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Allosteric inhibition of protein tyrosine phosphatase 1B

Nature structural & molecular biology, 2004-08, Vol.11 (8), p.730-737

2004

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Fragment-Based Discovery of Nonpeptidic BACE-1 Inhibitors Using Tethering

Biochemistry (Easton), 2009-06, Vol.48 (21), p.4488-4496

2009

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Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors

Bioorganic & medicinal chemistry, 2008-10, Vol.18 (20), p.5648-5652

2008

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Tethering identifies fragment that yields potent inhibitors of human caspase-1

Bioorganic & medicinal chemistry letters, 2006-02, Vol.16 (3), p.559-562

2006

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Abstract LB006: PC14586: The first orally bioavailable small molecule reactivator of Y220C mutant p53 in clinical development

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.LB006-LB006

2021

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Total Synthesis of Aeruginosin 98B

Journal of the American Chemical Society, 2012-11, Vol.134 (46), p.18944-18947

2012

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Structural analysis of caspase-1 inhibitors derived from Tethering

Acta crystallographica. Section F, Structural biology and crystallization communications, 2005-05, Vol.61 (5), p.451-458

2005

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Novel Base-Induced [1,2]-Acyl Shift of Allylic Esters of Cyclopropanecarboxylic Acids

Journal of organic chemistry, 2000-04, Vol.65 (7), p.2239-2242

2000

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Identification of Potent and Selective Small-Molecule Inhibitors of Caspase-3 through the Use of Extended Tethering and Structure-Based Drug Design

Journal of medicinal chemistry, 2002-11, Vol.45 (23), p.5005-5022

2002

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Total Syntheses of the Cytotoxic Marine Natural Product, Aplysiapyranoid C1

Journal of organic chemistry, 1998-05, Vol.63 (9), p.2982-2987

1998

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Modifications of the isonipecotic acid fragment of SNS-032 : Analogs with improved permeability and lower efflux ratio

Bioorganic & medicinal chemistry, 2008-12, Vol.18 (23), p.6236-6239

2008

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A diaminocyclohexyl analog of SNS-032 with improved permeability and bioavailability properties

Bioorganic & medicinal chemistry, 2008-11, Vol.18 (21), p.5763-5765

2008

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Identification of potent and novel small-molecule inhibitors of caspase-3

Bioorganic & medicinal chemistry letters, 2003-11, Vol.13 (21), p.3651-3655

2003

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Total Syntheses of the Cytotoxic Marine Natural Product, Aplysiapyranoid C 1

Journal of organic chemistry, 1998-05, Vol.63 (9), p.2982-2987

1998

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Total syntheses of the cytotoxic marine natural product aplysiapyranoid C. Lewis acid catalyzed rearrangements of epoxy acetates, and novel base-catalyzed rearrangements of allylic esters

Fahr, Bruce Tabor

1998

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ProQuest

ChemInform Abstract: Novel Base-Induced [1,2]-Acyl Shift of Allylic Esters of Cyclopropanecarboxylic Acids

ChemInform, 2000-07, Vol.31 (30), p.no-no

2000

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Structural analysis of caspase-1 inhibitors derived from Tethering1

Acta crystallographica. Section F, Structural biology and crystallization communications, 2005-04, Vol.61 (Pt 5), p.451-458

2005

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Allosteric inhibition of protein tyrosine phosphatase 1B

Fragment-Based Discovery of Nonpeptidic BACE-1 Inhibitors Using Tethering

Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors

Tethering identifies fragment that yields potent inhibitors of human caspase-1

Abstract LB006: PC14586: The first orally bioavailable small molecule reactivator of Y220C mutant p53 in clinical development

Total Synthesis of Aeruginosin 98B

Structural analysis of caspase-1 inhibitors derived from Tethering

Novel Base-Induced [1,2]-Acyl Shift of Allylic Esters of Cyclopropanecarboxylic Acids

Methyl-substitution of an iminohydantoin spiropiperidine β-secretase (BACE-1) inhibitor has a profound effect on its potency

Identification of Potent and Selective Small-Molecule Inhibitors of Caspase-3 through the Use of Extended Tethering and Structure-Based Drug Design

Total Syntheses of the Cytotoxic Marine Natural Product, Aplysiapyranoid C1

Modifications of the isonipecotic acid fragment of SNS-032 : Analogs with improved permeability and lower efflux ratio

A diaminocyclohexyl analog of SNS-032 with improved permeability and bioavailability properties

Identification of potent and novel small-molecule inhibitors of caspase-3

Total Syntheses of the Cytotoxic Marine Natural Product, Aplysiapyranoid C 1

Total syntheses of the cytotoxic marine natural product aplysiapyranoid C. Lewis acid catalyzed rearrangements of epoxy acetates, and novel base-catalyzed rearrangements of allylic esters

ChemInform Abstract: Novel Base-Induced [1,2]-Acyl Shift of Allylic Esters of Cyclopropanecarboxylic Acids

Structural analysis of caspase-1 inhibitors derived from Tethering1

Accounting for detectability improves estimates of species richness in tropical bat surveys

Accounting for detectability improves estimates of species richness in tropical bat surveys: Species detectability in tropical bat surveys

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