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Precision targeting of autoantigen-specific B cells in muscle-specific tyrosine kinase myasthenia gravis with chimeric autoantibody receptor T cells

Nature biotechnology, 2023-09, Vol.41 (9), p.1229-1238

2023

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The very stable lentiviral vector

Molecular therapy. Methods & clinical development, 2024-03, Vol.32 (1), p.101223

2024

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Gene Transfer in Humans Using a Conditionally Replicating Lentiviral Vector

Proceedings of the National Academy of Sciences - PNAS, 2006-11, Vol.103 (46), p.17372-17377

2006

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Chimeric Receptors Containing CD137 Signal Transduction Domains Mediate Enhanced Survival of T Cells and Increased Antileukemic Efficacy In Vivo

Molecular therapy, 2009-08, Vol.17 (8), p.1453-1464

2009

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Antisense-Mediated Inhibition of Human Immunodeficiency Virus (HIV) Replication by Use of an HIV Type 1-Based Vector Results in Severely Attenuated Mutants Incapable of Developing Resistance

Journal of Virology, 2004-07, Vol.78 (13), p.7079-7088

2004

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Systemic and local immunity following adoptive transfer of NY-ESO-1 SPEAR T cells in synovial sarcoma

Journal for immunotherapy of cancer, 2019-10, Vol.7 (1), p.276-276, Article 276

2019

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Long‐term safety and activity of NY-ESO‐1 SPEAR T cells after autologous stem cell transplant for myeloma

Blood advances, 2019-07, Vol.3 (13), p.2022-2034

2019

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Analysis of Lentiviral Vector Integration in HIV+ Study Subjects Receiving Autologous Infusions of Gene Modified CD4+ T Cells

Molecular therapy, 2009-05, Vol.17 (5), p.844-850

2009

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Interferon-γ-Mediated Site-Specific Clearance of Alphavirus from CNS Neurons

Science (American Association for the Advancement of Science), 2001-07, Vol.293 (5528), p.303-306

2001

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Regulatory considerations for novel gene therapy products : A review of the process leading to the first clinical lentiviral vector

Human gene therapy, 2005, Vol.16 (1), p.17-25

2005

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Efficient clinical scale gene modification via zinc finger nuclease-targeted disruption of the HIV co-receptor CCR5

Human gene therapy, 2013-03, Vol.24 (3), p.245

2013

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Efficient Lentiviral Vector-mediated Control of HIV-1 Replication in CD4 Lymphocytes from Diverse HIV Infected Patients Grouped According to CD4 Count and Viral Load

Molecular therapy, 2004-06, Vol.9 (6), p.902-913

2004

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Immune-mediated clearance of virus from the central nervous system

Microbes and Infection, 2003-04, Vol.5 (5), p.439-448

2003

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Inhibition of Simian/Human Immunodeficiency Virus Replication in CD4 T Cells Derived from Lentiviral-Transduced CD34 Hematopoietic Cells

Molecular therapy, 2005-12, Vol.12 (6), p.1157-1167

2005

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192. Deep Phenotyping of Manufactured Enhanced-Affinity NY-ESO-1-Specific T Cells Reveals a Pattern of Effector and Memory Programming That Correlates with Clinical Outcome in Observed Cancer Indications

Molecular therapy, 2016-05, Vol.24, p.S75-S75

2016

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Interferon-[Gamma]-Mediated Site-Specific Clearance of Alphavirus from CNS Neurons

Science (American Association for the Advancement of Science), 2001-07, Vol.293 (5528), p.303-303

2001

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Abstract 4575: Correlates of clinical response following autologous stem cell transplant and adoptive immunotherapy with engineered T cells expressing an affinity-enhanced T cell receptor in patients with mutliple myeloma

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.4575-4575

2013

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Lentivirus Vector Manufacturing

Concepts in Genetic Medicine, 2008, p.253-268

2008

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Precision targeting of autoantigen-specific B cells in muscle-specific tyrosine kinase myasthenia gravis with chimeric autoantibody receptor T cells

The very stable lentiviral vector

Gene Transfer in Humans Using a Conditionally Replicating Lentiviral Vector

Chimeric Receptors Containing CD137 Signal Transduction Domains Mediate Enhanced Survival of T Cells and Increased Antileukemic Efficacy In Vivo

Antisense-Mediated Inhibition of Human Immunodeficiency Virus (HIV) Replication by Use of an HIV Type 1-Based Vector Results in Severely Attenuated Mutants Incapable of Developing Resistance

Systemic and local immunity following adoptive transfer of NY-ESO-1 SPEAR T cells in synovial sarcoma

NY-ESO-1-specific TCR-engineered T cells mediate sustained antigen-specific antitumor effects in myeloma

Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma

Long‐term safety and activity of NY-ESO‐1 SPEAR T cells after autologous stem cell transplant for myeloma

Analysis of Lentiviral Vector Integration in HIV+ Study Subjects Receiving Autologous Infusions of Gene Modified CD4+ T Cells

Interferon-γ-Mediated Site-Specific Clearance of Alphavirus from CNS Neurons

Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1 c259T Cells in Synovial Sarcoma

Regulatory considerations for novel gene therapy products : A review of the process leading to the first clinical lentiviral vector

Efficient clinical scale gene modification via zinc finger nuclease-targeted disruption of the HIV co-receptor CCR5

Efficient Lentiviral Vector-mediated Control of HIV-1 Replication in CD4 Lymphocytes from Diverse HIV Infected Patients Grouped According to CD4 Count and Viral Load

Immune-mediated clearance of virus from the central nervous system

Inhibition of Simian/Human Immunodeficiency Virus Replication in CD4 T Cells Derived from Lentiviral-Transduced CD34 Hematopoietic Cells

Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1c259T Cells in Synovial Sarcoma

192. Deep Phenotyping of Manufactured Enhanced-Affinity NY-ESO-1-Specific T Cells Reveals a Pattern of Effector and Memory Programming That Correlates with Clinical Outcome in Observed Cancer Indications

Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1 c259 T Cells in Synovial Sarcoma

511. Enhanced-Affinity NY-ESO-1-Specific T Cells Exhibit Extended Functionality without Exhaustion in a Pattern of Effector and Memory Programming in Multiple Cancer Indications

Engineered T-Cells Expressing An HLA-Restricted Affinity-Enhanced TCR In Advanced Multiple Myeloma Patients Post Auto-SCT Engraft and Are Associated With Encouraging Post Auto-SCT Responses

Interferon-[Gamma]-Mediated Site-Specific Clearance of Alphavirus from CNS Neurons

Abstract 4575: Correlates of clinical response following autologous stem cell transplant and adoptive immunotherapy with engineered T cells expressing an affinity-enhanced T cell receptor in patients with mutliple myeloma

Lentivirus Vector Manufacturing

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