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Rapid and non-invasive detection of malaria parasites using near-infrared spectroscopy and machine learning

PloS one, 2024-03, Vol.19 (3), p.e0289232-e0289232

2024

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Cross-sectional survey of asymptomatic malaria in Dak Nong province in the Central Highlands of Vietnam for the malaria elimination roadmap

PloS one, 2021-10, Vol.16 (10)

2021

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Role of pfmdr1 Amplification and Expression in Induction of Resistance to Artemisinin Derivatives in Plasmodium falciparum

Antimicrobial Agents and Chemotherapy, 2010-06, Vol.54 (6), p.2455-2464

2010

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Cross-sectional survey of asymptomatic malaria in Dak Nong province in the Central Highlands of Vietnam for the malaria elimination roadmap

PloS one, 2021-10, Vol.16 (10), p.e0258580-e0258580

2021

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Cross-sectional study of asymptomatic malaria and seroepidemiological surveillance of seven districts in Gia Lai province, Vietnam

Malaria journal, 2022-02, Vol.21 (1), p.40-40, Article 40

2022

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Chloroquine resistant Plasmodium vivax: in vitro characterisation and association with molecular polymorphisms

PloS one, 2007-10, Vol.2 (10), p.e1089

2007

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Susceptibility of Plasmodium falciparum to artemisinins and Plasmodium vivax to chloroquine in Phuoc Chien Commune, Ninh Thuan Province, south-central Vietnam

Malaria journal, 2019-01, Vol.18 (1), p.10-10, Article 10

2019

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Correlation between Cyclin Dependent Kinases and Artemisinin-Induced Dormancy in Plasmodium falciparum In Vitro

PloS one, 2016-06, Vol.11 (6), p.e0157906

2016

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Targeting protein kinases in the malaria parasite: update of an antimalarial drug target

Current topics in medicinal chemistry, 2012-03, Vol.12 (5), p.456

2012

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Development of cultured Plasmodium falciparum blood-stage malaria cell banks for early phase in vivo clinical trial assessment of anti-malaria drugs and vaccines

Malaria journal, 2015-04, Vol.14 (1), p.143-143, Article 143

2015

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Deamplification of pfmdr1-Containing Amplicon on Chromosome 5 in Plasmodium falciparum Is Associated with Reduced Resistance to Artelinic Acid In Vitro

Antimicrobial Agents and Chemotherapy, 2010-08, Vol.54 (8), p.3395-3401

2010

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Pharmacokinetics and Ex Vivo Pharmacodynamic Antimalarial Activity of Dihydroartemisinin-Piperaquine in Patients with Uncomplicated Falciparum Malaria in Vietnam

Antimicrobial Agents and Chemotherapy, 2009-08, Vol.53 (8), p.3534-3537

2009

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Pharmacokinetics and Ex Vivo Antimalarial Activity of Artesunate-Azithromycin in Healthy Volunteers

Antimicrobial Agents and Chemotherapy, 2011-09, Vol.55 (9), p.4412-4415

2011

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Mitochondrial Membrane Potential in a Small Subset of Artemisinin-Induced Dormant Plasmodium falciparum Parasites In Vitro

The Journal of infectious diseases, 2015-08, Vol.212 (3), p.426-434

2015

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Nucleotide analogues containing a pyrrolidine, piperidine or piperazine ring: Synthesis and evaluation of inhibition of plasmodial and human 6-oxopurine phosphoribosyltransferases and in vitro antimalarial activity

European journal of medicinal chemistry, 2021-07, Vol.219, p.113416-113416, Article 113416

2021

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Multidrug-Resistant Plasmodium falciparum Parasites in the Central Highlands of Vietnam Jeopardize Malaria Control and Elimination Strategies

Antimicrobial agents and chemotherapy, 2021-03, Vol.65 (4)

2021

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Pyronaridine-Artesunate (Pyramax) for Treatment of Artemisinin- and Piperaquine-Resistant Plasmodium falciparum in the Central Highlands of Vietnam

Antimicrobial agents and chemotherapy, 2021-11, Vol.65 (12), p.e0027621-e0027621

2021

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Aza-acyclic Nucleoside Phosphonates Containing a Second Phosphonate Group As Inhibitors of the Human, Plasmodium falciparum and vivax 6‑Oxopurine Phosphoribosyltransferases and Their Prodrugs As Antimalarial Agents

Journal of medicinal chemistry, 2015-01, Vol.58 (2), p.827-846

2015

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Synthesis and Evaluation of Asymmetric Acyclic Nucleoside Bisphosphonates as Inhibitors of Plasmodium falciparum and Human Hypoxanthine–Guanine–(Xanthine) Phosphoribosyltransferase

Journal of medicinal chemistry, 2017-09, Vol.60 (17), p.7539-7554

2017

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Antimalarial activity of prodrugs of N-branched acyclic nucleoside phosphonate inhibitors of 6-oxopurine phosphoribosyltransferases

