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Pro-oxidant natural products as anticancer agents

Current drug targets, 2012-07, Vol.13 (8), p.1006

2012

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The Coffee Constituent Chlorogenic Acid Induces Cellular DNA Damage and Formation of Topoisomerase I– and II–DNA Complexes in Cells

Journal of agricultural and food chemistry, 2012-08, Vol.60 (30), p.7384-7391

2012

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Evaluating the Cancer Therapeutic Potential of Cardiac Glycosides

BioMed research international, 2014-01, Vol.2014, p.794930-9

2014

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Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities

Cell reports (Cambridge), 2016-01, Vol.14 (2), p.298-309

2016

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Sulforaphane homologues: Enantiodivergent synthesis of both enantiomers, activation of the Nrf2 transcription factor and selective cytotoxic activity

European journal of medicinal chemistry, 2014-11, Vol.87, p.552-563

2014

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The dark side of curcumin

International journal of cancer, 2010-04, Vol.126 (7), p.1771-1775

2010

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Selective cytotoxic activity and DNA damage by an epoxyalkyl galactopyranoside

Drug development research, 2018-12, Vol.79 (8), p.426-436

2018

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Carbohydrate-Based NK1R Antagonists with Broad-Spectrum Anticancer Activity

Journal of medicinal chemistry, 2021-07, Vol.64 (14), p.10350-10370

2021

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Cells Deficient in the Fanconi Anemia Protein FANCD2 are Hypersensitive to the Cytotoxicity and DNA Damage Induced by Coffee and Caffeic Acid

Toxins, 2016-07, Vol.8 (7), p.211-211

2016

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Manipulation of Amino Acid Levels with Artificial Diets Induces a Marked Anticancer Activity in Mice with Renal Cell Carcinoma

International journal of molecular sciences, 2022-12, Vol.23 (24), p.16132

2022

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Repurposing Study of 4-Acyl-1-phenylaminocarbonyl-2-substituted-piperazine Derivatives as Potential Anticancer Agents-In Vitro Evaluation against Breast Cancer Cells

International journal of molecular sciences, 2023-12, Vol.24 (23), p.17041

2023

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Artificial Diets with Altered Levels of Sulfur Amino Acids Induce Anticancer Activity in Mice with Metastatic Colon Cancer, Ovarian Cancer and Renal Cell Carcinoma

International journal of molecular sciences, 2023-02, Vol.24 (5), p.4587

2023

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Artificial Diets Based on Selective Amino Acid Restriction versus Capecitabine in Mice with Metastatic Colon Cancer

Nutrients, 2022-08, Vol.14 (16), p.3378

2022

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Artificial Diets with Selective Restriction of Amino Acids and Very Low Levels of Lipids Induce Anticancer Activity in Mice with Metastatic Triple-Negative Breast Cancer

Cancers, 2023-02, Vol.15 (5), p.1540

2023

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Overexpressed c-Myc Sensitizes Cells to TH1579, a Mitotic Arrest and Oxidative DNA Damage Inducer

Biomolecules (Basel, Switzerland), 2022-11, Vol.12 (12), p.1777

2022

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Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities

Cell reports (Cambridge), 2016-12, Vol.17 (12), p.3407-3416

2016

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Screening for Selective Anticancer Activity of 65 Extracts of Plants Collected in Western Andalusia, Spain

Plants (Basel), 2021-10, Vol.10 (10), p.2193

2021

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Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1

Journal of medicinal chemistry, 2017-03, Vol.60 (5), p.2148-2154

2017

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Cholesterol Levels Affect the Performance of AuNPs-Decorated Thermo-Sensitive Liposomes as Nanocarriers for Controlled Doxorubicin Delivery

Pharmaceutics, 2021-06, Vol.13 (7), p.973

2021

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Evaluation of Anticancer Activity of 76 Plant Species Collected in Andalusia (Spain) against Lung Cancer Cells

Plants (Basel), 2023-09, Vol.12 (18), p.3275

2023

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Green tea constituents (−)-epigallocatechin-3-gallate (EGCG) and gallic acid induce topoisomerase I- and topoisomerase II-DNA complexes in cells mediated by pyrogallol-induced hydrogen peroxide

