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Ancient drug curcumin impedes 26S proteasome activity by direct inhibition of dual-specificity tyrosine-regulated kinase 2

Proceedings of the National Academy of Sciences - PNAS, 2018-08, Vol.115 (32), p.8155-8160

2018

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Myeloid-derived suppressor cells inhibit T cell activation through nitrating LCK in mouse cancers

Proceedings of the National Academy of Sciences - PNAS, 2018-10, Vol.115 (40), p.10094-10099

2018

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Regulation of Protein Kinase Cβ I by Two Protein-Tyrosine Kinases, Btk and Syk

Proceedings of the National Academy of Sciences - PNAS, 2000-06, Vol.97 (13), p.7423-7428

2000

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Structural insight into selectivity and resistance profiles of ROS1 tyrosine kinase inhibitors

Proceedings of the National Academy of Sciences - PNAS, 2015-09, Vol.112 (39), p.E5381-E5390

2015

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coreceptor CD4 is expressed in distinct nanoclusters and does not colocalize with T-cell receptor and active protein tyrosine kinase p56lck

Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (13), p.E1604-E1613

2015

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Lipid-targeting pleckstrin homology domain turns its autoinhibitory face toward the TEC kinases

Proceedings of the National Academy of Sciences - PNAS, 2019-10, Vol.116 (43), p.21539-21544

2019

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MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation

Proceedings of the National Academy of Sciences - PNAS, 2016-06, Vol.113 (23), p.6526-6531

2016

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Cytokine receptor signaling is required for the survival of ALK− anaplastic large cell lymphoma, even in the presence of JAK1/STAT3 mutations

Proceedings of the National Academy of Sciences - PNAS, 2017-04, Vol.114 (15), p.3975-3980

2017

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Structural basis for the recognition of the bacterial tyrosine kinase Wzc by its cognate tyrosine phosphatase Wzb

Proceedings of the National Academy of Sciences - PNAS, 2022-06, Vol.119 (26), p.e2201800119-e2201800119

2022

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Identification of a biologically active fragment of ALK and LTK-Ligand 2 (augmentor-α)

Proceedings of the National Academy of Sciences - PNAS, 2018-08, Vol.115 (33), p.8340-8345

2018

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Phosphorylation-induced conformational dynamics in an intrinsically disordered protein and potential role in phenotypic heterogeneity

Proceedings of the National Academy of Sciences - PNAS, 2017-03, Vol.114 (13), p.E2644-E2653

2017

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Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1)

Proceedings of the National Academy of Sciences - PNAS, 2008-12, Vol.105 (52), p.20852-20857

2008

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Molecular basis for autoinhibition of RIAM regulated by FAK in integrin activation

Proceedings of the National Academy of Sciences - PNAS, 2019-02, Vol.116 (9), p.3524-3529

2019

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Selective Inhibition of the Platelet-Derived Growth Factor Signal Transduction Pathway by a Protein-Tyrosine Kinase Inhibitor of the 2- Phenylaminopyrimidine Class

Proceedings of the National Academy of Sciences - PNAS, 1995-03, Vol.92 (7), p.2558-2562

1995

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Targeting Axl favors an antitumorigenic microenvironment that enhances immunotherapy responses by decreasing Hif-1α levels

Proceedings of the National Academy of Sciences - PNAS, 2021-07, Vol.118 (29), p.1

2021

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Phosphatidylinositol 4,5-bisphosphate triggers activation of focal adhesion kinase by inducing clustering and conformational changes

Proceedings of the National Academy of Sciences - PNAS, 2014-08, Vol.111 (31), p.E3177-E3186

2014

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FcεRI-Mediated Tyrosine Phosphorylation and Activation of the 72-kDa Protein-Tyrosine Kinase, PTK72, in RBL-2H3 Rat Tumor Mast Cells

Proceedings of the National Academy of Sciences - PNAS, 1992-10, Vol.89 (19), p.9107-9111

1992

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MicroRNA Profiling Reveals Distinct Signatures in B Cell Chronic Lymphocytic Leukemias

Proceedings of the National Academy of Sciences - PNAS, 2004-08, Vol.101 (32), p.11755-11760

2004

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12/15-lipoxygenase–derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases

Proceedings of the National Academy of Sciences - PNAS, 2010-09, Vol.107 (36), p.15774-15779

2010

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Signal Transduction in Macrophages by Glycosylphosphatidylinositols of Plasmodium, Trypanosoma, and Leishmania: Activation of Protein Tyrosine Kinases and Protein Kinase C by Inositolglycan and Diacylglycerol Moieties

