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Autophagy in neurodegenerative diseases: pathogenesis and therapy

Brain pathology (Zurich, Switzerland), 2018-01, Vol.28 (1), p.3-13

2018

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Therapeutic Effect of Berberine on Huntington's Disease Transgenic Mouse Model

PloS one, 2015-07, Vol.10 (7), p.e0134142-e0134142

2015

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MicroRNA-206: a potential circulating biomarker candidate for amyotrophic lateral sclerosis

PloS one, 2014-02, Vol.9 (2), p.e89065-e89065

2014

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The essential role of transcription factor Pitx3 in preventing mesodiencephalic dopaminergic neurodegeneration and maintaining neuronal subtype identities during aging

Cell death & disease, 2021-10, Vol.12 (11), p.1008-1008, Article 1008

2021

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Acute Hypoxia Induced an Imbalanced M1/M2 Activation of Microglia through NF-κB Signaling in Alzheimer's Disease Mice and Wild-Type Littermates

Frontiers in aging neuroscience, 2017-08, Vol.9, p.282-282

2017

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The Crucial Roles of Pitx3 in Midbrain Dopaminergic Neuron Development and Parkinson's Disease-Associated Neurodegeneration

International journal of molecular sciences, 2023-05, Vol.24 (10), p.8614

2023

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Impaired inflammatory responses in murine Lrrk2-knockdown brain microglia

PloS one, 2012-04, Vol.7 (4), p.e34693-e34693

2012

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Connectivity and Functionality of the Globus Pallidus Externa Under Normal Conditions and Parkinson's Disease

Frontiers in neural circuits, 2021-03, Vol.15, p.645287-645287

2021

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Longitudinal Metabolomics Profiling of Parkinson's Disease-Related α-Synuclein A53T Transgenic Mice

PloS one, 2015-08, Vol.10 (8), p.e0136612-e0136612

2015

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C9ORF72 GGGGCC Expanded Repeats Produce Splicing Dysregulation which Correlates with Disease Severity in Amyotrophic Lateral Sclerosis

PloS one, 2015-05, Vol.10 (5), p.e0127376

2015

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Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway

Molecular neurodegeneration, 2012-01, Vol.7 (1), p.2-2

2012

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Mitochondrial Complex 1 Activity Measured by Spectrophotometry Is Reduced across All Brain Regions in Ageing and More Specifically in Neurodegeneration

PloS one, 2016-06, Vol.11 (6), p.e0157405-e0157405

2016

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Essential role for autophagy protein VMP1 in maintaining neuronal homeostasis and preventing axonal degeneration

Cell death & disease, 2021-01, Vol.12 (1), p.116-116, Article 116

2021

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Phosphorylation of Ezrin/Radixin/Moesin Proteins by LRRK2 Promotes the Rearrangement of Actin Cytoskeleton in Neuronal Morphogenesis

The Journal of neuroscience, 2009-11, Vol.29 (44), p.13971-13980

2009

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Defective mitochondrial dynamics is an early event in skeletal muscle of an amyotrophic lateral sclerosis mouse model

PloS one, 2013-12, Vol.8 (12), p.e82112-e82112

2013

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The IkappaB kinase family phosphorylates the Parkinson's disease kinase LRRK2 at Ser935 and Ser910 during Toll-like receptor signaling

PloS one, 2012-06, Vol.7 (6), p.e39132

2012

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Astrocytic expression of Parkinson's disease-related A53T alpha-synuclein causes neurodegeneration in mice

Molecular brain, 2010-04, Vol.3 (1), p.12-12, Article 12

2010

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Nurr1Cd11bcre conditional knockout mice display inflammatory injury to nigrostriatal dopaminergic neurons

Glia, 2020-10, Vol.68 (10), p.2057-2069

2020

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Exposure to mitochondrial genotoxins and dopaminergic neurodegeneration in Caenorhabditis elegans

PloS one, 2014-12, Vol.9 (12), p.e114459

2014

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MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein

Human molecular genetics, 2013-02, Vol.22 (3), p.608-620

2013

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Abnormal cognition, sleep, EEG and brain metabolism in a novel knock-in Alzheimer mouse, PLB1

PloS one, 2011-11, Vol.6 (11), p.e27068-e27068

2011

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Low-level overexpression of wild type TDP-43 causes late-onset, progressive neurodegeneration and paralysis in mice

PloS one, 2022-02, Vol.17 (2), p.e0255710-e0255710

2022

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The spider effect: morphological and orienting classification of microglia in response to stimuli in vivo

PloS one, 2012-02, Vol.7 (2), p.e30763-e30763

2012

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Dendritic potassium channel dysfunction may contribute to dendrite degeneration in spinocerebellar ataxia type 1

PloS one, 2018-05, Vol.13 (5), p.e0198040-e0198040

2018

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Autophagy in neurodegenerative diseases: pathogenesis and therapy

Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2

Therapeutic Effect of Berberine on Huntington's Disease Transgenic Mouse Model

MicroRNA-206: a potential circulating biomarker candidate for amyotrophic lateral sclerosis

The essential role of transcription factor Pitx3 in preventing mesodiencephalic dopaminergic neurodegeneration and maintaining neuronal subtype identities during aging

Acute Hypoxia Induced an Imbalanced M1/M2 Activation of Microglia through NF-κB Signaling in Alzheimer's Disease Mice and Wild-Type Littermates

The Crucial Roles of Pitx3 in Midbrain Dopaminergic Neuron Development and Parkinson's Disease-Associated Neurodegeneration

Impaired inflammatory responses in murine Lrrk2-knockdown brain microglia

Connectivity and Functionality of the Globus Pallidus Externa Under Normal Conditions and Parkinson's Disease

Longitudinal Metabolomics Profiling of Parkinson's Disease-Related α-Synuclein A53T Transgenic Mice

C9ORF72 GGGGCC Expanded Repeats Produce Splicing Dysregulation which Correlates with Disease Severity in Amyotrophic Lateral Sclerosis

Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway

Mitochondrial Complex 1 Activity Measured by Spectrophotometry Is Reduced across All Brain Regions in Ageing and More Specifically in Neurodegeneration

Essential role for autophagy protein VMP1 in maintaining neuronal homeostasis and preventing axonal degeneration

Phosphorylation of Ezrin/Radixin/Moesin Proteins by LRRK2 Promotes the Rearrangement of Actin Cytoskeleton in Neuronal Morphogenesis

Defective mitochondrial dynamics is an early event in skeletal muscle of an amyotrophic lateral sclerosis mouse model

The IkappaB kinase family phosphorylates the Parkinson's disease kinase LRRK2 at Ser935 and Ser910 during Toll-like receptor signaling

Astrocytic expression of Parkinson's disease-related A53T alpha-synuclein causes neurodegeneration in mice

Nurr1Cd11bcre conditional knockout mice display inflammatory injury to nigrostriatal dopaminergic neurons

Exposure to mitochondrial genotoxins and dopaminergic neurodegeneration in Caenorhabditis elegans

MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein

Abnormal cognition, sleep, EEG and brain metabolism in a novel knock-in Alzheimer mouse, PLB1

Low-level overexpression of wild type TDP-43 causes late-onset, progressive neurodegeneration and paralysis in mice

The spider effect: morphological and orienting classification of microglia in response to stimuli in vivo

Dendritic potassium channel dysfunction may contribute to dendrite degeneration in spinocerebellar ataxia type 1

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