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On the Usefulness of Two Small-Scale In Vitro Setups in the Evaluation of Luminal Precipitation of Lipophilic Weak Bases in Early Formulation Development

Pharmaceutics, 2020-03, Vol.12 (3), p.272

2020

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Study of pH-dependent solubility of organic bases. Revisit of Henderson-Hasselbalch relationship

Analytica chimica acta, 2010-07, Vol.673 (1), p.40-46

2010

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Small-Scale Assays for Studying Dissolution of Pharmaceutical Cocrystals for Oral Administration

AAPS PharmSciTech, 2016-04, Vol.17 (2), p.245-251

2016

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On the usefulness of four in vitro methods in assessing the intraluminal performance of poorly soluble, ionisable compounds in the fasted state

European journal of pharmaceutical sciences, 2022-01, Vol.168, p.106034-106034, Article 106034

2022

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pH-Dependent Liquid–Liquid Phase Separation of Highly Supersaturated Solutions of Weakly Basic Drugs

Molecular pharmaceutics, 2015-07, Vol.12 (7), p.2365-2377

2015

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Biphasic drug release testing coupled with diffusing wave spectroscopy for mechanistic understanding of solid dispersion performance

European journal of pharmaceutical sciences, 2019-09, Vol.137, p.105001-105001, Article 105001

2019

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In vitro methods to assess drug precipitation in the fasted small intestine – a PEARRL review

Journal of pharmacy and pharmacology, 2019-04, Vol.71 (4), p.536-556

2019

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Combining biorelevant in vitro and in silico tools to simulate and better understand the in vivo performance of a nano-sized formulation of aprepitant in the fasted and fed states

European journal of pharmaceutical sciences, 2019-10, Vol.138, p.105031-105031, Article 105031

2019

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Developing an in vitro lipolysis model for real-time analysis of drug concentrations during digestion of lipid-based formulations

European journal of pharmaceutical sciences, 2024-03, Vol.194, p.106681-106681, Article 106681

2024

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Combining biorelevant in vitro and in silico tools to investigate the in vivo performance of the amorphous solid dispersion formulation of etravirine in the fed state

European journal of pharmaceutical sciences, 2020-06, Vol.149, p.105297, Article 105297

2020

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Novel Biphasic Lipolysis Method To Predict in Vivo Performance of Lipid-Based Formulations

Molecular pharmaceutics, 2020-09, Vol.17 (9), p.3342-3352

2020

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Oral biopharmaceutics tools: recent progress from partnership through the Pharmaceutical Education and Research with Regulatory Links collaboration

Journal of pharmacy and pharmacology, 2021-03, Vol.73 (4), p.437-446

2021

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pH-Induced Precipitation Behavior of Weakly Basic Compounds: Determination of Extent and Duration of Supersaturation Using Potentiometric Titration and Correlation to Solid State Properties

Pharmaceutical research, 2012-10, Vol.29 (10), p.2738-2753

2012

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Applying Computational Predictions of Biorelevant Solubility Ratio Upon Self-Emulsifying Lipid-Based Formulations Dispersion to Predict Dose Number

Journal of pharmaceutical sciences, 2021-01, Vol.110 (1), p.164-175

2021

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Effects of medicines used to treat gastrointestinal diseases on the pharmacokinetics of coadministered drugs: a PEARRL Review

Journal of pharmacy and pharmacology, 2019-04, Vol.71 (4), p.643-673

2019

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Diclofenac Solubility: Independent Determination of the Intrinsic Solubility of Three Crystal Forms

Journal of medicinal chemistry, 2007-03, Vol.50 (5), p.979-983

2007

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Acidity and Hydrophobicity of Several New Potential Antitubercular Drugs: Isoniazid and Benzimidazole Derivatives

Journal of chemical and engineering data, 2012-02, Vol.57 (2), p.330-338

2012

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Equilibrium versus kinetic measurements of aqueous solubility, and the ability of compounds to supersaturate in solution—a validation study

Journal of pharmaceutical sciences, 2006-06, Vol.95 (6), p.1298-1307

2006

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A new method for the reproducible generation of polymorphs: two forms of sulindac with very different solubilities

Journal of applied crystallography, 2007-04, Vol.40 (2), p.379-381

2007

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Physicochemical Properties of a New Multicomponent Cosolvent System for the pKa Determination of Poorly Soluble Pharmaceutical Compounds

