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CAR T Cell Therapy for Solid Tumors

Annual review of medicine, 2017-01, Vol.68, p.139

2017

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CAR T cell therapy for patients with solid tumours: key lessons to learn and unlearn

Nature reviews. Clinical oncology, 2024-01, Vol.21 (1), p.47-66

Albelda, Steven M

2024

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Mesothelin-targeted CAR-T cell therapy for solid tumors

Expert opinion on biological therapy, 2021-04, Vol.21 (4), p.473-486

2021

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Tumor-associated neutrophils: friend or foe?

Carcinogenesis (New York), 2012-05, Vol.33 (5), p.949-955

2012

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Transcriptomic analysis comparing tumor-associated neutrophils with granulocytic myeloid-derived suppressor cells and normal neutrophils

PloS one, 2012-02, Vol.7 (2), p.e31524-e31524

2012

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Novel therapies for malignant pleural mesothelioma

The lancet oncology, 2018-03, Vol.19 (3), p.e161-e172

2018

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Origin and Role of a Subset of Tumor-Associated Neutrophils with Antigen-Presenting Cell Features in Early-Stage Human Lung Cancer

Cancer cell, 2016-07, Vol.30 (1), p.120-135

2016

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Asbestos Induces Oxidative Stress and Activation of Nrf2 Signaling in Murine Macrophages: Chemopreventive Role of the Synthetic Lignan Secoisolariciresinol Diglucoside (LGM2605)

International journal of molecular sciences, 2016-03, Vol.17 (3), p.322-322

2016

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Chimeric antigen receptor T-cell therapy for solid tumors

Molecular therapy. Oncolytics, 2016, Vol.3 (C), p.16006-16006, Article 16006

2016

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Tumor-Promoting Desmoplasia Is Disrupted by Depleting FAP-Expressing Stromal Cells

Cancer research (Chicago, Ill.), 2015-07, Vol.75 (14), p.2800-2810

2015

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CAR T cells produced in vivo to treat cardiac injury

Science (American Association for the Advancement of Science), 2022-01, Vol.375 (6576), p.91-96

2022

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Intraoperative Near-Infrared Imaging Can Identify Pulmonary Nodules

The Annals of thoracic surgery, 2014-10, Vol.98 (4), p.1223-1230

2014

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Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response

Journal of Immunology, 2007-07, Vol.179 (2), p.977-983

2007

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Neutrophils recruit regulatory T‐cells into tumors via secretion of CCL17—A new mechanism of impaired antitumor immunity

International journal of cancer, 2014-09, Vol.135 (5), p.1178-1186

2014

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Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T Cells

Immunity (Cambridge, Mass.), 2018-05, Vol.48 (5), p.1029-1045.e5

2018

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Targeting cardiac fibrosis with engineered T cells

Nature (London), 2019-09, Vol.573 (7774), p.430-433

2019

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Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer

The Journal of clinical investigation, 2014-12, Vol.124 (12), p.5466-5480

2014

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Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: “N1” versus “N2” TAN

Cancer cell, 2009-09, Vol.16 (3), p.183-194

2009

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Urinary volatile compounds as biomarkers for lung cancer: a proof of principle study using odor signatures in mouse models of lung cancer

PloS one, 2010-01, Vol.5 (1), p.e8819-e8819

2010

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The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivo

Nature immunology, 2011-08, Vol.12 (8), p.761

2011

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Phase I Study of Lentiviral-Transduced Chimeric Antigen Receptor-Modified T Cells Recognizing Mesothelin in Advanced Solid Cancers

Molecular therapy, 2019-11, Vol.27 (11), p.1919-1929

2019

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Gemcitabine Selectively Eliminates Splenic Gr-1+/CD11b+ Myeloid Suppressor Cells in Tumor-Bearing Animals and Enhances Antitumor Immune Activity

Clinical cancer research, 2005-09, Vol.11 (18), p.6713-6721

2005

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Mouse versus Human Neutrophils in Cancer: A Major Knowledge Gap

Trends in cancer, 2017-02, Vol.3 (2), p.149-160

2017

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Intra-tumoral delivery of CXCL11 via a vaccinia virus, but not by modified T cells, enhances the efficacy of adoptive T cell therapy and vaccines

Oncoimmunology, 2018-03, Vol.7 (3), p.e1395997-e1395997

2018

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Human tumor-associated monocytes/macrophages and their regulation of T cell responses in early-stage lung cancer

Science translational medicine, 2019-02, Vol.11 (479)

2019

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CAR T Cell Therapy for Solid Tumors

CAR T cell therapy for patients with solid tumours: key lessons to learn and unlearn

Mesothelin-targeted CAR-T cell therapy for solid tumors

Tumor-associated neutrophils: friend or foe?

Transcriptomic analysis comparing tumor-associated neutrophils with granulocytic myeloid-derived suppressor cells and normal neutrophils

Novel therapies for malignant pleural mesothelioma

Origin and Role of a Subset of Tumor-Associated Neutrophils with Antigen-Presenting Cell Features in Early-Stage Human Lung Cancer

Asbestos Induces Oxidative Stress and Activation of Nrf2 Signaling in Murine Macrophages: Chemopreventive Role of the Synthetic Lignan Secoisolariciresinol Diglucoside (LGM2605)

Chimeric antigen receptor T-cell therapy for solid tumors

Tumor-Promoting Desmoplasia Is Disrupted by Depleting FAP-Expressing Stromal Cells

CAR T cells produced in vivo to treat cardiac injury

Intraoperative Near-Infrared Imaging Can Identify Pulmonary Nodules

Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response

Neutrophils recruit regulatory T‐cells into tumors via secretion of CCL17—A new mechanism of impaired antitumor immunity

Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T Cells

Targeting cardiac fibrosis with engineered T cells

Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer

Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: “N1” versus “N2” TAN

Urinary volatile compounds as biomarkers for lung cancer: a proof of principle study using odor signatures in mouse models of lung cancer

The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivo

Phase I Study of Lentiviral-Transduced Chimeric Antigen Receptor-Modified T Cells Recognizing Mesothelin in Advanced Solid Cancers

Gemcitabine Selectively Eliminates Splenic Gr-1+/CD11b+ Myeloid Suppressor Cells in Tumor-Bearing Animals and Enhances Antitumor Immune Activity

Mouse versus Human Neutrophils in Cancer: A Major Knowledge Gap

Intra-tumoral delivery of CXCL11 via a vaccinia virus, but not by modified T cells, enhances the efficacy of adoptive T cell therapy and vaccines

Human tumor-associated monocytes/macrophages and their regulation of T cell responses in early-stage lung cancer

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