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Discovery of PF-00217830: Aryl piperazine napthyridinones as D₂ partial agonists for schizophrenia and bipolar disorder

Bioorganic & medicinal chemistry letters, 2011-05, Vol.21 (9), p.2621-2625

2011

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Affinity for Dopamine D2, D3, and D4 Receptors of 2-Aminotetralins. Relevance of D2 Agonist Binding for Determination of Receptor Subtype Selectivity

Journal of medicinal chemistry, 1996-10, Vol.39 (21), p.4233-4237

1996

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A Series of 6- and 7-Piperazinyl- and -Piperidinylmethylbenzoxazinones with Dopamine D4 Antagonist Activity: Discovery of a Potential Atypical Antipsychotic Agent

Journal of medicinal chemistry, 1999-12, Vol.42 (25), p.5181-5187

1999

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Discovery of PF-00217830: Aryl piperazine napthyridinones as D 2 partial agonists for schizophrenia and bipolar disorder

Bioorganic & medicinal chemistry letters, 2011-05, Vol.21 (9), p.2621-2625

2011

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Aryl 1-But-3-ynyl-4-phenyl-1,2,3,6-tetrahydropyridines as Potential Antipsychotic Agents: Synthesis and Structure−Activity Relationships

Journal of medicinal chemistry, 1996-08, Vol.39 (16), p.3179-3187

1996

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Design and Structure-Activity Relationships of C-Terminal Cyclic Neurotensin Fragment Analogs

Journal of medicinal chemistry, 1995-01, Vol.38 (2), p.249-257

1995

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3-Arylimino-2-indolones Are Potent and Selective Galanin GAL3 Receptor Antagonists

Journal of medicinal chemistry, 2006-06, Vol.49 (13), p.3757-3758

2006

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Substituted [(4-Phenylpiperazinyl)- methyl]benzamides: Selective Dopamine D4 Agonists

Journal of medicinal chemistry, 1997-06, Vol.40 (12), p.1771-1772

1997

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Discovery of PF-00217830: Aryl piperazine napthyridinones as D sub(2 partial agonists for schizophrenia and bipolar disorder)

Bioorganic & medicinal chemistry letters, 2011-05, Vol.21 (9), p.2621-2625

2011

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Pyrazolo[1,5-a]pyrimidine CRF-1 receptor antagonists

Bioorganic & medicinal chemistry letters, 1998-08, Vol.8 (16), p.2067-2070

1998

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Substituted [(4-Phenylpiperazinyl)- methyl]benzamides: Selective Dopamine D 4 Agonists

Journal of medicinal chemistry, 1997-06, Vol.40 (12), p.1771-1772

1997

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3-Arylimino-2-indolones Are Potent and Selective Galanin GAL 3 Receptor Antagonists

Journal of medicinal chemistry, 2006-06, Vol.49 (13), p.3757-3758

2006

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3-arylimino-2-indolones are potent and selective galanin GAL3receptor antagonists

Journal of medicinal chemistry, 2006, Vol.49 (13), p.3757-3758

2006

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Affinity for Dopamine D 2 , D 3 , and D 4 Receptors of 2-Aminotetralins. Relevance of D 2 Agonist Binding for Determination of Receptor Subtype Selectivity

Journal of medicinal chemistry, 1996-10, Vol.39 (21), p.4233-4237

1996

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GBR12909 antagonizes the ability of cocaine to elevate extracellular levels of dopamine

Pharmacology, biochemistry and behavior, 1991-10, Vol.40 (2), p.387-397

1991

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The discovery of PD 89211 and related compounds: Selective dopamine D4 receptor antagonists

Progress in neuro-psychopharmacology & biological psychiatry, 2002-02, Vol.26 (2), p.219-226

2002

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Aminopyrimidines with High Affinity for Both Serotonin and Dopamine Receptors

Journal of medicinal chemistry, 1998-02, Vol.41 (5), p.760-771

1998

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Identification of a GBR12935 homolog, LR1111, which is over 4,000-fold selective for the dopamine transporter, relative to serotonin and norepinephrine transporters

Synapse (New York, N.Y.), 1993-05, Vol.14 (1), p.34-39

1993

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Serotonin modulation of pain responsiveness in the aged rat

