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Reconstructing kinase network topologies from phosphoproteomics data reveals cancer-associated rewiring

Nature biotechnology, 2020-04, Vol.38 (4), p.493-502

2020

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Drug ranking using machine learning systematically predicts the efficacy of anti-cancer drugs

Nature communications, 2021-03, Vol.12 (1), p.1850-15, Article 1850

2021

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Community detection in empirical kinase networks identifies new potential members of signalling pathways

PLoS computational biology, 2023-06, Vol.19 (6), p.e1010459-e1010459

2023

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Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics

Journal of proteome research, 2017-08, Vol.16 (8), p.3083-3091

2017

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Deconstruction of a Metastatic Tumor Microenvironment Reveals a Common Matrix Response in Human Cancers

Cancer discovery, 2018-03, Vol.8 (3), p.304-319

2018

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A Strong B-cell Response Is Part of the Immune Landscape in Human High-Grade Serous Ovarian Metastases

Clinical cancer research, 2017-01, Vol.23 (1), p.250-262

2017

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Shedding of bevacizumab in tumour cells-derived extracellular vesicles as a new therapeutic escape mechanism in glioblastoma

Molecular cancer, 2018-08, Vol.17 (1), p.132-132, Article 132

2018

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Role of phosphoproteomics in the development of personalized cancer therapies

Proteomics. Clinical applications, 2015-04, Vol.9 (3-4), p.383-395

Cutillas, Pedro R.

2015

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Large-scale models of signal propagation in human cells derived from discovery phosphoproteomic data

Nature communications, 2015-09, Vol.6 (1), p.8033-8033, Article 8033

2015

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Impact of phosphoproteomics in the translation of kinase‐targeted therapies

Proteomics (Weinheim), 2017-03, Vol.17 (6), p.np-n/a

2017

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Sequence and Structure-Based Analysis of Specificity Determinants in Eukaryotic Protein Kinases

Cell reports (Cambridge), 2021-01, Vol.34 (2), p.108602-108602, Article 108602

2021

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Elucidating the role of the kinase activity of endothelial cell focal adhesion kinase in angiocrine signalling and tumour growth

The Journal of pathology, 2022-02, Vol.256 (2), p.235-247

2022

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Computational Analysis of Cholangiocarcinoma Phosphoproteomes Identifies Patient-Specific Drug Targets

Cancer research (Chicago, Ill.), 2021-11, Vol.81 (22), p.5765-5776

2021

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HDAC Inhibition Restores Response to HER2-Targeted Therapy in Breast Cancer via PHLDA1 Induction

International journal of molecular sciences, 2023-03, Vol.24 (7), p.6228

2023

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Characterization of a TiO2 enrichment method for label-free quantitative phosphoproteomics

Methods (San Diego, Calif.), 2011-08, Vol.54 (4), p.370-378

2011

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A class I PI3K signalling network regulates primary cilia disassembly in normal physiology and disease

Nature communications, 2024-08, Vol.15 (1), p.7181-21

2024

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Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility

Nature communications, 2018-11, Vol.9 (1), p.4826-16, Article 4826

2018

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Quantitative Profile of Five Murine Core Proteomes Using Label-free Functional Proteomics

Molecular & cellular proteomics, 2007-09, Vol.6 (9), p.1560-1573

2007

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PARP-1 activation after oxidative insult promotes energy stress-dependent phosphorylation of YAP1 and reduces cell viability

Biochemical journal, 2020-12, Vol.477 (23), p.4491-4513

2020

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Class IA phosphoinositide 3-kinases are obligate p85-p110 heterodimers

Proceedings of the National Academy of Sciences - PNAS, 2007-05, Vol.104 (19), p.7809-7814

2007

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Perineural invasion in pancreatic cancer: proteomic analysis and in vitro modelling

Molecular oncology, 2019-05, Vol.13 (5), p.1075-1091

2019

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Proteomic Characterization of Acute Myeloid Leukemia for Precision Medicine

Molecular & cellular proteomics, 2023-04, Vol.22 (4), p.100517-100517, Article 100517

2023

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In Silico Analysis Predicts Nuclear Factors NR2F6 and YAP1 as Mesenchymal Subtype-Specific Therapeutic Targets for Ovarian Cancer Patients

Cancers, 2023-06, Vol.15 (12), p.3155

2023

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Principles of phosphoproteomics and applications in cancer research

Biochemical journal, 2023-03, Vol.480 (6), p.403-420

2023

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Polyamine production is downstream and upstream of oncogenic PI3K signalling and contributes to tumour cell growth

Biochemical journal, 2013-03, Vol.450 (3), p.619-628

2013

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Reconstructing kinase network topologies from phosphoproteomics data reveals cancer-associated rewiring

Drug ranking using machine learning systematically predicts the efficacy of anti-cancer drugs

Community detection in empirical kinase networks identifies new potential members of signalling pathways

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics

Deconstruction of a Metastatic Tumor Microenvironment Reveals a Common Matrix Response in Human Cancers

A Strong B-cell Response Is Part of the Immune Landscape in Human High-Grade Serous Ovarian Metastases

Shedding of bevacizumab in tumour cells-derived extracellular vesicles as a new therapeutic escape mechanism in glioblastoma

Role of phosphoproteomics in the development of personalized cancer therapies

Large-scale models of signal propagation in human cells derived from discovery phosphoproteomic data

Impact of phosphoproteomics in the translation of kinase‐targeted therapies

Sequence and Structure-Based Analysis of Specificity Determinants in Eukaryotic Protein Kinases

Elucidating the role of the kinase activity of endothelial cell focal adhesion kinase in angiocrine signalling and tumour growth

Computational Analysis of Cholangiocarcinoma Phosphoproteomes Identifies Patient-Specific Drug Targets

HDAC Inhibition Restores Response to HER2-Targeted Therapy in Breast Cancer via PHLDA1 Induction

Characterization of a TiO2 enrichment method for label-free quantitative phosphoproteomics

A class I PI3K signalling network regulates primary cilia disassembly in normal physiology and disease

Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility

Quantitative Profile of Five Murine Core Proteomes Using Label-free Functional Proteomics

PARP-1 activation after oxidative insult promotes energy stress-dependent phosphorylation of YAP1 and reduces cell viability

Class IA phosphoinositide 3-kinases are obligate p85-p110 heterodimers

Perineural invasion in pancreatic cancer: proteomic analysis and in vitro modelling

Proteomic Characterization of Acute Myeloid Leukemia for Precision Medicine

In Silico Analysis Predicts Nuclear Factors NR2F6 and YAP1 as Mesenchymal Subtype-Specific Therapeutic Targets for Ovarian Cancer Patients

Principles of phosphoproteomics and applications in cancer research

Polyamine production is downstream and upstream of oncogenic PI3K signalling and contributes to tumour cell growth

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