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Drug transporters in the lung—do they play a role in the biopharmaceutics of inhaled drugs?

Journal of pharmaceutical sciences, 2010-05, Vol.99 (5), p.2240-2255

Bosquillon, Cynthia

2010

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A Comparison of Drug Transport in Pulmonary Absorption Models: Isolated Perfused rat Lungs, Respiratory Epithelial Cell Lines and Primary Cell Culture

Pharmaceutical research, 2017-12, Vol.34 (12), p.2532-2540

2017

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PEGylation of paclitaxel largely improves its safety and anti-tumor efficacy following pulmonary delivery in a mouse model of lung carcinoma

Journal of controlled release, 2016-10, Vol.239, p.62-71

2016

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Evaluating the effects of processing parameters on budesonide nanocrystals prepared by nanomilling

British Journal of Pharmacy, 2022-11, Vol.7 (2), p.S1-S2

2022

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Synthesis and In Vitro Evaluation of Polyethylene Glycol-Paclitaxel Conjugates for Lung Cancer Therapy

Pharmaceutical research, 2016-07, Vol.33 (7), p.1671-1681

2016

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Development of an In Vitro System to Study the Interactions of Aerosolized Drugs with Pulmonary Mucus

Pharmaceutics, 2020-02, Vol.12 (2), p.145

2020

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In-vitro respiratory drug absorption models possess nominal functional P-glycoprotein activity

Journal of pharmacy and pharmacology, 2009-03, Vol.61 (3), p.293-301

2009

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Contribution of the Alkylquinolone Quorum-Sensing System to the Interaction of Pseudomonas aeruginosa With Bronchial Epithelial Cells

Frontiers in microbiology, 2018-12, Vol.9, p.3018-3018

2018

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Aerosolization properties, surface composition and physical state of spray-dried protein powders

Journal of controlled release, 2004-10, Vol.99 (3), p.357-367

2004

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Corrigendum: Contribution of the Alkylquinolone Quorum-Sensing System to the Interaction of Pseudomonas Aeruginosa With Bronchial Epithelial Cells

Frontiers in microbiology, 2019-02, Vol.10, p.314-314

2019

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In vitro investigation on the impact of airway mucus on drug dissolution and absorption at the air-epithelium interface in the lungs

European journal of pharmaceutics and biopharmaceutics, 2019-08, Vol.141, p.210-220

2019

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Biodistribution and elimination pathways of PEGylated recombinant human deoxyribonuclease I after pulmonary delivery in mice

Journal of controlled release, 2021-01, Vol.329, p.1054-1065

2021

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Ipratropium is ‘luminally recycled’ by an inter-play between apical uptake and efflux transporters in Calu-3 bronchial epithelial cell layers

International journal of pharmaceutics, 2017-10, Vol.532 (1), p.328-336

2017

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Comparison of particle sizing techniques in the case of inhalation dry powders

Journal of pharmaceutical sciences, 2001-12, Vol.90 (12), p.2032-2041

2001

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PEGylation of recombinant human deoxyribonuclease I decreases its transport across lung epithelial cells and uptake by macrophages

International journal of pharmaceutics, 2021-01, Vol.593, p.120107-120107, Article 120107

2021

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Design, Synthesis, and Evaluation of Lung-Retentive Prodrugs for Extending the Lung Tissue Retention of Inhaled Drugs

Journal of medicinal chemistry, 2022-07, Vol.65 (14), p.9802-9818

2022

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Interactions of PEO–PPO–PEO block copolymers with lipid membranes: a computational and experimental study linking membrane lysis with polymer structure

Soft matter, 2012-07, Vol.8 (25), p.6744-6754

2012

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Exploring the enzymatic degradation of poly(glycerol adipate)

European journal of pharmaceutics and biopharmaceutics, 2019-09, Vol.142, p.377-386

2019

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Comparison of Gene Transfection and Cytotoxicity Mechanisms of Linear Poly Polyplexes

Pharmaceutical research, 2018-04, Vol.35 (4)

2018

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Dry-powder formulations of non-covalent protein complexes with linear or miktoarm copolymers for pulmonary delivery

