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Metabolism and Disposition of Volanesorsen, a 2'- O -(2 methoxyethyl) Antisense Oligonucleotide, Across Species

Drug metabolism and disposition, 2019-10, Vol.47 (10), p.1164-1173

2019

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Clinical Applications and the Roles of Transporters in Disposition, Tumor Targeting, and Tissue Toxicity of meta -Iodobenzylguanidine (mIBG)

Drug metabolism and disposition, 2022-09, Vol.50 (9), p.1218-1227

2022

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Disposition and Metabolism of [ 14 C]Lemborexant in Healthy Human Subjects and Characterization of Its Circulating Metabolites

Drug metabolism and disposition, 2021-01, Vol.49 (1), p.31-38

2021

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Phase II Conjugates of Urolithins Isolated from Human Urine and Potential Role of β -Glucuronidases in Their Disposition

Drug metabolism and disposition, 2017-06, Vol.45 (6), p.657-665

2017

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The Nonclinical Disposition and Pharmacokinetic/Pharmacodynamic Properties of N -Acetylgalactosamine-Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in Translation to Human

Drug metabolism and disposition, 2022-06, Vol.50 (6), p.781-797

2022

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Pharmacokinetics, Disposition, and Biotransformation of [ 14 C]Omecamtiv Mecarbil in Healthy Male Subjects after a Single Intravenous or Oral Dose

Drug metabolism and disposition, 2021-08, Vol.49 (8), p.619-628

2021

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Disposition and metabolic profiling of [(14)C]cerlapirdine using accelerator mass spectrometry

Drug metabolism and disposition, 2014-12, Vol.42 (12), p.2023

2014

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Relevance of Human Aldoketoreductases and Microbial β -Glucuronidases in Testosterone Disposition

Drug metabolism and disposition, 2023-04, Vol.51 (4), p.427-435

2023

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The Roles of Xenobiotic Receptors: Beyond Chemical Disposition

Drug metabolism and disposition, 2018-09, Vol.46 (9), p.1361-1371

2018

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Metabolism and Disposition of [ 14 C]Pevonedistat, a First-In-Class NEDD8 ‑Activating Enzyme Inhibitor, After Intravenous Infusion to Patients With Advanced Solid Tumors

Drug metabolism and disposition, 2022-07, Vol.50 (7), p.989-997

2022

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Hepatic Enzymes Relevant to the Disposition of (-)-∆ 9 -Tetrahydrocannabinol (THC) and Its Psychoactive Metabolite, 11-OH-THC

Drug metabolism and disposition, 2019-03, Vol.47 (3), p.249-256

2019

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Pharmacokinetics and Disposition of Momelotinib Revealed a Disproportionate Human Metabolite-Resolution for Clinical Development

Drug metabolism and disposition, 2018-03, Vol.46 (3), p.237-247

2018

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Pharmacogenetic Influence on Stereoselective Steady-State Disposition of Bupropion

Drug metabolism and disposition, 2024-04, Vol.52 (5), p.455

2024

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Effect of Size on Solid Tumor Disposition of Protein Therapeutics

Drug metabolism and disposition, 2019-10, Vol.47 (10), p.1136-1145

2019

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Vincristine Disposition and Neurotoxicity Are Unchanged in Humanized CYP3A5 Mice

Drug metabolism and disposition, 2024-02, Vol.52 (2), p.80

2024

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Special Section on Perspectives on Drug Metabolism and Disposition, Part II-Editorial

Drug metabolism and disposition, 2023-08, Vol.51 (8), p.902

2023

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Special Section on Perspectives on Drug Metabolism and Disposition, Part I-Editorial

Drug metabolism and disposition, 2023-06, Vol.51 (6), p.645

2023

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The Evolution of Drug Metabolism and Disposition : A Perspective From the Editors

Drug metabolism and disposition, 2023-01, Vol.51 (1), p.105-110

2023

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Mechanisms Influencing the Pharmacokinetics and Disposition of Monoclonal Antibodies and Peptides

Drug metabolism and disposition, 2019-10, Vol.47 (10), p.1100-1110

Datta-Mannan, Amita

2019

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Mechanistic Modeling of Pitavastatin Disposition in Sandwich-Cultured Human Hepatocytes: A Proteomics-Informed Bottom-Up Approach

