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Hemagglutinin activating host cell proteases provide promising drug targets for the treatment of influenza A and B virus infections

Vaccine, 2012-12, Vol.30 (51), p.7374-7380

2012

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Novel proteolytic activation of Ebolavirus glycoprotein GP by TMPRSS2 and cathepsin L at an uncharted position can compensate for furin cleavage

Virus research, 2024-09, Vol.347, p.199430, Article 199430

2024

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Peptidomimetic furin inhibitor MI-701 in combination with oseltamivir and ribavirin efficiently blocks propagation of highly pathogenic avian influenza viruses and delays high level oseltamivir resistance in MDCK cells

Antiviral research, 2015-08, Vol.120, p.89-100

2015

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Influenza virus activating host proteases: Identification, localization and inhibitors as potential therapeutics

European journal of cell biology, 2015-07, Vol.94 (7-9), p.375-383

2015

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Development of substrate analogue inhibitors for the human airway trypsin-like protease HAT

Bioorganic & medicinal chemistry letters, 2011-08, Vol.21 (16), p.4860-4864

2011

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SARS-CoV-2 variants B.1.351 and P.1 escape from neutralizing antibodies

Cell, 2021-04, Vol.184 (9), p.2384-2393.e12

2021

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A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation

Cell, 2015-02, Vol.160 (4), p.631-643

2015

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SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

Cell, 2020-05, Vol.181 (5), p.1016-1035.e19

2020

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Receptor-binding properties of influenza viruses isolated from gulls

Virology (New York, N.Y.), 2018-09, Vol.522, p.37-45

2018

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Momordica charantia extract, a herbal remedy for type 2 diabetes, contains a specific 11β-hydroxysteroid dehydrogenase type 1 inhibitor

The Journal of steroid biochemistry and molecular biology, 2012, Vol.128 (1), p.51-55

2012

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Partial purification and characterization of a new human membrane-bound carbonyl reductase playing a role in the deactivation of the anticancer drug oracin

Toxicology (Amsterdam), 2009-10, Vol.264 (1), p.52-60

2009

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Human 11β-hydroxysteroid dehydrogenase 1/carbonyl reductase: recombinant expression in the yeast Pichia pastoris and Escherichia coli

Toxicology (Amsterdam), 2000-04, Vol.144 (1), p.113-120

2000

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11β-Hydroxysteroid dehydrogenase type 1: tissue-specific expression and reductive metabolism of some anti-insect agent azole analogues of metyrapone

Chemico-biological interactions, 2003-02, Vol.143, p.449-457

2003

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Human 11β-hydroxysteroid dehydrogenase 1/carbonyl reductase: additional domains for membrane attachment?

Chemico-biological interactions, 2001-01, Vol.130, p.749-759

2001

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A novel membrane associated carbonyl reducing enzyme is present in smooth endoplasmic reticulum of mouse liver

Biochemical and biophysical research communications, 1992-12, Vol.189 (2), p.736-742

1992

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In vitro characterization of the furin inhibitor MI-1851: Albumin binding, interaction with cytochrome P450 enzymes and cytotoxicity

Biomedicine & pharmacotherapy, 2022-07, Vol.151, p.113124-113124, Article 113124

2022

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Mimicking the passage of avian influenza viruses through the gastrointestinal tract of chickens

Veterinary microbiology, 2019-12, Vol.239, p.108462-108462, Article 108462

2019

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In vitro interaction of potential antiviral TMPRSS2 inhibitors with human serum albumin and cytochrome P 450 isoenzymes

Biomedicine & pharmacotherapy, 2022-02, Vol.146, p.112513-112513, Article 112513

2022

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Cathepsin L-selective inhibitors: A potentially promising treatment for COVID-19 patients

Pharmacology & therapeutics (Oxford), 2020-09, Vol.213, p.107587-107587, Article 107587

2020

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TMPRSS2-specific antisense oligonucleotides inhibit host cell entry of emerging viruses

