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Metabolism and Disposition of Volanesorsen, a 2'- O -(2 methoxyethyl) Antisense Oligonucleotide, Across Species

Drug metabolism and disposition, 2019-10, Vol.47 (10), p.1164-1173

2019

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Predicting drug disposition via application of BCS: transport/absorption/ elimination interplay and development of a biopharmaceutics drug disposition classification system

Pharmaceutical research, 2005-01, Vol.22 (1), p.11-23

2005

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Sex differences in drug disposition

Journal of biomedicine & biotechnology, 2011-01, Vol.2011, p.187103

2011

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The Roles of Xenobiotic Receptors: Beyond Chemical Disposition

Drug metabolism and disposition, 2018-09, Vol.46 (9), p.1361-1371

2018

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Metabolism and Disposition of Acetaminophen: Recent Advances in Relation to Hepatotoxicity and Diagnosis

Pharmaceutical research, 2013-09, Vol.30 (9), p.2174-2187

2013

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Disposition, metabolism and mass balance of [14C]apremilast following oral administration

Xenobiotica, 2011-12, Vol.41 (12), p.1063-1075

2011

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Gender differences in the disposition and toxicity of metals

Environmental research, 2007-05, Vol.104 (1), p.85-95

2007

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Contribution of the Gut Microbiome to Drug Disposition, Pharmacokinetic and Pharmacodynamic Variability

Clinical pharmacokinetics, 2021-08, Vol.60 (8), p.971-984

2021

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Physiology of the Neonatal Gastrointestinal System Relevant to the Disposition of Orally Administered Medications

Drug metabolism and disposition, 2019-03, Vol.47 (3), p.296-313

2019

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Timing in drug absorption and disposition: The past, present, and future of chronopharmacokinetics

British journal of pharmacology, 2020-05, Vol.177 (10), p.2215-2239

2020

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Hepatic Metabolism Affects the Atropselective Disposition of 2,2′,3,3′,6,6′-Hexachlorobiphenyl (PCB 136) in Mice

Environmental science & technology, 2015-01, Vol.49 (1), p.616-625

2015

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Metabolism and Disposition of the Thienopyridine Antiplatelet Drugs Ticlopidine, Clopidogrel, and Prasugrel in Humans

Journal of clinical pharmacology, 2010-02, Vol.50 (2), p.126-142

2010

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Sandwich-Cultured Hepatocytes for Mechanistic Understanding of Hepatic Disposition of Parent Drugs and Metabolites by Transporter-Enzyme Interplay

Drug metabolism and disposition, 2018-05, Vol.46 (5), p.680-691

2018

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An update on the role of intestinal cytochrome P450 enzymes in drug disposition

Acta pharmaceutica Sinica. B, 2016-09, Vol.6 (5), p.374-383

2016

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Transporter-Enzyme Interplay: Deconvoluting Effects of Hepatic Transporters and Enzymes on Drug Disposition Using Static and Dynamic Mechanistic Models

Journal of clinical pharmacology, 2016-07, Vol.56 (S7), p.S99-S109

2016

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Nanotracing and cavity-ring down spectroscopy: A new ultrasensitive approach in large molecule drug disposition studies

PloS one, 2018-10, Vol.13 (10), p.e0205435-e0205435

2018

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Current Understanding of Drug Disposition in Kidney Disease

Journal of clinical pharmacology, 2012-01, Vol.52 (S1), p.10S-22S

2012

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Human tissue-engineered skeletal muscle: a novel 3D in vitro model for drug disposition and toxicity after intramuscular injection

Scientific reports, 2018-08, Vol.8 (1), p.12206-14, Article 12206

2018

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Atomoxetine: A Review of Its Pharmacokinetics and Pharmacogenomics Relative to Drug Disposition

Journal of child and adolescent psychopharmacology, 2016-05, Vol.26 (4), p.314

2016

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In vivo, in vitro and ex vivo models to assess pulmonary absorption and disposition of inhaled therapeutics for systemic delivery