International journal of pharmaceutics, 2018-04, Vol.540 (1-2), p.78-88

2018

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Comparison of Gene Transfection and Cytotoxicity Mechanisms of Linear Poly(amidoamine) and Branched Poly(ethyleneimine) Polyplexes

Pharmaceutical research, 2018-04, Vol.35 (4), p.86-12, Article 86

2018

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Effect of polymer topology on non-covalent polymer–protein complexation: miktoarm versus linear mPEG-poly(glutamic acid) copolymers

Polymer chemistry, 2017-04, Vol.8 (14), p.2210-2220

2017

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Study on Significance of Receptor Targeting in Killing of Intracellular Bacteria with Membrane‐Impermeable Antibiotics

Advanced therapeutics, 2021-12, Vol.4 (12), p.n/a

2021

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In-vitro respiratory drug absorption models possess nominal functional P-glycoprotein activity

Journal of pharmacy and pharmacology, 2009-03, Vol.61 (3), p.293-301

2009

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Relationship between the Affinity of PEO-PPO-PEO Block Copolymers for Biological Membranes and Their Cellular Effects

Pharmaceutical research, 2012-07, Vol.29 (7), p.1908-1918

2012

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Drug transporters in the lung—do they play a role in the biopharmaceutics of inhaled drugs?

A Comparison of Drug Transport in Pulmonary Absorption Models: Isolated Perfused rat Lungs, Respiratory Epithelial Cell Lines and Primary Cell Culture

PEGylation of paclitaxel largely improves its safety and anti-tumor efficacy following pulmonary delivery in a mouse model of lung carcinoma

Evaluating the effects of processing parameters on budesonide nanocrystals prepared by nanomilling

Synthesis and In Vitro Evaluation of Polyethylene Glycol-Paclitaxel Conjugates for Lung Cancer Therapy

Development of an In Vitro System to Study the Interactions of Aerosolized Drugs with Pulmonary Mucus

In-vitro respiratory drug absorption models possess nominal functional P-glycoprotein activity

Contribution of the Alkylquinolone Quorum-Sensing System to the Interaction of Pseudomonas aeruginosa With Bronchial Epithelial Cells

Aerosolization properties, surface composition and physical state of spray-dried protein powders

Corrigendum: Contribution of the Alkylquinolone Quorum-Sensing System to the Interaction of Pseudomonas Aeruginosa With Bronchial Epithelial Cells

In vitro investigation on the impact of airway mucus on drug dissolution and absorption at the air-epithelium interface in the lungs

Biodistribution and elimination pathways of PEGylated recombinant human deoxyribonuclease I after pulmonary delivery in mice

Ipratropium is ‘luminally recycled’ by an inter-play between apical uptake and efflux transporters in Calu-3 bronchial epithelial cell layers

Comparison of particle sizing techniques in the case of inhalation dry powders

PEGylation of recombinant human deoxyribonuclease I decreases its transport across lung epithelial cells and uptake by macrophages

Design, Synthesis, and Evaluation of Lung-Retentive Prodrugs for Extending the Lung Tissue Retention of Inhaled Drugs

Interactions of PEO–PPO–PEO block copolymers with lipid membranes: a computational and experimental study linking membrane lysis with polymer structure

Exploring the enzymatic degradation of poly(glycerol adipate)

Comparison of Gene Transfection and Cytotoxicity Mechanisms of Linear Poly Polyplexes

Dry-powder formulations of non-covalent protein complexes with linear or miktoarm copolymers for pulmonary delivery

Comparison of Gene Transfection and Cytotoxicity Mechanisms of Linear Poly(amidoamine) and Branched Poly(ethyleneimine) Polyplexes

Effect of polymer topology on non-covalent polymer–protein complexation: miktoarm versus linear mPEG-poly(glutamic acid) copolymers

Study on Significance of Receptor Targeting in Killing of Intracellular Bacteria with Membrane‐Impermeable Antibiotics

In-vitro respiratory drug absorption models possess nominal functional P-glycoprotein activity

Relationship between the Affinity of PEO-PPO-PEO Block Copolymers for Biological Membranes and Their Cellular Effects

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