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Englerin A induces an acute inflammatory response and reveals lipid metabolism and ER stress as targetable vulnerabilities in renal cell carcinoma

PloS one, 2017-03, Vol.12 (3), p.e0172632

2017

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High Expression of CAI2, a 9p21-Embedded Long Noncoding RNA, Contributes to Advanced-Stage Neuroblastoma

Cancer research (Chicago, Ill.), 2014-07, Vol.74 (14), p.3753-3763

2014

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Renal cancer-selective Englerin A induces multiple mechanisms of cell death and autophagy

Journal of experimental & clinical cancer research, 2013-08, Vol.32 (1), p.57-57, Article 57

2013

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Evaluation of the pharmacophoric motif of the caged Garcinia xanthones

Organic & biomolecular chemistry, 2009-01, Vol.7 (23), p.4886-4894

2009

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A-ring oxygenation modulates the chemistry and bioactivity of caged Garcinia xanthones

Organic & biomolecular chemistry, 2013-05, Vol.11 (20), p.3341-3348

2013

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Formal Synthesis of (−)-Englerin A and Cytotoxicity Studies of Truncated Englerins

Chemistry, an Asian journal, 2012-05, Vol.7 (5), p.1052-1060

2012

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Chimeras of p14ARF and p16: functional hybrids with the ability to arrest growth

PloS one, 2014-02, Vol.9 (2), p.e88219-e88219

2014

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The synthetic caged garcinia xanthone cluvenone induces cell stress and apoptosis and has immune modulatory activity

Molecular cancer therapeutics, 2010-11, Vol.9 (11), p.2869-2878

2010

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Long-Term Follow-up of a Phase III Study of ch14.18 (Dinutuximab) + Cytokine Immunotherapy in Children with High-Risk Neuroblastoma: COG Study ANBL0032

Clinical cancer research, 2021-04, Vol.27 (8), p.2179-2189

2021

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Chemistry and Biology of the Caged Garcinia Xanthones

Chemistry : a European journal, 2010-09, Vol.16 (33), p.9944-9962

2010

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Abstract 2180: Drug-like inhibitors of SGK1: Discovery and optimization of low molecular weight fragment leads

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.2180-2180

2016

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The Ch14.18-GM-CSF Fusion Protein Is Effective at Mediating Antibody-dependent Cellular Cytotoxicity and Complement-dependent Cytotoxicity in Vitro

Clinical cancer research, 1999-12, Vol.5 (12), p.4259-4263

1999

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Long-term follow-up of a Phase III Study of ch14.18 (Dinutuximab) + Cytokine Immunotherapy in Children with High-risk Neuroblastoma: Children’s Oncology Group Study ANBL0032

Clinical cancer research, 2021-01, Vol.27 (8), p.2179-2189

2021

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Abstract 3219: Targeting lipid metabolism and ER stress in renal cell carcinoma by englerin A

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.3219-3219

2017

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Subcellular Localization and Activity of Gambogic Acid

Chembiochem : a European journal of chemical biology, 2012-05, Vol.13 (8), p.1191-1198

2012

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Universal Inactivation of Both p16 and p15 but not Downstream Components Is an Essential Event in the Pathogenesis of T-Cell Acute Lymphoblastic Leukemia

Clinical cancer research, 2000-04, Vol.6 (4), p.1219-1228

2000

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Abstract LB-16: Discovery of novel SGK1 inhibitors by a fragment-based approach: Generating patentable, chemically tractable and ligand efficient leads

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.LB-16-LB-16

2014

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High expression of CAI2, a 9p21-embedded long non-coding RNA, contributes to advanced stage neuroblastoma

Cancer research (Chicago, Ill.), 2014-07, Vol.74 (14), p.3753-3763

2014

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Cluvenone induces apoptosis via a direct target in mitochondria: a possible mechanism to circumvent chemo-resistance?