Advanced drug delivery reviews, 2006-10, Vol.58 (9), p.1030-1060

Sakagami, Masahiro

2006

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A Theoretical Physiologically‐Based Pharmacokinetic Approach to Ascertain Covariates Explaining the Large Interpatient Variability in Tacrolimus Disposition

CPT: pharmacometrics and systems pharmacology, 2019-05, Vol.8 (5), p.273-284

2019

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Important role of CYP2J2 in protein kinase inhibitor degradation: a possible role in intratumor drug disposition and resistance

PloS one, 2014-05, Vol.9 (5), p.e95532-e95532

2014

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The effects of pharmaceutical excipients on drug disposition

Advanced drug delivery reviews, 2007-12, Vol.59 (15), p.1482-1503

2007

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Comparative Proteomic Characterization of 4 Human Liver-Derived Single Cell Culture Models Reveals Significant Variation in the Capacity for Drug Disposition, Bioactivation, and Detoxication

Toxicological sciences, 2015-10, Vol.147 (2), p.412-424

2015

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An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug/Drug Interactions, and to Facilitate Design of Clinical Trials

Drug metabolism and disposition, 2019-06, Vol.47 (6), p.601-615

2019

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Metabolism and Disposition of Volanesorsen, a 2'- O -(2 methoxyethyl) Antisense Oligonucleotide, Across Species

Predicting drug disposition via application of BCS: transport/absorption/ elimination interplay and development of a biopharmaceutics drug disposition classification system

Sex differences in drug disposition

The Roles of Xenobiotic Receptors: Beyond Chemical Disposition

Metabolism and Disposition of Acetaminophen: Recent Advances in Relation to Hepatotoxicity and Diagnosis

Disposition, metabolism and mass balance of [14C]apremilast following oral administration

Gender differences in the disposition and toxicity of metals

Contribution of the Gut Microbiome to Drug Disposition, Pharmacokinetic and Pharmacodynamic Variability

Physiology of the Neonatal Gastrointestinal System Relevant to the Disposition of Orally Administered Medications

Timing in drug absorption and disposition: The past, present, and future of chronopharmacokinetics

Hepatic Metabolism Affects the Atropselective Disposition of 2,2′,3,3′,6,6′-Hexachlorobiphenyl (PCB 136) in Mice

Metabolism and Disposition of the Thienopyridine Antiplatelet Drugs Ticlopidine, Clopidogrel, and Prasugrel in Humans

Sandwich-Cultured Hepatocytes for Mechanistic Understanding of Hepatic Disposition of Parent Drugs and Metabolites by Transporter-Enzyme Interplay

An update on the role of intestinal cytochrome P450 enzymes in drug disposition

Transporter-Enzyme Interplay: Deconvoluting Effects of Hepatic Transporters and Enzymes on Drug Disposition Using Static and Dynamic Mechanistic Models

Nanotracing and cavity-ring down spectroscopy: A new ultrasensitive approach in large molecule drug disposition studies

Current Understanding of Drug Disposition in Kidney Disease

Human tissue-engineered skeletal muscle: a novel 3D in vitro model for drug disposition and toxicity after intramuscular injection

Atomoxetine: A Review of Its Pharmacokinetics and Pharmacogenomics Relative to Drug Disposition

In vivo, in vitro and ex vivo models to assess pulmonary absorption and disposition of inhaled therapeutics for systemic delivery

A Theoretical Physiologically‐Based Pharmacokinetic Approach to Ascertain Covariates Explaining the Large Interpatient Variability in Tacrolimus Disposition

Important role of CYP2J2 in protein kinase inhibitor degradation: a possible role in intratumor drug disposition and resistance

The effects of pharmaceutical excipients on drug disposition

Comparative Proteomic Characterization of 4 Human Liver-Derived Single Cell Culture Models Reveals Significant Variation in the Capacity for Drug Disposition, Bioactivation, and Detoxication

An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug/Drug Interactions, and to Facilitate Design of Clinical Trials

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