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Signalling danger: endoplasmic reticulum stress and the unfolded protein response in pancreatic islet inflammation

Diabetologia, 2013-02, Vol.56 (2), p.234-241

2013

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A choice of death -the signal-transduction of immune-mediated beta-cell apoptosis

Diabetologia, 2001-12, Vol.44 (12), p.2115-2133

2001

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endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients

Diabetologia, 2007-12, Vol.50 (12), p.2486-2494

2007

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Expression of endoplasmic reticulum stress markers in the islets of patients with type 1 diabetes

Diabetologia, 2012-09, Vol.55 (9), p.2417-2420

2012

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Modulation of Autophagy Influences the Function and Survival of Human Pancreatic Beta Cells Under Endoplasmic Reticulum Stress Conditions and in Type 2 Diabetes

Frontiers in endocrinology (Lausanne), 2019-02, Vol.10, p.52-52

2019

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Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes

Diabetologia, 2010-07, Vol.53 (7), p.1395-1405

2010

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Sustained production of spliced X-box binding protein 1 (XBP1) induces pancreatic beta cell dysfunction and apoptosis

Diabetologia, 2010-06, Vol.53 (6), p.1120-1130

2010

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Conditional and Specific NF-κB Blockade Protects Pancreatic Beta Cells from Diabetogenic Agents

Proceedings of the National Academy of Sciences - PNAS, 2006-03, Vol.103 (13), p.5072-5077

2006

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Gene expression signatures of target tissues in type 1 diabetes, lupus erythematosus, multiple sclerosis, and rheumatoid arthritis

Science advances, 2021-01, Vol.7 (2)

2021

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Candidate genes for type 1 diabetes modulate pancreatic islet inflammation and β-cell apoptosis

Diabetes, obesity & metabolism, 2013-09, Vol.15 (s3), p.71-81

2013

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Global profiling of genes modified by endoplasmic reticulum stress in pancreatic beta cells reveals the early degradation of insulin mRNAs

Diabetologia, 2007-05, Vol.50 (5), p.1006-1014

2007

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Global profiling of coxsackievirus- and cytokine-induced gene expression in human pancreatic islets

Diabetologia, 2005-08, Vol.48 (8), p.1510-1522

2005

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Induction of nuclear factor-κB and its downstream genes by TNF-α and IL-1β has a pro-apoptotic role in pancreatic beta cells

Diabetologia, 2008-07, Vol.51 (7), p.1213-1225

2008

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Obstacles on the way to the clinical visualisation of beta cells: looking for the Aeneas of molecular imaging to navigate between Scylla and Charybdis

Diabetologia, 2012-05, Vol.55 (5), p.1247-1257

2012

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Interferon-γ potentiates endoplasmic reticulum stress-induced death by reducing pancreatic beta cell defence mechanisms

Diabetologia, 2006-06, Vol.49 (6), p.1229-1236

2006

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Deletion of C/EBP homologous protein (Chop) in C57Bl/6 mice dissociates obesity from insulin resistance

Diabetologia, 2012-04, Vol.55 (4), p.1167-1178

2012

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USP18 is a key regulator of the interferon-driven gene network modulating pancreatic beta cell inflammation and apoptosis

Cell death & disease, 2012-11, Vol.3 (11), p.e419-e419

2012

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Regulation by cytokines of the inducible nitric oxide synthase promoter in insulin-producing cells

Diabetologia, 1998-09, Vol.41 (9), p.1101-1108

1998

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Cytokines induce apoptosis in beta-cells isolated from mice lacking the inducible isoform of nitric oxide synthase (iNOS-/-)

Diabetes (New York, N.Y.), 2000-07, Vol.49 (7), p.1116-1122

2000

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Monocyte chemoattractant protein-1 is expressed in pancreatic islets from prediabetic NOD mice and in interleukin-1β-exposed human and rat islet cells

Diabetologia, 2001-03, Vol.44 (3), p.325-332

2001

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The harmony of the spheres : inducible nitric oxide synthase and related genes in pancreatic beta cells

Diabetologia, 1996-08, Vol.39 (8), p.875-890

1996

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beta-cell apoptosis and defense mechanisms: lessons from type 1 diabetes

Diabetes (New York, N.Y.), 2001-02, Vol.50 (suppl 1), p.S64-S69

2001

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Reduced sensitivity of inducible nitric oxide synthase-deficient mice to multiple low-dose streptozotocin-induced diabetes

Diabetes (New York, N.Y.), 1999-04, Vol.48 (4), p.706

1999

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IL-1β and IFN-γ induce the expression of diverse chemokines and IL-15 in human and rat pancreatic islet cells, and in islets from pre-diabetic NOD mice

Diabetologia, 2003-02, Vol.46 (2), p.255-266

2003

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Interferon regulatory factor-1 is a key transcription factor in murine beta cells under immune attack

Diabetologia, 2009-11, Vol.52 (11), p.2374-2384

2009

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Signalling danger: endoplasmic reticulum stress and the unfolded protein response in pancreatic islet inflammation

A choice of death -the signal-transduction of immune-mediated beta-cell apoptosis

endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients

Expression of endoplasmic reticulum stress markers in the islets of patients with type 1 diabetes

Modulation of Autophagy Influences the Function and Survival of Human Pancreatic Beta Cells Under Endoplasmic Reticulum Stress Conditions and in Type 2 Diabetes

Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes

Sustained production of spliced X-box binding protein 1 (XBP1) induces pancreatic beta cell dysfunction and apoptosis

Conditional and Specific NF-κB Blockade Protects Pancreatic Beta Cells from Diabetogenic Agents

Gene expression signatures of target tissues in type 1 diabetes, lupus erythematosus, multiple sclerosis, and rheumatoid arthritis

Candidate genes for type 1 diabetes modulate pancreatic islet inflammation and β-cell apoptosis

Global profiling of genes modified by endoplasmic reticulum stress in pancreatic beta cells reveals the early degradation of insulin mRNAs

Global profiling of coxsackievirus- and cytokine-induced gene expression in human pancreatic islets

Induction of nuclear factor-κB and its downstream genes by TNF-α and IL-1β has a pro-apoptotic role in pancreatic beta cells

Obstacles on the way to the clinical visualisation of beta cells: looking for the Aeneas of molecular imaging to navigate between Scylla and Charybdis

Interferon-γ potentiates endoplasmic reticulum stress-induced death by reducing pancreatic beta cell defence mechanisms

Deletion of C/EBP homologous protein (Chop) in C57Bl/6 mice dissociates obesity from insulin resistance

USP18 is a key regulator of the interferon-driven gene network modulating pancreatic beta cell inflammation and apoptosis

Regulation by cytokines of the inducible nitric oxide synthase promoter in insulin-producing cells

Cytokines induce apoptosis in beta-cells isolated from mice lacking the inducible isoform of nitric oxide synthase (iNOS-/-)

Monocyte chemoattractant protein-1 is expressed in pancreatic islets from prediabetic NOD mice and in interleukin-1β-exposed human and rat islet cells

The harmony of the spheres : inducible nitric oxide synthase and related genes in pancreatic beta cells

beta-cell apoptosis and defense mechanisms: lessons from type 1 diabetes

Reduced sensitivity of inducible nitric oxide synthase-deficient mice to multiple low-dose streptozotocin-induced diabetes

IL-1β and IFN-γ induce the expression of diverse chemokines and IL-15 in human and rat pancreatic islet cells, and in islets from pre-diabetic NOD mice

Interferon regulatory factor-1 is a key transcription factor in murine beta cells under immune attack

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