Proceedings of the National Academy of Sciences - PNAS, 1997-04, Vol.94 (8), p.4022-4027

1997

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Tyrosine Phosphatase CD45 is Required for T-Cell Antigen Receptor and CD2- Mediated Activation of a Protein Tyrosine Kinase and Interleukin 2 Production

Proceedings of the National Academy of Sciences - PNAS, 1991-03, Vol.88 (6), p.2037-2041

1991

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Identification of differential and functionally active miRNAs in both anaplastic lymphoma kinase (ALK)⁺ and ALK⁻ anaplastic large-cell lymphoma

Proceedings of the National Academy of Sciences - PNAS, 2010-09, Vol.107 (37), p.16228-16233

2010

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TCR signaling via Tec kinase ITK and interferon regulatory factor 4 (IRF4) regulates CD8⁺ T-cell differentiation

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (41), p.E2794-E2802

2012

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Evolution of ibrutinib resistance in chronic lymphocytic leukemia (CLL)

Proceedings of the National Academy of Sciences - PNAS, 2014-09, Vol.111 (38), p.13906-13911

2014

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Molecular Structure of a Protein-Tyrosine/Threonine Kinase Activating p42 Mitogen-Activated Protein (MAP) Kinase: MAP Kinase Kinase

Proceedings of the National Academy of Sciences - PNAS, 1993-01, Vol.90 (1), p.173-177

1993

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Ancient drug curcumin impedes 26S proteasome activity by direct inhibition of dual-specificity tyrosine-regulated kinase 2

Myeloid-derived suppressor cells inhibit T cell activation through nitrating LCK in mouse cancers

Regulation of Protein Kinase Cβ I by Two Protein-Tyrosine Kinases, Btk and Syk

Structural insight into selectivity and resistance profiles of ROS1 tyrosine kinase inhibitors

coreceptor CD4 is expressed in distinct nanoclusters and does not colocalize with T-cell receptor and active protein tyrosine kinase p56lck

Lipid-targeting pleckstrin homology domain turns its autoinhibitory face toward the TEC kinases

MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation

Cytokine receptor signaling is required for the survival of ALK− anaplastic large cell lymphoma, even in the presence of JAK1/STAT3 mutations

Structural basis for the recognition of the bacterial tyrosine kinase Wzc by its cognate tyrosine phosphatase Wzb

Identification of a biologically active fragment of ALK and LTK-Ligand 2 (augmentor-α)

Phosphorylation-induced conformational dynamics in an intrinsically disordered protein and potential role in phenotypic heterogeneity

Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1)

Molecular basis for autoinhibition of RIAM regulated by FAK in integrin activation

Selective Inhibition of the Platelet-Derived Growth Factor Signal Transduction Pathway by a Protein-Tyrosine Kinase Inhibitor of the 2- Phenylaminopyrimidine Class

Targeting Axl favors an antitumorigenic microenvironment that enhances immunotherapy responses by decreasing Hif-1α levels

Phosphatidylinositol 4,5-bisphosphate triggers activation of focal adhesion kinase by inducing clustering and conformational changes

FcεRI-Mediated Tyrosine Phosphorylation and Activation of the 72-kDa Protein-Tyrosine Kinase, PTK72, in RBL-2H3 Rat Tumor Mast Cells

MicroRNA Profiling Reveals Distinct Signatures in B Cell Chronic Lymphocytic Leukemias

12/15-lipoxygenase–derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases

Signal Transduction in Macrophages by Glycosylphosphatidylinositols of Plasmodium, Trypanosoma, and Leishmania: Activation of Protein Tyrosine Kinases and Protein Kinase C by Inositolglycan and Diacylglycerol Moieties

Tyrosine Phosphatase CD45 is Required for T-Cell Antigen Receptor and CD2- Mediated Activation of a Protein Tyrosine Kinase and Interleukin 2 Production

Identification of differential and functionally active miRNAs in both anaplastic lymphoma kinase (ALK)⁺ and ALK⁻ anaplastic large-cell lymphoma

TCR signaling via Tec kinase ITK and interferon regulatory factor 4 (IRF4) regulates CD8⁺ T-cell differentiation

Evolution of ibrutinib resistance in chronic lymphocytic leukemia (CLL)

Molecular Structure of a Protein-Tyrosine/Threonine Kinase Activating p42 Mitogen-Activated Protein (MAP) Kinase: MAP Kinase Kinase

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