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Illustration of SSMD, z score, SSMD, z score, and t statistic for hit selection in RNAi high-throughput screens

Journal of biomolecular screening, 2011-08, Vol.16 (7), p.775-785

Zhang, Xiaohua Douglas

2011

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The use of real-time cell analyzer technology in drug discovery: defining optimal cell culture conditions and assay reproducibility with different adherent cellular models

Journal of biomolecular screening, 2011-07, Vol.16 (6), p.575-587

2011

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Permeation of Antibiotics through Escherichia coli OmpF and OmpC Porins: Screening for Influx on a Single-Molecule Level

Journal of biomolecular screening, 2010-03, Vol.15 (3), p.302-307

2010

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Screening for Inhibitors of Low-Affinity Epigenetic Peptide-Protein Interactions: An AlphaScreen™-Based Assay for Antagonists of Methyl-Lysine Binding Proteins

Journal of biomolecular screening, 2010-01, Vol.15 (1), p.62-71

2010

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Open innovation for phenotypic drug discovery: The PD2 assay panel

Journal of biomolecular screening, 2011-07, Vol.16 (6), p.588-602

2011

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A fluorescence-based alkaline phosphatase-coupled polymerase assay for identification of inhibitors of dengue virus RNA-dependent RNA polymerase

Journal of biomolecular screening, 2011-02, Vol.16 (2), p.201-210

2011

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Plate-Based Diversity Selection Based on Empirical HTS Data to Enhance the Number of Hits and Their Chemical Diversity

Journal of biomolecular screening, 2009-07, Vol.14 (6), p.690-699

2009

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Alantolactone inhibits cell proliferation by interrupting the interaction between Cripto-1 and activin receptor type II A in activin signaling pathway

Journal of biomolecular screening, 2011-06, Vol.16 (5), p.525-535

2011

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Integration of Multiple Readouts into the Z′ Factor for Assay Quality Assessment

Journal of biomolecular screening, 2010-01, Vol.15 (1), p.95-101

2010

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Understanding the effect of different assay formats on agonist parameters: a study using the µ-opioid receptor

Journal of biomolecular screening, 2011-08, Vol.16 (7), p.706-716

2011

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The quenching effect of flavonoids on 4-methylumbelliferone, a potential pitfall in fluorimetric neuraminidase inhibition assays

Journal of biomolecular screening, 2011-08, Vol.16 (7), p.755-764

2011

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Electrical impedance as a novel biomarker of myotube atrophy and hypertrophy

Journal of biomolecular screening, 2011-07, Vol.16 (6), p.565-574

2011

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Identification of a potential biomarker for FABP4 inhibition: the power of lipidomics in preclinical drug testing

Journal of biomolecular screening, 2011-06, Vol.16 (5), p.467-475

2011

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Enhancing recombinant protein quality and yield by protein stability profiling

Journal of biomolecular screening, 2007-04, Vol.12 (3), p.418-428

2007

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Dequalinium, a New Inhibitor of Mycobacterium tuberculosis Mycothiol Ligase Identified by High-Throughput Screening

Journal of biomolecular screening, 2009-07, Vol.14 (6), p.643-652

2009

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JBS: advancing the science of drug discovery for 20 years

Journal of biomolecular screening, 2015-01, Vol.20 (1), p.1-2

Campbell, Robert M

2015

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PDMS Compound Adsorption in Context

Journal of biomolecular screening, 2009-02, Vol.14 (2), p.194-202

2009

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Development and application of a cellular, gain-of-signal, bioluminescent reporter screen for inhibitors of type II secretion in Pseudomonas aeruginosa and Burkholderia pseudomallei

Journal of biomolecular screening, 2011-08, Vol.16 (7), p.694-705

2011

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Multidrug Resistance Reversal Agent, NSC77037, Identified with a Cell-Based Screening Assay

Journal of biomolecular screening, 2010-03, Vol.15 (3), p.287-296

2010

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DetecTiff©: A Novel Image Analysis Routine for High-Content Screening Microscopy

