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Modeling of Tumor Growth Incorporating the Effects of Necrosis and the Effect of Bevacizumab

Complexity (New York, N.Y.), 2017-01, Vol.2017, p.1-10

2017

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Simulations of tumor growth and response to immunotherapy by coupling a spatial agent-based model with a whole-patient quantitative systems pharmacology model

PLoS computational biology, 2022-07, Vol.18 (7), p.e1010254-e1010254

2022

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Integrated computational and in vivo models reveal Key Insights into macrophage behavior during bone healing

PLoS computational biology, 2022-05, Vol.18 (5), p.e1009839-e1009839

2022

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An Integrated Computational Model of the Bone Microenvironment in Bone-Metastatic Prostate Cancer

Cancer research (Chicago, Ill.), 2014-05, Vol.74 (9), p.2391-2401

2014

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Computational modeling reveals a key role for polarized myeloid cells in controlling osteoclast activity during bone injury repair

Scientific reports, 2021-03, Vol.11 (1), p.6055-6055, Article 6055

2021

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Hybrid Automata Library: A flexible platform for hybrid modeling with real-time visualization

PLoS computational biology, 2020-03, Vol.16 (3), p.e1007635-e1007635

2020

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Exploiting Evolution To Treat Drug Resistance: Combination Therapy and the Double Bind

Molecular pharmaceutics, 2012-04, Vol.9 (4), p.914-921

2012

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The bone ecosystem facilitates multiple myeloma relapse and the evolution of heterogeneous drug resistant disease

Nature communications, 2024-03, Vol.15 (1), p.2458-2458

2024

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A survey of open questions in adaptive therapy: Bridging mathematics and clinical translation

eLife, 2023-03, Vol.12

2023

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Evolutionary emergence of angiogenesis in avascular tumors using a spatial public goods game

PloS one, 2017-04, Vol.12 (4), p.e0175063-e0175063

2017

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Selection-driven tumor evolution with public goods leads to patterns of clonal expansion consistent with neutral growth

iScience, 2021-01, Vol.24 (1), p.101901-101901, Article 101901

2021

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What Is the Storage Effect, Why Should It Occur in Cancers, and How Can It Inform Cancer Therapy?

Cancer control, 2020-07, Vol.27 (3), p.1073274820941968

2020

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The Evolutionary Ecology of Dormancy in Nature and in Cancer

Frontiers in ecology and evolution, 2021-07, Vol.9

2021

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Invasion and proliferation kinetics in enhancing gliomas predict IDH1 mutation status

Neuro-oncology (Charlottesville, Va.), 2014-06, Vol.16 (6), p.779-786

2014

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Evolutionary game theory: molecules as players

Molecular bioSystems, 2014-12, Vol.1 (12), p.366-374

2014

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A Network Biology Approach Identifies Molecular Cross-Talk between Normal Prostate Epithelial and Prostate Carcinoma Cells

PLoS computational biology, 2016-04, Vol.12 (4), p.e1004884-e1004884

2016

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Preconditioning-Like Properties of Short-Term Hypothermia in Isolated Perfused Rat Liver (IPRL) System

International journal of molecular sciences, 2018-03, Vol.19 (4), p.1023

2018

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Microenvironmental variables must influence intrinsic phenotypic parameters of cancer stem cells to affect tumourigenicity

PLoS computational biology, 2014-01, Vol.10 (1), p.e1003433

2014

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Bifurcation mechanism design: From optimal flat taxes to better cancer treatments

Games, 2018-06, Vol.9 (2), p.1-38

2018

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Quantification and Optimization of Standard-of-Care Therapy to Delay the Emergence of Resistant Bone Metastatic Prostate Cancer

Cancers, 2021-02, Vol.13 (4), p.677

2021

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Coexistence of “Cream Skimmer” and “Crumb Picker” Phenotypes in Nature and in Cancer

Frontiers in ecology and evolution, 2021-09, Vol.9

2021

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IDENTIFICATION AND CLASSIFICATION OF MORPHOLOGICAL PHENOTYPES IN NATURE AND IN CANCER

Journal of pathology informatics, 2022, Vol.13, p.100056, Article 100056

2022

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The evolution of robust development and homeostasis in artificial organisms

PLoS computational biology, 2008-03, Vol.4 (3), p.e1000030-e1000030

2008

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Fractionated follow-up chemotherapy delays the onset of resistance in bone metastatic prostate cancer

Games, 2018-06, Vol.9 (2), p.1-10

2018

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Modeling Osteocyte Network Formation: Healthy and Cancerous Environments

Frontiers in bioengineering and biotechnology, 2020-07, Vol.8, p.757-757

2020

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Modeling of Tumor Growth Incorporating the Effects of Necrosis and the Effect of Bevacizumab

Simulations of tumor growth and response to immunotherapy by coupling a spatial agent-based model with a whole-patient quantitative systems pharmacology model

Integrated computational and in vivo models reveal Key Insights into macrophage behavior during bone healing

An Integrated Computational Model of the Bone Microenvironment in Bone-Metastatic Prostate Cancer

Computational modeling reveals a key role for polarized myeloid cells in controlling osteoclast activity during bone injury repair

Hybrid Automata Library: A flexible platform for hybrid modeling with real-time visualization

Exploiting Evolution To Treat Drug Resistance: Combination Therapy and the Double Bind

The bone ecosystem facilitates multiple myeloma relapse and the evolution of heterogeneous drug resistant disease

A survey of open questions in adaptive therapy: Bridging mathematics and clinical translation

Evolutionary emergence of angiogenesis in avascular tumors using a spatial public goods game

Selection-driven tumor evolution with public goods leads to patterns of clonal expansion consistent with neutral growth

What Is the Storage Effect, Why Should It Occur in Cancers, and How Can It Inform Cancer Therapy?

The Evolutionary Ecology of Dormancy in Nature and in Cancer

Invasion and proliferation kinetics in enhancing gliomas predict IDH1 mutation status

Evolutionary game theory: molecules as players

A Network Biology Approach Identifies Molecular Cross-Talk between Normal Prostate Epithelial and Prostate Carcinoma Cells

Preconditioning-Like Properties of Short-Term Hypothermia in Isolated Perfused Rat Liver (IPRL) System

Microenvironmental variables must influence intrinsic phenotypic parameters of cancer stem cells to affect tumourigenicity

Bifurcation mechanism design: From optimal flat taxes to better cancer treatments

Quantification and Optimization of Standard-of-Care Therapy to Delay the Emergence of Resistant Bone Metastatic Prostate Cancer

Coexistence of “Cream Skimmer” and “Crumb Picker” Phenotypes in Nature and in Cancer

IDENTIFICATION AND CLASSIFICATION OF MORPHOLOGICAL PHENOTYPES IN NATURE AND IN CANCER

The evolution of robust development and homeostasis in artificial organisms

Fractionated follow-up chemotherapy delays the onset of resistance in bone metastatic prostate cancer

Modeling Osteocyte Network Formation: Healthy and Cancerous Environments

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