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Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis

PLoS medicine, 2020-03, Vol.17 (3), p.e1003062-e1003062

2020

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Effect of Naturally Random Allocation to Lower Low-Density Lipoprotein Cholesterol on the Risk of Coronary Heart Disease Mediated by Polymorphisms in NPC1L1 , HMGCR , or Both

Journal of the American College of Cardiology, 2015-04, Vol.65 (15), p.1552-1561

2015

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Mendelian Randomization Study of ACLY and Cardiovascular Disease

The New England journal of medicine, 2019-03, Vol.380 (11), p.1033-1042

2019

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How to use Mendelian randomization to anticipate the results of randomized trials

European heart journal, 2018-02, Vol.39 (5), p.360-362

Ference, Brian A

2018

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Impact of Lipids on Cardiovascular Health: JACC Health Promotion Series

Journal of the American College of Cardiology, 2018-09, Vol.72 (10), p.1141-1156

2018

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The Potential Clinical Benefit of Lowering Lipoprotein(a)

JAMA : the journal of the American Medical Association, 2022-05, Vol.327 (17), p.1653

Ference, Brian A

2022

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Interpreting the Clinical Implications of Drug-Target Mendelian Randomization Studies

Journal of the American College of Cardiology, 2022-08, Vol.80 (7), p.663-665

Ference, Brian A.

2022

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World Heart Federation Cholesterol Roadmap 2022

Global heart, 2022-01, Vol.17 (1), p.75-75

2022

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The Role of Early LDL Lowering to Prevent the Onset of Atherosclerotic Disease

Current atherosclerosis reports, 2013-04, Vol.15 (4), p.312-312, Article 312

2013

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Mendelian randomization studies: using naturally randomized genetic data to fill evidence gaps

Current opinion in lipidology, 2015-12, Vol.26 (6), p.566-571

Ference, Brian A

2015

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Using Genetic Variants in the Targets of Lipid Lowering Therapies to Inform Drug Discovery and Development: Current and Future Treatment Options

Clinical pharmacology and therapeutics, 2019-03, Vol.105 (3), p.568-581

Ference, Brian A.

2019

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Effect of naturally random allocation to lower low-density lipoprotein cholesterol on the risk of coronary heart disease mediated by polymorphisms in NPC1L1, HMGCR, or both: a 2 × 2 factorial Mendelian randomization study

Journal of the American College of Cardiology, 2015-04, Vol.65 (15), p.1552-1561

2015

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Using Mendelian Randomization to Improve the Design of Randomized Trials

Cold Spring Harbor perspectives in biology, 2021-07, Vol.11 (7), p.a040980

2021

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A common KIF6 polymorphism increases vulnerability to low-density lipoprotein cholesterol: two meta-analyses and a meta-regression analysis

PloS one, 2011-12, Vol.6 (12), p.e28834-e28834

2011

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Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis

JAMA : the journal of the American Medical Association, 2016-09, Vol.316 (12), p.1289

2016

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Causal Effect of Lipids and Lipoproteins on Atherosclerosis: Lessons from Genomic Studies

Cardiology clinics, 2018-05, Vol.36 (2), p.203

Ference, Brian A

2018

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Variation in PCSK9 and HMGCR and Risk of Cardiovascular Disease and Diabetes

The New England journal of medicine, 2016-12, Vol.375 (22), p.2144-2153

2016

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Reduction of low density lipoprotein-cholesterol and cardiovascular events with proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors and statins: an analysis of FOURIER, SPIRE, and the Cholesterol Treatment Trialists Collaboration

European heart journal, 2018-07, Vol.39 (27), p.2540-2545

2018

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Effect of Long-Term Exposure to Lower Low-Density Lipoprotein Cholesterol Beginning Early in Life on the Risk of Coronary Heart Disease: A Mendelian Randomization Analysis

Journal of the American College of Cardiology, 2012-12, Vol.60 (25), p.2631-2639

2012

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Association of Triglyceride-Lowering LPL Variants and LDL-C-Lowering LDLR Variants With Risk of Coronary Heart Disease

JAMA : the journal of the American Medical Association, 2019-01, Vol.321 (4), p.364

2019

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Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement

European heart journal, 2022-10, Vol.43 (39), p.3925-3946

2022

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Association Between Triglyceride Lowering and Reduction of Cardiovascular Risk Across Multiple Lipid-Lowering Therapeutic Classes: A Systematic Review and Meta-Regression Analysis of Randomized Controlled Trials

Circulation (New York, N.Y.), 2019-10, Vol.140 (16), p.1308-1317

2019

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Lipids and Lipoproteins in 2020

JAMA : the journal of the American Medical Association, 2020-08, Vol.324 (6), p.595

2020

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Integrating genomics with biomarkers and therapeutic targets to invigorate cardiovascular drug development

Nature reviews cardiology, 2021-06, Vol.18 (6), p.435-453

2021

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Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis

Effect of Naturally Random Allocation to Lower Low-Density Lipoprotein Cholesterol on the Risk of Coronary Heart Disease Mediated by Polymorphisms in NPC1L1 , HMGCR , or Both

Mendelian Randomization Study of ACLY and Cardiovascular Disease

How to use Mendelian randomization to anticipate the results of randomized trials

Impact of Lipids on Cardiovascular Health: JACC Health Promotion Series

The Potential Clinical Benefit of Lowering Lipoprotein(a)

Interpreting the Clinical Implications of Drug-Target Mendelian Randomization Studies

World Heart Federation Cholesterol Roadmap 2022

The Role of Early LDL Lowering to Prevent the Onset of Atherosclerotic Disease

Mendelian randomization studies: using naturally randomized genetic data to fill evidence gaps

Using Genetic Variants in the Targets of Lipid Lowering Therapies to Inform Drug Discovery and Development: Current and Future Treatment Options

Effect of naturally random allocation to lower low-density lipoprotein cholesterol on the risk of coronary heart disease mediated by polymorphisms in NPC1L1, HMGCR, or both: a 2 × 2 factorial Mendelian randomization study

Using Mendelian Randomization to Improve the Design of Randomized Trials

A common KIF6 polymorphism increases vulnerability to low-density lipoprotein cholesterol: two meta-analyses and a meta-regression analysis

Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis

Causal Effect of Lipids and Lipoproteins on Atherosclerosis: Lessons from Genomic Studies

Variation in PCSK9 and HMGCR and Risk of Cardiovascular Disease and Diabetes

Reduction of low density lipoprotein-cholesterol and cardiovascular events with proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors and statins: an analysis of FOURIER, SPIRE, and the Cholesterol Treatment Trialists Collaboration

Effect of Long-Term Exposure to Lower Low-Density Lipoprotein Cholesterol Beginning Early in Life on the Risk of Coronary Heart Disease: A Mendelian Randomization Analysis

Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies—a consensus statement from the European Atherosclerosis Society

Association of Triglyceride-Lowering LPL Variants and LDL-C-Lowering LDLR Variants With Risk of Coronary Heart Disease

Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement

Association Between Triglyceride Lowering and Reduction of Cardiovascular Risk Across Multiple Lipid-Lowering Therapeutic Classes: A Systematic Review and Meta-Regression Analysis of Randomized Controlled Trials

Lipids and Lipoproteins in 2020

Integrating genomics with biomarkers and therapeutic targets to invigorate cardiovascular drug development

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