Bioorganic & medicinal chemistry, 2015-09, Vol.23 (17), p.5502-5510

2015

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Development of pyridyl thiosemicarbazones as highly potent agents for the treatment of malaria after oral administration

Journal of antimicrobial chemotherapy, 2019-10, Vol.74 (10), p.2965-2973

2019

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Pharmacokinetics and Ex Vivo Antimalarial Activity of Artesunate-Amodiaquine plus Methylene Blue in Healthy Volunteers

Antimicrobial agents and chemotherapy, 2020-02, Vol.64 (3)

2020

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Discovery of Potent and Fast-Acting Antimalarial Bis-1,2,4-triazines

Journal of medicinal chemistry, 2021-04, Vol.64 (7), p.4150-4162

2021

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Synthesis and evaluation of symmetric acyclic nucleoside bisphosphonates as inhibitors of the Plasmodium falciparum, Plasmodium vivax and human 6-oxopurine phosphoribosyltransferases and the antimalarial activity of their prodrugs

Bioorganic & medicinal chemistry, 2017-08, Vol.25 (15), p.4008-4030

2017

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The Spiroindolone KAE609 Does Not Induce Dormant Ring Stages in Plasmodium falciparum Parasites

Antimicrobial agents and chemotherapy, 2016-09, Vol.60 (9), p.5167-5174

2016

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Rapid and non-invasive detection of malaria parasites using near-infrared spectroscopy and machine learning

Cross-sectional survey of asymptomatic malaria in Dak Nong province in the Central Highlands of Vietnam for the malaria elimination roadmap

Role of pfmdr1 Amplification and Expression in Induction of Resistance to Artemisinin Derivatives in Plasmodium falciparum

Cross-sectional survey of asymptomatic malaria in Dak Nong province in the Central Highlands of Vietnam for the malaria elimination roadmap

Cross-sectional study of asymptomatic malaria and seroepidemiological surveillance of seven districts in Gia Lai province, Vietnam

Chloroquine resistant Plasmodium vivax: in vitro characterisation and association with molecular polymorphisms

Susceptibility of Plasmodium falciparum to artemisinins and Plasmodium vivax to chloroquine in Phuoc Chien Commune, Ninh Thuan Province, south-central Vietnam

Correlation between Cyclin Dependent Kinases and Artemisinin-Induced Dormancy in Plasmodium falciparum In Vitro

Targeting protein kinases in the malaria parasite: update of an antimalarial drug target

Development of cultured Plasmodium falciparum blood-stage malaria cell banks for early phase in vivo clinical trial assessment of anti-malaria drugs and vaccines

Deamplification of pfmdr1-Containing Amplicon on Chromosome 5 in Plasmodium falciparum Is Associated with Reduced Resistance to Artelinic Acid In Vitro

Pharmacokinetics and Ex Vivo Pharmacodynamic Antimalarial Activity of Dihydroartemisinin-Piperaquine in Patients with Uncomplicated Falciparum Malaria in Vietnam

Pharmacokinetics and Ex Vivo Antimalarial Activity of Artesunate-Azithromycin in Healthy Volunteers

Mitochondrial Membrane Potential in a Small Subset of Artemisinin-Induced Dormant Plasmodium falciparum Parasites In Vitro

Nucleotide analogues containing a pyrrolidine, piperidine or piperazine ring: Synthesis and evaluation of inhibition of plasmodial and human 6-oxopurine phosphoribosyltransferases and in vitro antimalarial activity

Multidrug-Resistant Plasmodium falciparum Parasites in the Central Highlands of Vietnam Jeopardize Malaria Control and Elimination Strategies

Pyronaridine-Artesunate (Pyramax) for Treatment of Artemisinin- and Piperaquine-Resistant Plasmodium falciparum in the Central Highlands of Vietnam

Aza-acyclic Nucleoside Phosphonates Containing a Second Phosphonate Group As Inhibitors of the Human, Plasmodium falciparum and vivax 6‑Oxopurine Phosphoribosyltransferases and Their Prodrugs As Antimalarial Agents

Synthesis and Evaluation of Asymmetric Acyclic Nucleoside Bisphosphonates as Inhibitors of Plasmodium falciparum and Human Hypoxanthine–Guanine–(Xanthine) Phosphoribosyltransferase

Antimalarial activity of prodrugs of N-branched acyclic nucleoside phosphonate inhibitors of 6-oxopurine phosphoribosyltransferases

Development of pyridyl thiosemicarbazones as highly potent agents for the treatment of malaria after oral administration

Pharmacokinetics and Ex Vivo Antimalarial Activity of Artesunate-Amodiaquine plus Methylene Blue in Healthy Volunteers

Discovery of Potent and Fast-Acting Antimalarial Bis-1,2,4-triazines

Synthesis and evaluation of symmetric acyclic nucleoside bisphosphonates as inhibitors of the Plasmodium falciparum, Plasmodium vivax and human 6-oxopurine phosphoribosyltransferases and the antimalarial activity of their prodrugs

The Spiroindolone KAE609 Does Not Induce Dormant Ring Stages in Plasmodium falciparum Parasites

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