Investigational new drugs, 2012-10, Vol.30 (5), p.1841-1848

2012

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Erratum: renal cancer-selective Englerin A induces multiple mechanisms of cell death and autophagy

Journal of experimental & clinical cancer research, 2014-12, Vol.33 (1), p.95-95, Article 95

2014

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A-ring oxygenation modulates the chemistry and bioactivity of caged Garcinia xanthonesElectronic supplementary information (ESI) available: Experimental procedures for all reactions and biological assays and copies of 1H and 13C NMR spectra for compounds 3, 4 and 9-21. See DOI: 10.1039/c3ob40395e

2013-05

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Synthesis and evaluation of caged Garcinia xanthones

Organic & biomolecular chemistry, 2007-01, Vol.5 (3), p.494-500

2007

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Formal Synthesis of (-)-EnglerinA and Cytotoxicity Studies of Truncated Englerins

Chemistry, an Asian journal, 2012-05, Vol.7 (5), p.1052

2012

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Cover Picture: Chemistry and Biology of the Caged Garcinia Xanthones (Chem. Eur. J. 33/2010)

Chemistry : a European journal, 2010-09, Vol.16 (33), p.9925-9925

2010

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The histone deacetylase inhibitor AN-9 has selective toxicity to acute leukemia and drug-resistant primary leukemia and cancer cell lines

Blood, 2002-11, Vol.100 (9), p.3319-3324

2002

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Englerin A induces an acute inflammatory response and reveals lipid metabolism and ER stress as targetable vulnerabilities in renal cell carcinoma

High Expression of CAI2, a 9p21-Embedded Long Noncoding RNA, Contributes to Advanced-Stage Neuroblastoma

Renal cancer-selective Englerin A induces multiple mechanisms of cell death and autophagy

Evaluation of the pharmacophoric motif of the caged Garcinia xanthones

A-ring oxygenation modulates the chemistry and bioactivity of caged Garcinia xanthones

Formal Synthesis of (−)-Englerin A and Cytotoxicity Studies of Truncated Englerins

Chimeras of p14ARF and p16: functional hybrids with the ability to arrest growth

The synthetic caged garcinia xanthone cluvenone induces cell stress and apoptosis and has immune modulatory activity

Long-Term Follow-up of a Phase III Study of ch14.18 (Dinutuximab) + Cytokine Immunotherapy in Children with High-Risk Neuroblastoma: COG Study ANBL0032

Chemistry and Biology of the Caged Garcinia Xanthones

Abstract 2180: Drug-like inhibitors of SGK1: Discovery and optimization of low molecular weight fragment leads

The Ch14.18-GM-CSF Fusion Protein Is Effective at Mediating Antibody-dependent Cellular Cytotoxicity and Complement-dependent Cytotoxicity in Vitro

Long-term follow-up of a Phase III Study of ch14.18 (Dinutuximab) + Cytokine Immunotherapy in Children with High-risk Neuroblastoma: Children’s Oncology Group Study ANBL0032

Abstract 3219: Targeting lipid metabolism and ER stress in renal cell carcinoma by englerin A

Subcellular Localization and Activity of Gambogic Acid

Universal Inactivation of Both p16 and p15 but not Downstream Components Is an Essential Event in the Pathogenesis of T-Cell Acute Lymphoblastic Leukemia

Abstract LB-16: Discovery of novel SGK1 inhibitors by a fragment-based approach: Generating patentable, chemically tractable and ligand efficient leads

High expression of CAI2, a 9p21-embedded long non-coding RNA, contributes to advanced stage neuroblastoma

Cluvenone induces apoptosis via a direct target in mitochondria: a possible mechanism to circumvent chemo-resistance?

Erratum: renal cancer-selective Englerin A induces multiple mechanisms of cell death and autophagy

A-ring oxygenation modulates the chemistry and bioactivity of caged Garcinia xanthonesElectronic supplementary information (ESI) available: Experimental procedures for all reactions and biological assays and copies of 1H and 13C NMR spectra for compounds 3, 4 and 9-21. See DOI: 10.1039/c3ob40395e

Synthesis and evaluation of caged Garcinia xanthones

Formal Synthesis of (-)-EnglerinA and Cytotoxicity Studies of Truncated Englerins

Cover Picture: Chemistry and Biology of the Caged Garcinia Xanthones (Chem. Eur. J. 33/2010)

The histone deacetylase inhibitor AN-9 has selective toxicity to acute leukemia and drug-resistant primary leukemia and cancer cell lines

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