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CHK1 as a therapeutic target to bypass chemoresistance in AML

Science signaling, 2016-09, Vol.9 (445), p.ra90

2016

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LOSS OF HSC STEMNESS IDENTITY IS ASSOCIATED WITH EXHAUSTION AND HYPORESPONSIVENESS IN GATA2 DEFICIENCY SYNDROME

EJC paediatric oncology, 2023-12, Vol.2, p.100052, Article 100052

2023

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Inhibition of proteasome activity impairs centrosome-dependent microtubule nucleation and organization

Molecular biology of the cell, 2008-03, Vol.19 (3), p.1220-1229

2008

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Evaluation of checkpoint kinase targeting therapy in Acute Myeloid Leukemia with complex karyotype

Cancer biology & therapy, 2012-03, Vol.13 (5), p.307-313

2012

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Regulation of CHK1 by the Ubiquitin–Proteasome System

The FEBS journal, 2020-05, Vol.287 (10), p.1982-1984

2020

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RNF5, a RING Finger Protein That Regulates Cell Motility by Targeting Paxillin Ubiquitination and Altered Localization

Molecular and Cellular Biology, 2003-08, Vol.23 (15), p.5331-5345

2003

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The small ubiquitin-like modifier (SUMO) is required for gonadal and uterine-vulval morphogenesis in Caenorhabditis elegans

Genes & development, 2004-10, Vol.18 (19), p.2380-2391

2004

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Targeting ATR/CHK1 pathway in acute myeloid leukemia to overcome chemoresistance

Molecular & cellular oncology, 2017-09, Vol.4 (5), p.e1289293-e1289293

2017

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The LIM Domain Protein UNC-95 Is Required for the Assembly of Muscle Attachment Structures and Is Regulated by the RING Finger Protein RNF-5 in C. elegans

The Journal of cell biology, 2004-06, Vol.165 (6), p.857-867

2004

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JAMP, a Jun N-Terminal Kinase 1 (JNK1)-Associated Membrane Protein, Regulates Duration of JNK Activity

Molecular and Cellular Biology, 2005-10, Vol.25 (19), p.8619-8630

2005

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New Approach to Decipher GATA2 Deficiency Syndrome: Focus on the Recurrent GATA2 R396Q Mutation

Blood, 2021-12, Vol.138 (Supplement 1), p.27-27

2021

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Inhibition of ubiquitin-specific protease 7 sensitizes acute myeloid leukemia to chemotherapy

Leukemia, 2021-02, Vol.35 (2), p.417-432

2021

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A PIM-CHK1 signaling pathway regulates PLK1 phosphorylation and function during mitosis

Journal of cell science, 2018-08, Vol.131 (15)

2018

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CELL QUIESCENCE AND REPROGRAMMING ARE DISTINCTIVE FEATURES OF PRE- LEUKEMIC STEM CELLS IN BACUTE LYMPHOBLASTIC LEUKEMIA

Experimental hematology, 2022, Vol.111, p.S86-S86

2022

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3084 – CELL QUIESCENCE AND REPROGRAMMING ARE DISTINCTIVE FEATURES OF PRE-LEUKEMIC STEM CELLS IN B-ACUTE LYMPHOBLASTIC LEUKEMIA

Experimental hematology, 2022, Vol.111, p.S86-S87

2022

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Targeting CHK1 inhibits cell proliferation in FLT3-ITD positive acute myeloid leukemia

Leukemia research, 2014-11, Vol.38 (11), p.1342-1349

2014

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Constitutive Activation of the DNA Damage Signaling Pathway in Acute Myeloid Leukemia with Complex Karyotype: Potential Importance for Checkpoint Targeting Therapy

Cancer research (Chicago, Ill.), 2009-11, Vol.69 (22), p.8652-8661

2009

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Modulation of exogenous and endogenous levels of thioredoxin in human skin fibroblasts prevents DNA damaging effect of ultraviolet A radiation

Free radical biology & medicine, 2001-03, Vol.30 (5), p.537-546

2001

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CDC25A governs proliferation and differentiation of FLT3-ITD acute myeloid leukemia

Oncotarget, 2015-11, Vol.6 (35), p.38061-38078

2015

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G2 M checkpoint stringency is a key parameter in the sensitivity of AML cells to genotoxic stress