Drug metabolism and disposition, 2016-04, Vol.44 (4), p.505-516

2016

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Edoxaban transport via P-glycoprotein is a key factor for the drug's disposition

Drug metabolism and disposition, 2014-04, Vol.42 (4), p.520

2014

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Sorafenib hepatobiliary disposition: mechanisms of hepatic uptake and disposition of generated metabolites

Drug metabolism and disposition, 2013-06, Vol.41 (6), p.1179

2013

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Drug Transporters in Xenobiotic Disposition and Pharmacokinetic Prediction

Drug metabolism and disposition, 2018-05, Vol.46 (5), p.561-566

2018

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Disposition of Nirmatrelvir, an Orally Bioavailable Inhibitor of SARS-CoV-2 3C-Like Protease, across Animals and Humans

Drug metabolism and disposition, 2022-05, Vol.50 (5), p.576-590

2022

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Absorption, Metabolism, Excretion, and the Contribution of Intestinal Metabolism to the Oral Disposition of [14C]Cobimetinib, a MEK Inhibitor, in Humans

Drug metabolism and disposition, 2016-01, Vol.44 (1), p.28-39

2016

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Metabolism and Disposition of Volanesorsen, a 2'- O -(2 methoxyethyl) Antisense Oligonucleotide, Across Species

Clinical Applications and the Roles of Transporters in Disposition, Tumor Targeting, and Tissue Toxicity of meta -Iodobenzylguanidine (mIBG)

Disposition and Metabolism of [ 14 C]Lemborexant in Healthy Human Subjects and Characterization of Its Circulating Metabolites

Phase II Conjugates of Urolithins Isolated from Human Urine and Potential Role of β -Glucuronidases in Their Disposition

The Nonclinical Disposition and Pharmacokinetic/Pharmacodynamic Properties of N -Acetylgalactosamine-Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in Translation to Human

Pharmacokinetics, Disposition, and Biotransformation of [ 14 C]Omecamtiv Mecarbil in Healthy Male Subjects after a Single Intravenous or Oral Dose

Disposition and metabolic profiling of [(14)C]cerlapirdine using accelerator mass spectrometry

Relevance of Human Aldoketoreductases and Microbial β -Glucuronidases in Testosterone Disposition

The Roles of Xenobiotic Receptors: Beyond Chemical Disposition

Metabolism and Disposition of [ 14 C]Pevonedistat, a First-In-Class NEDD8 ‑Activating Enzyme Inhibitor, After Intravenous Infusion to Patients With Advanced Solid Tumors

Hepatic Enzymes Relevant to the Disposition of (-)-∆ 9 -Tetrahydrocannabinol (THC) and Its Psychoactive Metabolite, 11-OH-THC

Pharmacokinetics and Disposition of Momelotinib Revealed a Disproportionate Human Metabolite-Resolution for Clinical Development

Pharmacogenetic Influence on Stereoselective Steady-State Disposition of Bupropion

Effect of Size on Solid Tumor Disposition of Protein Therapeutics

Vincristine Disposition and Neurotoxicity Are Unchanged in Humanized CYP3A5 Mice

Special Section on Perspectives on Drug Metabolism and Disposition, Part II-Editorial

Special Section on Perspectives on Drug Metabolism and Disposition, Part I-Editorial

The Evolution of Drug Metabolism and Disposition : A Perspective From the Editors

Mechanisms Influencing the Pharmacokinetics and Disposition of Monoclonal Antibodies and Peptides

Mechanistic Modeling of Pitavastatin Disposition in Sandwich-Cultured Human Hepatocytes: A Proteomics-Informed Bottom-Up Approach

Edoxaban transport via P-glycoprotein is a key factor for the drug's disposition

Sorafenib hepatobiliary disposition: mechanisms of hepatic uptake and disposition of generated metabolites

Drug Transporters in Xenobiotic Disposition and Pharmacokinetic Prediction

Disposition of Nirmatrelvir, an Orally Bioavailable Inhibitor of SARS-CoV-2 3C-Like Protease, across Animals and Humans

Absorption, Metabolism, Excretion, and the Contribution of Intestinal Metabolism to the Oral Disposition of [14C]Cobimetinib, a MEK Inhibitor, in Humans

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