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Hemagglutinin activating host cell proteases provide promising drug targets for the treatment of influenza A and B virus infections

Vaccine, 2012-12, Vol.30 (51), p.7374-7380

2012

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Peptidomimetic furin inhibitor MI-701 in combination with oseltamivir and ribavirin efficiently blocks propagation of highly pathogenic avian influenza viruses and delays high level oseltamivir resistance in MDCK cells

Antiviral research, 2015-08, Vol.120, p.89-100

2015

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Influenza virus activating host proteases: Identification, localization and inhibitors as potential therapeutics

European journal of cell biology, 2015-07, Vol.94 (7-9), p.375-383

2015

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Development of substrate analogue inhibitors for the human airway trypsin-like protease HAT

Bioorganic & medicinal chemistry letters, 2011-08, Vol.21 (16), p.4860-4864

2011

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SARS-CoV-2 variants B.1.351 and P.1 escape from neutralizing antibodies

Cell, 2021-04, Vol.184 (9), p.2384-2393.e12

2021

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A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation

Cell, 2015-02, Vol.160 (4), p.631-643

2015

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SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

Cell, 2020-05, Vol.181 (5), p.1016-1035.e19

2020

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Receptor-binding properties of influenza viruses isolated from gulls

Virology (New York, N.Y.), 2018-09, Vol.522, p.37-45

2018

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Adaptive mutation PB2 D701N promotes nuclear import of influenza vRNPs in mammalian cells

European journal of cell biology, 2015-07, Vol.94 (7-9), p.368-374

2015

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Momordica charantia extract, a herbal remedy for type 2 diabetes, contains a specific 11β-hydroxysteroid dehydrogenase type 1 inhibitor

The Journal of steroid biochemistry and molecular biology, 2012, Vol.128 (1), p.51-55

2012

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11β-Hydroxysteroid dehydrogenase type 1: tissue-specific expression and reductive metabolism of some anti-insect agent azole analogues of metyrapone

Chemico-biological interactions, 2003-02, Vol.143, p.449-457

2003

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Human 11β-hydroxysteroid dehydrogenase 1/carbonyl reductase: recombinant expression in the yeast Pichia pastoris and Escherichia coli

Toxicology (Amsterdam), 2000-04, Vol.144 (1), p.113-120

2000

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Human 11β-hydroxysteroid dehydrogenase 1/carbonyl reductase: additional domains for membrane attachment?

Chemico-biological interactions, 2001-01, Vol.130, p.749-759

2001

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A novel membrane associated carbonyl reducing enzyme is present in smooth endoplasmic reticulum of mouse liver

Biochemical and biophysical research communications, 1992-12, Vol.189 (2), p.736-742

1992

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In vitro characterization of the furin inhibitor MI-1851: Albumin binding, interaction with cytochrome P450 enzymes and cytotoxicity

Biomedicine & pharmacotherapy, 2022-07, Vol.151, p.113124-113124, Article 113124

2022

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In vitro interaction of potential antiviral TMPRSS2 inhibitors with human serum albumin and cytochrome P 450 isoenzymes

Biomedicine & pharmacotherapy, 2022-02, Vol.146, p.112513-112513, Article 112513

2022

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TMPRSS2: A potential target for treatment of influenza virus and coronavirus infections

Biochimie, 2017-11, Vol.142, p.1-10

2017

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Impact of inhaled pollutants on response to viral infection in controlled exposures

Journal of allergy and clinical immunology, 2021-12, Vol.148 (6), p.1420-1429

2021

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Modification of the hemagglutinin cleavage site allows indirect activation of avian influenza virus H9N2 by bacterial staphylokinase

Virology (New York, N.Y.), 2015-08, Vol.482, p.1-8

2015

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Use of natural cysteine protease inhibitors in limiting SARS-Co-2 fusion into human respiratory cells

Medical hypotheses, 2022-11, Vol.168, p.110965, Article 110965

2022

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Enzymatic evaluation of chromenone derivatives from Flemingia philippinensis as viral neuraminidase (H3N2) inhibitors

Journal of molecular structure, 2023-12, Vol.1293, p.136243, Article 136243

2023

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Mimicking the passage of avian influenza viruses through the gastrointestinal tract of chickens

Veterinary microbiology, 2019-12, Vol.239, p.108462-108462, Article 108462

2019

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Adaptive amino acid substitutions enhance the virulence of a reassortant H7N1 avian influenza virus isolated from wild waterfowl in mice

Virology (New York, N.Y.), 2015-02, Vol.476, p.233-239

2015

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Identification of key hemagglutinin residues responsible for cleavage, acid stability, and virulence of fifth-wave highly pathogenic avian influenza A(H7N9) viruses

Virology (New York, N.Y.), 2019-09, Vol.535, p.232-240

2019

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Screening S protein – ACE2 blockers from natural products: Strategies and advances in the discovery of potential inhibitors of COVID-19

European journal of medicinal chemistry, 2021-12, Vol.226, p.113857-113857, Article 113857

2021

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Hemagglutinin activating host cell proteases provide promising drug targets for the treatment of influenza A and B virus infections

Peptidomimetic furin inhibitor MI-701 in combination with oseltamivir and ribavirin efficiently blocks propagation of highly pathogenic avian influenza viruses and delays high level oseltamivir resistance in MDCK cells

Influenza virus activating host proteases: Identification, localization and inhibitors as potential therapeutics

Development of substrate analogue inhibitors for the human airway trypsin-like protease HAT

SARS-CoV-2 variants B.1.351 and P.1 escape from neutralizing antibodies

A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation

SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

Receptor-binding properties of influenza viruses isolated from gulls

Adaptive mutation PB2 D701N promotes nuclear import of influenza vRNPs in mammalian cells

Momordica charantia extract, a herbal remedy for type 2 diabetes, contains a specific 11β-hydroxysteroid dehydrogenase type 1 inhibitor

11β-Hydroxysteroid dehydrogenase type 1: tissue-specific expression and reductive metabolism of some anti-insect agent azole analogues of metyrapone

Human 11β-hydroxysteroid dehydrogenase 1/carbonyl reductase: recombinant expression in the yeast Pichia pastoris and Escherichia coli

Human 11β-hydroxysteroid dehydrogenase 1/carbonyl reductase: additional domains for membrane attachment?

A novel membrane associated carbonyl reducing enzyme is present in smooth endoplasmic reticulum of mouse liver

In vitro characterization of the furin inhibitor MI-1851: Albumin binding, interaction with cytochrome P450 enzymes and cytotoxicity

In vitro interaction of potential antiviral TMPRSS2 inhibitors with human serum albumin and cytochrome P 450 isoenzymes

TMPRSS2: A potential target for treatment of influenza virus and coronavirus infections

Impact of inhaled pollutants on response to viral infection in controlled exposures

Modification of the hemagglutinin cleavage site allows indirect activation of avian influenza virus H9N2 by bacterial staphylokinase

Use of natural cysteine protease inhibitors in limiting SARS-Co-2 fusion into human respiratory cells

Enzymatic evaluation of chromenone derivatives from Flemingia philippinensis as viral neuraminidase (H3N2) inhibitors

Mimicking the passage of avian influenza viruses through the gastrointestinal tract of chickens

Adaptive amino acid substitutions enhance the virulence of a reassortant H7N1 avian influenza virus isolated from wild waterfowl in mice

Identification of key hemagglutinin residues responsible for cleavage, acid stability, and virulence of fifth-wave highly pathogenic avian influenza A(H7N9) viruses

Screening S protein – ACE2 blockers from natural products: Strategies and advances in the discovery of potential inhibitors of COVID-19

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