Journal of biomolecular screening, 2009-09, Vol.14 (8), p.944-955

2009

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Microarray analysis of gene expression profiles of rat small intestine in response to heat stress

Journal of biomolecular screening, 2011-07, Vol.16 (6), p.655-667

2011

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Multiplexed reporter gene assays: monitoring the cell viability and the compound kinetics on luciferase activity

Journal of biomolecular screening, 2011-08, Vol.16 (7), p.786-793

2011

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Identification and Preliminary Characterization of Novel Small Molecules That Inhibit Growth of Human Lung Adenocarcinoma Cells

Journal of biomolecular screening, 2009-12, Vol.14 (10), p.1176-1184

2009

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Atom- and Bond-Based 2D TOMOCOMD-CARDD Approach and Ligand-Based Virtual Screening for the Drug Discovery of New Tyrosinase Inhibitors

Journal of biomolecular screening, 2008-12, Vol.13 (10), p.1014-1024

2008

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A quantitative high-throughput screen identifies novel inhibitors of the interaction of thyroid receptor beta with a peptide of steroid receptor coactivator 2

Journal of biomolecular screening, 2011-07, Vol.16 (6), p.618-627

2011

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Illustration of SSMD, z score, SSMD, z score, and t statistic for hit selection in RNAi high-throughput screens

The use of real-time cell analyzer technology in drug discovery: defining optimal cell culture conditions and assay reproducibility with different adherent cellular models

Permeation of Antibiotics through Escherichia coli OmpF and OmpC Porins: Screening for Influx on a Single-Molecule Level

Screening for Inhibitors of Low-Affinity Epigenetic Peptide-Protein Interactions: An AlphaScreen™-Based Assay for Antagonists of Methyl-Lysine Binding Proteins

Open innovation for phenotypic drug discovery: The PD2 assay panel

A fluorescence-based alkaline phosphatase-coupled polymerase assay for identification of inhibitors of dengue virus RNA-dependent RNA polymerase

Plate-Based Diversity Selection Based on Empirical HTS Data to Enhance the Number of Hits and Their Chemical Diversity

Alantolactone inhibits cell proliferation by interrupting the interaction between Cripto-1 and activin receptor type II A in activin signaling pathway

Integration of Multiple Readouts into the Z′ Factor for Assay Quality Assessment

Understanding the effect of different assay formats on agonist parameters: a study using the µ-opioid receptor

The quenching effect of flavonoids on 4-methylumbelliferone, a potential pitfall in fluorimetric neuraminidase inhibition assays

Electrical impedance as a novel biomarker of myotube atrophy and hypertrophy

Identification of a potential biomarker for FABP4 inhibition: the power of lipidomics in preclinical drug testing

Enhancing recombinant protein quality and yield by protein stability profiling

Dequalinium, a New Inhibitor of Mycobacterium tuberculosis Mycothiol Ligase Identified by High-Throughput Screening

JBS: advancing the science of drug discovery for 20 years

PDMS Compound Adsorption in Context

Development and application of a cellular, gain-of-signal, bioluminescent reporter screen for inhibitors of type II secretion in Pseudomonas aeruginosa and Burkholderia pseudomallei

Multidrug Resistance Reversal Agent, NSC77037, Identified with a Cell-Based Screening Assay

DetecTiff©: A Novel Image Analysis Routine for High-Content Screening Microscopy

Microarray analysis of gene expression profiles of rat small intestine in response to heat stress

Multiplexed reporter gene assays: monitoring the cell viability and the compound kinetics on luciferase activity

Identification and Preliminary Characterization of Novel Small Molecules That Inhibit Growth of Human Lung Adenocarcinoma Cells

Atom- and Bond-Based 2D TOMOCOMD-CARDD Approach and Ligand-Based Virtual Screening for the Drug Discovery of New Tyrosinase Inhibitors

A quantitative high-throughput screen identifies novel inhibitors of the interaction of thyroid receptor beta with a peptide of steroid receptor coactivator 2

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