Oncogene, 2008-06, Vol.27 (27), p.3811-3820

2008

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Evaluation of Polo-like Kinase 1 inhibition on the G2/M checkpoint in Acute Myelocytic Leukaemia

European journal of pharmacology, 2008-09, Vol.591 (1), p.102-105

2008

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Evaluation of checkpoint kinase targeting therapy in acute myeloid leukemia with complex karyotype

Cancer biology & therapy, 2012-03, Vol.13 (5), p.307-313

2012

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ENABLING CROP DIVERSIFICATION TO SUPPORT TRANSITIONS TOWARD MORE SUSTAINABLE EUROPEAN AGRIFOOD SYSTEMS

Frontiers of agricultural science and engineering, 2021, Vol.8 (3), p.474-480

2021

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Cell adhesion regulates CDC25A expression and proliferation in acute myeloid leukemia

Cancer research (Chicago, Ill.), 2006-07, Vol.66 (14), p.7128-7135

2006

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Induction of thioredoxin by ultraviolet-A radiation prevents oxidative-mediated cell death in human skin fibroblasts

Free radical biology & medicine, 2001-09, Vol.31 (5), p.585-598

2001

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CHK1 as a therapeutic target to bypass chemoresistance in AML

LOSS OF HSC STEMNESS IDENTITY IS ASSOCIATED WITH EXHAUSTION AND HYPORESPONSIVENESS IN GATA2 DEFICIENCY SYNDROME

Inhibition of proteasome activity impairs centrosome-dependent microtubule nucleation and organization

Evaluation of checkpoint kinase targeting therapy in Acute Myeloid Leukemia with complex karyotype

Regulation of CHK1 by the Ubiquitin–Proteasome System

RNF5, a RING Finger Protein That Regulates Cell Motility by Targeting Paxillin Ubiquitination and Altered Localization

The small ubiquitin-like modifier (SUMO) is required for gonadal and uterine-vulval morphogenesis in Caenorhabditis elegans

Targeting ATR/CHK1 pathway in acute myeloid leukemia to overcome chemoresistance

The LIM Domain Protein UNC-95 Is Required for the Assembly of Muscle Attachment Structures and Is Regulated by the RING Finger Protein RNF-5 in C. elegans

JAMP, a Jun N-Terminal Kinase 1 (JNK1)-Associated Membrane Protein, Regulates Duration of JNK Activity

New Approach to Decipher GATA2 Deficiency Syndrome: Focus on the Recurrent GATA2 R396Q Mutation

Inhibition of ubiquitin-specific protease 7 sensitizes acute myeloid leukemia to chemotherapy

A PIM-CHK1 signaling pathway regulates PLK1 phosphorylation and function during mitosis

CELL QUIESCENCE AND REPROGRAMMING ARE DISTINCTIVE FEATURES OF PRE- LEUKEMIC STEM CELLS IN BACUTE LYMPHOBLASTIC LEUKEMIA

3084 – CELL QUIESCENCE AND REPROGRAMMING ARE DISTINCTIVE FEATURES OF PRE-LEUKEMIC STEM CELLS IN B-ACUTE LYMPHOBLASTIC LEUKEMIA

Targeting CHK1 inhibits cell proliferation in FLT3-ITD positive acute myeloid leukemia

Constitutive Activation of the DNA Damage Signaling Pathway in Acute Myeloid Leukemia with Complex Karyotype: Potential Importance for Checkpoint Targeting Therapy

Modulation of exogenous and endogenous levels of thioredoxin in human skin fibroblasts prevents DNA damaging effect of ultraviolet A radiation

CDC25A governs proliferation and differentiation of FLT3-ITD acute myeloid leukemia

G2 M checkpoint stringency is a key parameter in the sensitivity of AML cells to genotoxic stress

Evaluation of Polo-like Kinase 1 inhibition on the G2/M checkpoint in Acute Myelocytic Leukaemia

Evaluation of checkpoint kinase targeting therapy in acute myeloid leukemia with complex karyotype

ENABLING CROP DIVERSIFICATION TO SUPPORT TRANSITIONS TOWARD MORE SUSTAINABLE EUROPEAN AGRIFOOD SYSTEMS

Cell adhesion regulates CDC25A expression and proliferation in acute myeloid leukemia

Induction of thioredoxin by ultraviolet-A radiation prevents oxidative-mediated cell death in human skin fibroblasts

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