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Effect of cyclodextrin concentration on the oral bioavailability of danazol and cinnarizine in rats

European journal of pharmaceutics and biopharmaceutics, 2016-04, Vol.101, p.9-14

2016

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Simultaneous lipolysis/permeation in vitro model, for the estimation of bioavailability of lipid based drug delivery systems

European journal of pharmaceutics and biopharmaceutics, 2017-08, Vol.117, p.300-307

2017

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In Vitro Digestion–In Situ Absorption Setup Employing a Physiologically Relevant Value of the Membrane Surface Area/Volume Ratio for Evaluating Performance of Lipid-Based Formulations: A Comparative Study with an In Vitro Digestion–Permeation Model

Molecular pharmaceutics, 2024-07, Vol.21 (7), p.3459-3470

2024

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Efficacy and Safety of Cinnarizine in the Prophylaxis of Migraine in Children: A Double-Blind Placebo-Controlled Randomized Trial

Pediatric neurology, 2014-10, Vol.51 (4), p.503-508

2014

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Formulation and Characterization of Cinnarizine Targeted Aural Transfersomal Gel for Vertigo Treatment: A Pharmacokinetic Study on Rabbits

International journal of nanomedicine, 2020-01, Vol.15, p.6211-6223

2020

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Oral bioavailability of cinnarizine in dogs: Relation to SNEDDS droplet size, drug solubility and in vitro precipitation

European journal of pharmaceutical sciences, 2013-01, Vol.48 (1-2), p.339-350

2013

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Effect of food intake and co-administration of placebo self-nanoemulsifying drug delivery systems on the absorption of cinnarizine in healthy human volunteers

European journal of pharmaceutical sciences, 2016-03, Vol.84, p.77-82

2016

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Ufasomes nano-vesicles-based lyophilized platforms for intranasal delivery of cinnarizine: preparation, optimization, ex-vivo histopathological safety assessment and mucosal confocal imaging

Pharmaceutical development and technology, 2016-09, Vol.21 (6), p.706-715

2016

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Intratympanic injections of emulsion-like dispersions to augment cinnarizine amount in a healthy rabbit inner ear model

Nanomedicine (London, England), 2024, Vol.19 (21-22), p.1717-25

2024

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Cinnarizine food-effects in beagle dogs can be avoided by administration in a Self Nano Emulsifying Drug Delivery System (SNEDDS)

European journal of pharmaceutical sciences, 2014-06, Vol.57, p.164-172

2014

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A lipid-based liquid crystalline matrix that provides sustained release and enhanced oral bioavailability for a model poorly water soluble drug in rats

International journal of pharmaceutics, 2007-08, Vol.340 (1), p.52-60

2007

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Solution or suspension – Does it matter for lipid based systems? In vivo studies of chase dosing lipid vehicles with aqueous suspensions of a poorly soluble drug

European journal of pharmaceutics and biopharmaceutics, 2017-08, Vol.117, p.308-314

2017

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Fed and fasted state gastro-intestinal in vitro lipolysis: In vitro in vivo relations of a conventional tablet, a SNEDDS and a solidified SNEDDS

European journal of pharmaceutical sciences, 2014-06, Vol.57, p.232-239

2014

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ChlorTox scale assessment, greenness, and whiteness evaluation of selective spectrophotometric analysis of dimenhydrinate and cinnarizine

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2024-11, Vol.321, p.124740, Article 124740

2024

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Transformation of Poorly Water-Soluble Drugs into Lipophilic Ionic Liquids Enhances Oral Drug Exposure from Lipid Based Formulations

Molecular pharmaceutics, 2015-06, Vol.12 (6), p.1980-1991

2015

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Prediction of oral absorption of cinnarizine – A highly supersaturating poorly soluble weak base with borderline permeability

European journal of pharmaceutics and biopharmaceutics, 2014-11, Vol.88 (3), p.795-806

2014

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Development of a high-throughput in vitro intestinal lipolysis model for rapid screening of lipid-based drug delivery systems

European journal of pharmaceutics and biopharmaceutics, 2015-08, Vol.94, p.493-500

2015

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Influence of drug load and physical form of cinnarizine in new SNEDDS dosing regimens: in vivo and in vitro evaluations