Helvetica chimica acta, 2007-08, Vol.90 (8), p.1538-1553

2007

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The chemistry of multi-protic drugs Part 1: A potentiometric, multi-wavelength UV and NMR pH titrimetric study of the micro-speciation of SKI-606

Journal of pharmaceutical and biomedical analysis, 2008-06, Vol.47 (2), p.303-311

2008

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On the usefulness of four in vitro methodologies in screening for product related differences in tacrolimus exposure after oral administration of amorphous solid dispersions with modified release characteristics in the fasted state

Journal of drug delivery science and technology, 2022-03, Vol.69, p.102990, Article 102990

2022

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Structure-Lipophilicity Relationships of Neutral and Protonated β-Blockers, Part I, Intra- and Intermolecular Effects in Isotropic Solvent Systems

Helvetica chimica acta, 1999-08, Vol.82 (8), p.1211-1222

1999

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pH-Induced Precipitation Behavior of Weakly Basic Compounds: Determination of Extent and Duration of Supersaturation Using Potentiometric Titration and Correlation to Solid State Properties : Physicochemical Interactions in Solid Dosage Forms

Pharmaceutical research, 2012, Vol.29 (10), p.2738-2753

2012

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The chemistry of multi-protic drugs

Journal of pharmaceutical and biomedical analysis, 2008-06, Vol.47 (2), p.303-311

2008

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On the Usefulness of Two Small-Scale In Vitro Setups in the Evaluation of Luminal Precipitation of Lipophilic Weak Bases in Early Formulation Development

Study of pH-dependent solubility of organic bases. Revisit of Henderson-Hasselbalch relationship

Small-Scale Assays for Studying Dissolution of Pharmaceutical Cocrystals for Oral Administration

On the usefulness of four in vitro methods in assessing the intraluminal performance of poorly soluble, ionisable compounds in the fasted state

pH-Dependent Liquid–Liquid Phase Separation of Highly Supersaturated Solutions of Weakly Basic Drugs

Biphasic drug release testing coupled with diffusing wave spectroscopy for mechanistic understanding of solid dispersion performance

In vitro methods to assess drug precipitation in the fasted small intestine – a PEARRL review

Combining biorelevant in vitro and in silico tools to simulate and better understand the in vivo performance of a nano-sized formulation of aprepitant in the fasted and fed states

Developing an in vitro lipolysis model for real-time analysis of drug concentrations during digestion of lipid-based formulations

Combining biorelevant in vitro and in silico tools to investigate the in vivo performance of the amorphous solid dispersion formulation of etravirine in the fed state

Novel Biphasic Lipolysis Method To Predict in Vivo Performance of Lipid-Based Formulations

Oral biopharmaceutics tools: recent progress from partnership through the Pharmaceutical Education and Research with Regulatory Links collaboration

pH-Induced Precipitation Behavior of Weakly Basic Compounds: Determination of Extent and Duration of Supersaturation Using Potentiometric Titration and Correlation to Solid State Properties

Applying Computational Predictions of Biorelevant Solubility Ratio Upon Self-Emulsifying Lipid-Based Formulations Dispersion to Predict Dose Number

Effects of medicines used to treat gastrointestinal diseases on the pharmacokinetics of coadministered drugs: a PEARRL Review

Diclofenac Solubility: Independent Determination of the Intrinsic Solubility of Three Crystal Forms

Acidity and Hydrophobicity of Several New Potential Antitubercular Drugs: Isoniazid and Benzimidazole Derivatives

Equilibrium versus kinetic measurements of aqueous solubility, and the ability of compounds to supersaturate in solution—a validation study

A new method for the reproducible generation of polymorphs: two forms of sulindac with very different solubilities

Physicochemical Properties of a New Multicomponent Cosolvent System for the pKa Determination of Poorly Soluble Pharmaceutical Compounds

The chemistry of multi-protic drugs Part 1: A potentiometric, multi-wavelength UV and NMR pH titrimetric study of the micro-speciation of SKI-606

On the usefulness of four in vitro methodologies in screening for product related differences in tacrolimus exposure after oral administration of amorphous solid dispersions with modified release characteristics in the fasted state

Structure-Lipophilicity Relationships of Neutral and Protonated β-Blockers, Part I, Intra- and Intermolecular Effects in Isotropic Solvent Systems

pH-Induced Precipitation Behavior of Weakly Basic Compounds: Determination of Extent and Duration of Supersaturation Using Potentiometric Titration and Correlation to Solid State Properties : Physicochemical Interactions in Solid Dosage Forms

The chemistry of multi-protic drugs

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