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Mechanism and molecular basis for the sodium channel subtype specificity of µ‐conopeptide CnIIIC

British journal of pharmacology, 2012-10, Vol.167 (3), p.576-586

2012

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Comprehensive engineering of the tarantula venom peptide huwentoxin-IV to inhibit the human voltage-gated sodium channel hNa v 1.7

The Journal of biological chemistry, 2020-01, Vol.295 (5), p.1315-1327

2020

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The opioid methadone induces a local anaesthetic-like inhibition of the cardiac Na⁺ channel, Na(v)1.5

British journal of pharmacology, 2014-01, Vol.171 (2), p.427

2014

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International Union of Basic and Clinical Pharmacology. XCI. structure, function, and pharmacology of acid-sensing ion channels and the epithelial Na+ channel

Pharmacological reviews, 2015-01, Vol.67 (1), p.1-35

2015

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The Concise Guide to PHARMACOLOGY 2015/16: Voltage‐gated ion channels

British journal of pharmacology, 2015-12, Vol.172 (24), p.5904-5941

2015

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Gain-of-function mutations in the MEC-4 DEG/ENaC sensory mechanotransduction channel alter gating and drug blockade

The Journal of general physiology, 2007-02, Vol.129 (2), p.161-173

2007

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Inhibition of Protease-Epithelial Sodium Channel Signaling Improves Mucociliary Function in Cystic Fibrosis Airways

American journal of respiratory and critical care medicine, 2016-09, Vol.194 (6), p.701-710

2016

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Anticancer drug oxaliplatin induces acute cooling-aggravated neuropathy via sodium channel subtype Na(V)1.6-resurgent and persistent current

Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (17), p.6704

2012

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International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels

Pharmacological reviews, 2005-12, Vol.57 (4), p.397-409

2005

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TRPV4 channels mediate the infrared laser-evoked response in sensory neurons

Journal of neurophysiology, 2012-06, Vol.107 (12), p.3227-3234

2012

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Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET

Proceedings of the National Academy of Sciences - PNAS, 2017-03, Vol.114 (10), p.E1857-E1865

2017

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Subicular pyramidal neurons gate drug resistance in temporal lobe epilepsy

Annals of neurology, 2019-10, Vol.86 (4), p.626-640

2019

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Subtype‐selective targeting of voltage‐gated sodium channels

British journal of pharmacology, 2009-11, Vol.158 (6), p.1413-1425

2009

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Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics

The Journal of general physiology, 2013-01, Vol.141 (1), p.61-72

2013

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Scorpion beta-toxins and voltage-gated sodium channels: interactions and effects

Frontiers in bioscience, 2013-01, Vol.18 (2), p.572

2013

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Modulation of a voltage-gated Na+channel by sevoflurane involves multiple sites and distinct mechanisms

Proceedings of the National Academy of Sciences - PNAS, 2014-05, Vol.111 (18), p.6726-6731

2014

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Inhibition of voltage‐gated Na+ currents in sensory neurones by the sea anemone toxin APETx2

British journal of pharmacology, 2012-04, Vol.165 (7), p.2167-2177

2012

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Engineering Highly Potent and Selective Microproteins against Nav1.7 Sodium Channel for Treatment of Pain

The Journal of biological chemistry, 2016-07, Vol.291 (27), p.13974-13986

2016

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Ion channels as drug targets: the next GPCRs

The Journal of general physiology, 2008-05, Vol.131 (5), p.399-405

2008

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Regulation of sodium channel function by bilayer elasticity: the importance of hydrophobic coupling. Effects of Micelle-forming amphiphiles and cholesterol

The Journal of general physiology, 2004-05, Vol.123 (5), p.599-621

2004

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Differential effects on fast and slow spindle activity, and the sleep slow oscillation in humans with carbamazepine and flunarizine to antagonize voltage-dependent Na+ and Ca2+ channel activity

Sleep (New York, N.Y.), 2013-06, Vol.36 (6), p.905-911

2013

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Naja atra venom peptide reduces pain by selectively blocking the voltage-gated sodium channel Nav1.8

The Journal of biological chemistry, 2019-05, Vol.294 (18), p.7324-7334

2019

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An increase in persistent sodium current contributes to intrinsic neuronal bursting after status epilepticus

Journal of neurophysiology, 2011-01, Vol.105 (1), p.117-129

2011

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Hypoxia-induced inhibition of epithelial Na(+) channels in the lung. Role of Nedd4-2 and the ubiquitin-proteasome pathway

American journal of respiratory cell and molecular biology, 2014-03, Vol.50 (3), p.526-537

2014

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Sodium sensitivity of K Na channels in mouse CA1 neurons

Journal of neurophysiology, 2021-05, Vol.125 (5), p.1690-1697

2021

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Mechanism and molecular basis for the sodium channel subtype specificity of µ‐conopeptide CnIIIC

Comprehensive engineering of the tarantula venom peptide huwentoxin-IV to inhibit the human voltage-gated sodium channel hNa v 1.7

The opioid methadone induces a local anaesthetic-like inhibition of the cardiac Na⁺ channel, Na(v)1.5

International Union of Basic and Clinical Pharmacology. XCI. structure, function, and pharmacology of acid-sensing ion channels and the epithelial Na+ channel

The Concise Guide to PHARMACOLOGY 2015/16: Voltage‐gated ion channels

Gain-of-function mutations in the MEC-4 DEG/ENaC sensory mechanotransduction channel alter gating and drug blockade

Inhibition of Protease-Epithelial Sodium Channel Signaling Improves Mucociliary Function in Cystic Fibrosis Airways

Anticancer drug oxaliplatin induces acute cooling-aggravated neuropathy via sodium channel subtype Na(V)1.6-resurgent and persistent current

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels

TRPV4 channels mediate the infrared laser-evoked response in sensory neurons

Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET

Subicular pyramidal neurons gate drug resistance in temporal lobe epilepsy

Subtype‐selective targeting of voltage‐gated sodium channels

Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics

Scorpion beta-toxins and voltage-gated sodium channels: interactions and effects

Modulation of a voltage-gated Na+channel by sevoflurane involves multiple sites and distinct mechanisms

Inhibition of voltage‐gated Na+ currents in sensory neurones by the sea anemone toxin APETx2

Engineering Highly Potent and Selective Microproteins against Nav1.7 Sodium Channel for Treatment of Pain

Ion channels as drug targets: the next GPCRs

Regulation of sodium channel function by bilayer elasticity: the importance of hydrophobic coupling. Effects of Micelle-forming amphiphiles and cholesterol

Differential effects on fast and slow spindle activity, and the sleep slow oscillation in humans with carbamazepine and flunarizine to antagonize voltage-dependent Na+ and Ca2+ channel activity

Naja atra venom peptide reduces pain by selectively blocking the voltage-gated sodium channel Nav1.8

An increase in persistent sodium current contributes to intrinsic neuronal bursting after status epilepticus

Hypoxia-induced inhibition of epithelial Na(+) channels in the lung. Role of Nedd4-2 and the ubiquitin-proteasome pathway

Sodium sensitivity of K Na channels in mouse CA1 neurons

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