Virology (New York, N.Y.), 2024-12, Vol.600, p.110218, Article 110218

2024

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Anti-influenza activity of CPAVM1 protease secreted by Bacillus subtilis LjM2

Antiviral research, 2024-08, Vol.228, p.105919, Article 105919

2024

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TMPRSS2: A potential target for treatment of influenza virus and coronavirus infections

Biochimie, 2017-11, Vol.142, p.1-10

2017

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Impact of inhaled pollutants on response to viral infection in controlled exposures

Journal of allergy and clinical immunology, 2021-12, Vol.148 (6), p.1420-1429

2021

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BpAFP, a Broussonetia papyrifera latex chitinase, exhibits a dual role in resisting to both Verticillium wilt disease and lepidopterous pests, Plutella xylostella and Prodenia litura

Plant science (Limerick), 2024-09, Vol.346, p.112161, Article 112161

2024

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Identification of key hemagglutinin residues responsible for cleavage, acid stability, and virulence of fifth-wave highly pathogenic avian influenza A(H7N9) viruses

Virology (New York, N.Y.), 2019-09, Vol.535, p.232-240

2019

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Hemagglutinin activating host cell proteases provide promising drug targets for the treatment of influenza A and B virus infections

Novel proteolytic activation of Ebolavirus glycoprotein GP by TMPRSS2 and cathepsin L at an uncharted position can compensate for furin cleavage

Peptidomimetic furin inhibitor MI-701 in combination with oseltamivir and ribavirin efficiently blocks propagation of highly pathogenic avian influenza viruses and delays high level oseltamivir resistance in MDCK cells

Influenza virus activating host proteases: Identification, localization and inhibitors as potential therapeutics

Development of substrate analogue inhibitors for the human airway trypsin-like protease HAT

SARS-CoV-2 variants B.1.351 and P.1 escape from neutralizing antibodies

A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation

SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

Receptor-binding properties of influenza viruses isolated from gulls

Momordica charantia extract, a herbal remedy for type 2 diabetes, contains a specific 11β-hydroxysteroid dehydrogenase type 1 inhibitor

Partial purification and characterization of a new human membrane-bound carbonyl reductase playing a role in the deactivation of the anticancer drug oracin

Human 11β-hydroxysteroid dehydrogenase 1/carbonyl reductase: recombinant expression in the yeast Pichia pastoris and Escherichia coli

11β-Hydroxysteroid dehydrogenase type 1: tissue-specific expression and reductive metabolism of some anti-insect agent azole analogues of metyrapone

Human 11β-hydroxysteroid dehydrogenase 1/carbonyl reductase: additional domains for membrane attachment?

A novel membrane associated carbonyl reducing enzyme is present in smooth endoplasmic reticulum of mouse liver

In vitro characterization of the furin inhibitor MI-1851: Albumin binding, interaction with cytochrome P450 enzymes and cytotoxicity

Mimicking the passage of avian influenza viruses through the gastrointestinal tract of chickens

In vitro interaction of potential antiviral TMPRSS2 inhibitors with human serum albumin and cytochrome P 450 isoenzymes

Cathepsin L-selective inhibitors: A potentially promising treatment for COVID-19 patients

TMPRSS2-specific antisense oligonucleotides inhibit host cell entry of emerging viruses

Anti-influenza activity of CPAVM1 protease secreted by Bacillus subtilis LjM2

TMPRSS2: A potential target for treatment of influenza virus and coronavirus infections

Impact of inhaled pollutants on response to viral infection in controlled exposures

BpAFP, a Broussonetia papyrifera latex chitinase, exhibits a dual role in resisting to both Verticillium wilt disease and lepidopterous pests, Plutella xylostella and Prodenia litura

Identification of key hemagglutinin residues responsible for cleavage, acid stability, and virulence of fifth-wave highly pathogenic avian influenza A(H7N9) viruses

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