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The ERK MAP kinase-PEA3/ETV4-MMP-1 axis is operative in oesophageal adenocarcinoma

Molecular cancer, 2010-12, Vol.9 (1), p.313-313, Article 313

2010

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The ERK-ZEB1 pathway mediates epithelial-mesenchymal transition in pemetrexed resistant lung cancer cells with suppression by vinca alkaloids

Oncogene, 2017-01, Vol.36 (2), p.242-253

2017

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Lovastatin inhibits erythroleukemia progression through KLF2-mediated suppression of MAPK/ERK signaling

BMC cancer, 2023-04, Vol.23 (1), p.306-306, Article 306

2023

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Phosphorylation of cofilin-1 by ERK confers HDAC inhibitor resistance in hepatocellular carcinoma cells via decreased ROS-mediated mitochondria injury

Oncogene, 2017-04, Vol.36 (14), p.1978-1990

2017

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Dopaminergic tone regulates transient potassium current maximal conductance through a translational mechanism requiring D1Rs, cAMP/PKA, Erk and mTOR

BMC neuroscience, 2013-11, Vol.14 (1), p.143-143, Article 143

2013

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BCR ABL and IL-3 activate Rap1 to stimulate the B-Raf MEK Erk and Akt signaling pathways and to regulate proliferation, apoptosis, and adhesion

Oncogene, 2006-07, Vol.25 (31), p.4332-4340

2006

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Common alterations in gene expression and increased proliferation in recurrent acute myeloid leukemia

Oncogene, 2004-01, Vol.23 (4), p.894-904

2004

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Axl promotes cell invasion by inducing MMP-9 activity through activation of NF-κB and Brg-1

Oncogene, 2008-07, Vol.27 (29), p.4044-4055

2008

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The leukaemic oncoproteins Bcr-Abl and Tel-Abl (ETV6/Abl) have altered substrate preferences and activate similar intracellular signalling pathways

Oncogene, 2000-03, Vol.19 (13), p.1684-1690

2000

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Time-resolved relaxation and fragmentation of polycyclic aromatic hydrocarbons investigated in the ultrafast XUV-IR regime

Nature communications, 2021-10, Vol.12 (1), p.6107-6107, Article 6107

2021

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Reversal of cocaine―evoked synaptic potentiation resets drug―induced adaptive behaviour

Nature (London), 2012-01, Vol.481 (7379), p.71-75

2012

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Uncodified Workings and Unworkable Codes: Canadian Federalism and Public Policy

Comparative political studies, 2006-05, Vol.39 (4), p.441-462

Erk, Jan

2006

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Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP

Nature (London), 1999-09, Vol.401 (6749), p.173-177

1999

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Inhibition of glioblastoma dispersal by the MEK inhibitor PD0325901

BMC cancer, 2017-02, Vol.17 (1), p.121-121, Article 121

2017

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Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma

Nature genetics, 2012-02, Vol.44 (2), p.133-139

2012

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CSE1L, a novel microvesicle membrane protein, mediates Ras-triggered microvesicle generation and metastasis of tumor cells

Molecular medicine (Cambridge, Mass.), 2012-12, Vol.18 (9), p.1269-1280

2012

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Anaesthesia generates neuronal insulin resistance by inducing hypothermia

BMC neuroscience, 2008-10, Vol.9 (1), p.100-100, Article 100

2008

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snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response

Acta neuropathologica communications, 2024-06, Vol.12 (1), p.102-18, Article 102

2024

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Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma

Nature communications, 2014-12, Vol.5 (1), p.5712-5712, Article 5712

2014

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Context-dependent modulation of aggressiveness of pediatric tumors by individual oncogenic RAS isoforms

Oncogene, 2021-08, Vol.40 (31), p.4955-4966

2021

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Transcriptional activation of the Axl and PDGFR-α by c-Met through a ras- and Src-independent mechanism in human bladder cancer

BMC cancer, 2011-04, Vol.11 (1), p.139-139, Article 139

2011

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ENMD-1198, a novel tubulin-binding agent reduces HIF-1alpha and STAT3 activity in human hepatocellular carcinoma(HCC) cells, and inhibits growth and vascularization in vivo

BMC cancer, 2008-07, Vol.8 (1), p.206-206, Article 206

2008

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The multikinase inhibitor Sorafenib displays significant antiproliferative effects and induces apoptosis via caspase 3, 7 and PARP in B- and T-lymphoblastic cells

BMC cancer, 2010-10, Vol.10 (1), p.560-560, Article 560

2010

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Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses

Nature reviews. Drug discovery, 2007-05, Vol.6 (5), p.391-403

2007

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The ERK MAP kinase-PEA3/ETV4-MMP-1 axis is operative in oesophageal adenocarcinoma

The ERK-ZEB1 pathway mediates epithelial-mesenchymal transition in pemetrexed resistant lung cancer cells with suppression by vinca alkaloids

Lovastatin inhibits erythroleukemia progression through KLF2-mediated suppression of MAPK/ERK signaling

Phosphorylation of cofilin-1 by ERK confers HDAC inhibitor resistance in hepatocellular carcinoma cells via decreased ROS-mediated mitochondria injury

Dopaminergic tone regulates transient potassium current maximal conductance through a translational mechanism requiring D1Rs, cAMP/PKA, Erk and mTOR

BCR ABL and IL-3 activate Rap1 to stimulate the B-Raf MEK Erk and Akt signaling pathways and to regulate proliferation, apoptosis, and adhesion

Common alterations in gene expression and increased proliferation in recurrent acute myeloid leukemia

Axl promotes cell invasion by inducing MMP-9 activity through activation of NF-κB and Brg-1

The leukaemic oncoproteins Bcr-Abl and Tel-Abl (ETV6/Abl) have altered substrate preferences and activate similar intracellular signalling pathways

Time-resolved relaxation and fragmentation of polycyclic aromatic hydrocarbons investigated in the ultrafast XUV-IR regime

Reversal of cocaine―evoked synaptic potentiation resets drug―induced adaptive behaviour

Uncodified Workings and Unworkable Codes: Canadian Federalism and Public Policy

Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP

Inhibition of glioblastoma dispersal by the MEK inhibitor PD0325901

Gain-of-function RAF1 mutations cause Noonan and LEOPARD syndromes with hypertrophic cardiomyopathy

Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma

CSE1L, a novel microvesicle membrane protein, mediates Ras-triggered microvesicle generation and metastasis of tumor cells

Anaesthesia generates neuronal insulin resistance by inducing hypothermia

snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response

Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma

Context-dependent modulation of aggressiveness of pediatric tumors by individual oncogenic RAS isoforms

Transcriptional activation of the Axl and PDGFR-α by c-Met through a ras- and Src-independent mechanism in human bladder cancer

ENMD-1198, a novel tubulin-binding agent reduces HIF-1alpha and STAT3 activity in human hepatocellular carcinoma(HCC) cells, and inhibits growth and vascularization in vivo

The multikinase inhibitor Sorafenib displays significant antiproliferative effects and induces apoptosis via caspase 3, 7 and PARP in B- and T-lymphoblastic cells

Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses

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