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The challenges and promise of targeting the Liver X Receptors for treatment of inflammatory disease

Pharmacology & therapeutics (Oxford), 2018-01, Vol.181, p.1-12

Fessler, Michael B

2018

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Macrophage polarization in innate immune responses contributing to pathogenesis of chronic kidney disease

BMC nephrology, 2020-07, Vol.21 (1), p.270-13, Article 270

2020

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CD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation

Nature communications, 2021-08, Vol.12 (1), p.5029-5029, Article 5029

2021

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Myeloid Deletion of SIRT1 Induces Inflammatory Signaling in Response to Environmental Stress

Molecular and Cellular Biology, 2010-10, Vol.30 (19), p.4712-4721

2010

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The Toll-like receptor gene family is integrated into human DNA damage and p53 networks

PLoS genetics, 2011-03, Vol.7 (3), p.e1001360

2011

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Macrophage ABCA1 reduces MyD88-dependent Toll-like receptor trafficking to lipid rafts by reduction of lipid raft cholesterol[S]

Journal of lipid research, 2010-11, Vol.51 (11), p.3196-3206

2010

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Cholesterol biosynthesis modulates differentiation in murine cranial neural crest cells

Scientific reports, 2023-05, Vol.13 (1), p.7073-7073, Article 7073

2023

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IRGM1 supports host defense against intracellular bacteria through suppression of type I interferon in mice

The Journal of clinical investigation, 2023-11, Vol.133 (21), p.1-3

2023

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Race-specific association of an IRGM risk allele with cytokine expression in human subjects

Scientific reports, 2023-08, Vol.13 (1), p.12911-12911, Article 12911

2023

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Comparative and network-based proteomic analysis of low dose ethanol- and lipopolysaccharide-induced macrophages

PloS one, 2018-02, Vol.13 (2), p.e0193104

2018

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Implementing machine learning methods with complex survey data: Lessons learned on the impacts of accounting sampling weights in gradient boosting

PloS one, 2023-01, Vol.18 (1), p.e0280387

2023

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The Intracellular Cholesterol Landscape: Dynamic Integrator of the Immune Response

Trends in immunology, 2016-12, Vol.37 (12), p.819-830

Fessler, Michael B

2016

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Toll-like receptor signaling links dietary fatty acids to the metabolic syndrome

Current opinion in lipidology, 2009-10, Vol.20 (5), p.379-385

2009

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Cross-linking Proteomics Indicates Effects of Simvastatin on the TLR2 Interactome and Reveals ACTR1A as a Novel Regulator of the TLR2 Signal Cascade[S]

Molecular & cellular proteomics, 2019-09, Vol.18 (9), p.1732-1744

2019

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Mechanisms of neutrophil accumulation in the lungs against bacteria

American journal of respiratory cell and molecular biology, 2010-07, Vol.43 (1), p.5-16

2010

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APOε4 is associated with enhanced in vivo innate immune responses in human subjects

Journal of allergy and clinical immunology, 2014-07, Vol.134 (1), p.127-134.e9

2014

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Serum antioxidant vitamins and respiratory morbidity and mortality: a pooled analysis

Respiratory research, 2022-06, Vol.23 (1), p.150-150, Article 150

2022

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We need to talk about lung cancer’s cholesterol-hoarding problem

Cell stem cell, 2023-06, Vol.30 (6), p.745-747

Fessler, Michael B.

2023

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A New Frontier in Immunometabolism. Cholesterol in Lung Health and Disease

Annals of the American Thoracic Society, 2017-11, Vol.14 (Supplement_5), p.S399-S405

Fessler, Michael B

2017

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Palmitoylation of the immunity related GTPase, Irgm1: impact on membrane localization and ability to promote mitochondrial fission

PloS one, 2014-04, Vol.9 (4), p.e95021-e95021

2014

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CD11b/CD18 (Mac-1) is a novel surface receptor for extracellular double-stranded RNA to mediate cellular inflammatory responses

The Journal of immunology (1950), 2013-01, Vol.190 (1), p.115-125

2013

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Effects of Orally Ingested Arsenic on Respiratory Epithelial Permeability to Bacteria and Small Molecules in Mice

Environmental health perspectives, 2017-09, Vol.125 (9), p.097024-097024

2017

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Association of distance to swine concentrated animal feeding operations with immune-mediated diseases: An exploratory gene-environment study

Environment international, 2023-01, Vol.171, p.107687-107687, Article 107687

2023

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Relationship between serum cholesterol and indices of erythrocytes and platelets in the US population[S]

Journal of lipid research, 2013-11, Vol.54 (11), p.3177-3188

2013

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The challenges and promise of targeting the Liver X Receptors for treatment of inflammatory disease

Macrophage polarization in innate immune responses contributing to pathogenesis of chronic kidney disease

CD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation

Myeloid Deletion of SIRT1 Induces Inflammatory Signaling in Response to Environmental Stress

The Toll-like receptor gene family is integrated into human DNA damage and p53 networks

Macrophage ABCA1 reduces MyD88-dependent Toll-like receptor trafficking to lipid rafts by reduction of lipid raft cholesterol[S]

Cholesterol biosynthesis modulates differentiation in murine cranial neural crest cells

IRGM1 supports host defense against intracellular bacteria through suppression of type I interferon in mice

Race-specific association of an IRGM risk allele with cytokine expression in human subjects

Comparative and network-based proteomic analysis of low dose ethanol- and lipopolysaccharide-induced macrophages

Implementing machine learning methods with complex survey data: Lessons learned on the impacts of accounting sampling weights in gradient boosting

The Intracellular Cholesterol Landscape: Dynamic Integrator of the Immune Response

Toll-like receptor signaling links dietary fatty acids to the metabolic syndrome

Cross-linking Proteomics Indicates Effects of Simvastatin on the TLR2 Interactome and Reveals ACTR1A as a Novel Regulator of the TLR2 Signal Cascade[S]

Mechanisms of neutrophil accumulation in the lungs against bacteria

APOε4 is associated with enhanced in vivo innate immune responses in human subjects

Serum antioxidant vitamins and respiratory morbidity and mortality: a pooled analysis

We need to talk about lung cancer’s cholesterol-hoarding problem

TLR5 participates in the TLR4 receptor complex and promotes MyD88-dependent signaling in environmental lung injury

A New Frontier in Immunometabolism. Cholesterol in Lung Health and Disease

Palmitoylation of the immunity related GTPase, Irgm1: impact on membrane localization and ability to promote mitochondrial fission

CD11b/CD18 (Mac-1) is a novel surface receptor for extracellular double-stranded RNA to mediate cellular inflammatory responses

Effects of Orally Ingested Arsenic on Respiratory Epithelial Permeability to Bacteria and Small Molecules in Mice

Association of distance to swine concentrated animal feeding operations with immune-mediated diseases: An exploratory gene-environment study

Relationship between serum cholesterol and indices of erythrocytes and platelets in the US population[S]

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