Mutagenesis, 2011-07, Vol.26 (4), p.489-498

2011

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Selective Cytotoxic Activity of New Lipophilic Hydroxytyrosol Alkyl Ether Derivatives

Journal of agricultural and food chemistry, 2013-05, Vol.61 (21), p.5046-5053

2013

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Alpha, beta-unsaturated lactones 2-furanone and 2-pyrone induce cellular DNA damage, formation of topoisomerase I- and II-DNA complexes and cancer cell death

Toxicology letters, 2013-09, Vol.222 (1), p.64-71

2013

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In Vitro Anticancer Activity and Mechanism of Action of an Aziridinyl Galactopyranoside

Biomedicines, 2022-01, Vol.10 (1), p.41

2022

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Chirality influence on the cytotoxic properties of anionic chiral bis(N-heterocyclic carbene)silver complexes

Journal of inorganic biochemistry, 2022-10, Vol.235, p.111924-111924, Article 111924

2022

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Pro-oxidant natural products as anticancer agents

The Coffee Constituent Chlorogenic Acid Induces Cellular DNA Damage and Formation of Topoisomerase I– and II–DNA Complexes in Cells

Evaluating the Cancer Therapeutic Potential of Cardiac Glycosides

Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities

Sulforaphane homologues: Enantiodivergent synthesis of both enantiomers, activation of the Nrf2 transcription factor and selective cytotoxic activity

The dark side of curcumin

Selective cytotoxic activity and DNA damage by an epoxyalkyl galactopyranoside

Carbohydrate-Based NK1R Antagonists with Broad-Spectrum Anticancer Activity

Cells Deficient in the Fanconi Anemia Protein FANCD2 are Hypersensitive to the Cytotoxicity and DNA Damage Induced by Coffee and Caffeic Acid

Manipulation of Amino Acid Levels with Artificial Diets Induces a Marked Anticancer Activity in Mice with Renal Cell Carcinoma

Repurposing Study of 4-Acyl-1-phenylaminocarbonyl-2-substituted-piperazine Derivatives as Potential Anticancer Agents-In Vitro Evaluation against Breast Cancer Cells

Artificial Diets with Altered Levels of Sulfur Amino Acids Induce Anticancer Activity in Mice with Metastatic Colon Cancer, Ovarian Cancer and Renal Cell Carcinoma

Artificial Diets Based on Selective Amino Acid Restriction versus Capecitabine in Mice with Metastatic Colon Cancer

Artificial Diets with Selective Restriction of Amino Acids and Very Low Levels of Lipids Induce Anticancer Activity in Mice with Metastatic Triple-Negative Breast Cancer

Overexpressed c-Myc Sensitizes Cells to TH1579, a Mitotic Arrest and Oxidative DNA Damage Inducer

Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities

Screening for Selective Anticancer Activity of 65 Extracts of Plants Collected in Western Andalusia, Spain

Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1

Cholesterol Levels Affect the Performance of AuNPs-Decorated Thermo-Sensitive Liposomes as Nanocarriers for Controlled Doxorubicin Delivery

Evaluation of Anticancer Activity of 76 Plant Species Collected in Andalusia (Spain) against Lung Cancer Cells

Green tea constituents (−)-epigallocatechin-3-gallate (EGCG) and gallic acid induce topoisomerase I- and topoisomerase II-DNA complexes in cells mediated by pyrogallol-induced hydrogen peroxide

Selective Cytotoxic Activity of New Lipophilic Hydroxytyrosol Alkyl Ether Derivatives

Alpha, beta-unsaturated lactones 2-furanone and 2-pyrone induce cellular DNA damage, formation of topoisomerase I- and II-DNA complexes and cancer cell death

In Vitro Anticancer Activity and Mechanism of Action of an Aziridinyl Galactopyranoside

Chirality influence on the cytotoxic properties of anionic chiral bis(N-heterocyclic carbene)silver complexes

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