Heterologous Simian Immunodeficiency Virus by a DNA Vaccine

Computationally engineered influenza antiviral affords broad prophylactic and therapeutic protection against influenza

Commentary: HIV Vaccine Trial Exploits a Dual and Central Role for Innate Immunity

A computationally designed hemagglutinin stem-binding protein provides in vivo protection from influenza in the ferret model

A qualitative progression in HIV type 1 glycoprotein 120-specific cytotoxic cellular and humoral immune responses in mice receiving a DNA-based glycoprotein 120 vaccine

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