Pharmacology, biochemistry and behavior, 1994-06, Vol.48 (2), p.411-416

1994

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Characterization of binding of [ 3H]PD 128907, A selective Dopamine D 3 receptor agonist ligand, to CHO-K1 cells

Life sciences (1973), 1995-09, Vol.57 (15), p.1401-1410

1995

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Characterization of binding of [3H]PD 128907, a selective dopamine D3 receptor agonist ligand, to CHO-K1 cells

Life sciences (1973), 1995-09, Vol.57 (15), p.1401-1410

1995

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Novel cyclohexyl amides as potent and selective D 3 dopamine receptor ligands

Bioorganic & medicinal chemistry letters, 1997-09, Vol.7 (18), p.2403-2408

1997

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Novel cyclohexyl amides as potent and selective D3 dopamine receptor ligands

Bioorganic & medicinal chemistry letters, 1997-09, Vol.7 (18), p.2403-2408

1997

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Behavioral and neurochemical changes in the dopaminergic system after repeated cocaine administration

Molecular neurobiology, 1995-08, Vol.11 (1-3), p.55-66

1995

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Pharmacological characterization of PD 152255, a novel dimeric benzimidazole dopamine D3 antagonist

Pharmacology, biochemistry and behavior, 1998-02, Vol.59 (2), p.487-493

1998

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Discovery of PF-00217830: Aryl piperazine napthyridinones as D₂ partial agonists for schizophrenia and bipolar disorder

Affinity for Dopamine D2, D3, and D4 Receptors of 2-Aminotetralins. Relevance of D2 Agonist Binding for Determination of Receptor Subtype Selectivity

A Series of 6- and 7-Piperazinyl- and -Piperidinylmethylbenzoxazinones with Dopamine D4 Antagonist Activity: Discovery of a Potential Atypical Antipsychotic Agent

Discovery of PF-00217830: Aryl piperazine napthyridinones as D 2 partial agonists for schizophrenia and bipolar disorder

Aryl 1-But-3-ynyl-4-phenyl-1,2,3,6-tetrahydropyridines as Potential Antipsychotic Agents: Synthesis and Structure−Activity Relationships

Design and Structure-Activity Relationships of C-Terminal Cyclic Neurotensin Fragment Analogs

3-Arylimino-2-indolones Are Potent and Selective Galanin GAL3 Receptor Antagonists

Substituted [(4-Phenylpiperazinyl)- methyl]benzamides: Selective Dopamine D4 Agonists

Discovery of PF-00217830: Aryl piperazine napthyridinones as D sub(2 partial agonists for schizophrenia and bipolar disorder)

Pyrazolo[1,5-a]pyrimidine CRF-1 receptor antagonists

Substituted [(4-Phenylpiperazinyl)- methyl]benzamides: Selective Dopamine D 4 Agonists

3-Arylimino-2-indolones Are Potent and Selective Galanin GAL 3 Receptor Antagonists

3-arylimino-2-indolones are potent and selective galanin GAL3receptor antagonists

Affinity for Dopamine D 2 , D 3 , and D 4 Receptors of 2-Aminotetralins. Relevance of D 2 Agonist Binding for Determination of Receptor Subtype Selectivity

GBR12909 antagonizes the ability of cocaine to elevate extracellular levels of dopamine

The discovery of PD 89211 and related compounds: Selective dopamine D4 receptor antagonists

Aminopyrimidines with High Affinity for Both Serotonin and Dopamine Receptors

Identification of a GBR12935 homolog, LR1111, which is over 4,000-fold selective for the dopamine transporter, relative to serotonin and norepinephrine transporters

Serotonin modulation of pain responsiveness in the aged rat

Characterization of binding of [ 3H]PD 128907, A selective Dopamine D 3 receptor agonist ligand, to CHO-K1 cells

Characterization of binding of [3H]PD 128907, a selective dopamine D3 receptor agonist ligand, to CHO-K1 cells

Novel cyclohexyl amides as potent and selective D 3 dopamine receptor ligands

Novel cyclohexyl amides as potent and selective D3 dopamine receptor ligands

Behavioral and neurochemical changes in the dopaminergic system after repeated cocaine administration

Pharmacological characterization of PD 152255, a novel dimeric benzimidazole dopamine D3 antagonist

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