The AAPS journal, 2017-03, Vol.19 (2), p.587-594

2017

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Continuous Synthesis of Cinnarizine Salt with Malic Acid by Applying Green Chemistry Using Water-Assisted Twin Screw Extrusion

Molecular pharmaceutics, 2023-10, Vol.20 (10), p.5160-5172

2023

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Novel Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) for Oral Delivery of Cinnarizine: Design, Optimization, and In-Vitro Assessment

AAPS PharmSciTech, 2012-09, Vol.13 (3), p.967-977

2012

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Bioavailability of Cinnarizine in Dogs: Effect of SNEDDS Loading Level and Correlation with Cinnarizine Solubilization During In Vitro Lipolysis

Pharmaceutical research, 2013-12, Vol.30 (12), p.3101-3113

2013

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Small molecules bind human mTOR protein and inhibit mTORC1 specifically

Biochemical pharmacology, 2018-09, Vol.155, p.298-304

2018

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In vivo evaluation of supersaturation/precipitation/re-dissolution behavior of cinnarizine, a lipophilic weak base, in the gastrointestinal tract: the key process of oral absorption

European journal of pharmaceutical sciences, 2017-01, Vol.96, p.464-471

2017

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Experiencia clínica con la combinación de cinarizina y dimenhidrinato en el tratamiento del vértigo de origen diverso en atención primaria: una serie de casos

Medicina Clínica Práctica, 2024-10, Vol.7 (4), p.100457

2024

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Intestinal Bile Secretion Promotes Drug Absorption from Lipid Colloidal Phases via Induction of Supersaturation

Molecular pharmaceutics, 2013-05, Vol.10 (5), p.1874-1889

2013

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Effect of cyclodextrin concentration on the oral bioavailability of danazol and cinnarizine in rats

Simultaneous lipolysis/permeation in vitro model, for the estimation of bioavailability of lipid based drug delivery systems

In Vitro Digestion–In Situ Absorption Setup Employing a Physiologically Relevant Value of the Membrane Surface Area/Volume Ratio for Evaluating Performance of Lipid-Based Formulations: A Comparative Study with an In Vitro Digestion–Permeation Model

Efficacy and Safety of Cinnarizine in the Prophylaxis of Migraine in Children: A Double-Blind Placebo-Controlled Randomized Trial

Formulation and Characterization of Cinnarizine Targeted Aural Transfersomal Gel for Vertigo Treatment: A Pharmacokinetic Study on Rabbits

Oral bioavailability of cinnarizine in dogs: Relation to SNEDDS droplet size, drug solubility and in vitro precipitation

Effect of food intake and co-administration of placebo self-nanoemulsifying drug delivery systems on the absorption of cinnarizine in healthy human volunteers

Ufasomes nano-vesicles-based lyophilized platforms for intranasal delivery of cinnarizine: preparation, optimization, ex-vivo histopathological safety assessment and mucosal confocal imaging

Intratympanic injections of emulsion-like dispersions to augment cinnarizine amount in a healthy rabbit inner ear model

Cinnarizine food-effects in beagle dogs can be avoided by administration in a Self Nano Emulsifying Drug Delivery System (SNEDDS)

A lipid-based liquid crystalline matrix that provides sustained release and enhanced oral bioavailability for a model poorly water soluble drug in rats

Solution or suspension – Does it matter for lipid based systems? In vivo studies of chase dosing lipid vehicles with aqueous suspensions of a poorly soluble drug

Fed and fasted state gastro-intestinal in vitro lipolysis: In vitro in vivo relations of a conventional tablet, a SNEDDS and a solidified SNEDDS

ChlorTox scale assessment, greenness, and whiteness evaluation of selective spectrophotometric analysis of dimenhydrinate and cinnarizine

Transformation of Poorly Water-Soluble Drugs into Lipophilic Ionic Liquids Enhances Oral Drug Exposure from Lipid Based Formulations

Prediction of oral absorption of cinnarizine – A highly supersaturating poorly soluble weak base with borderline permeability

Development of a high-throughput in vitro intestinal lipolysis model for rapid screening of lipid-based drug delivery systems

Influence of drug load and physical form of cinnarizine in new SNEDDS dosing regimens: in vivo and in vitro evaluations

Continuous Synthesis of Cinnarizine Salt with Malic Acid by Applying Green Chemistry Using Water-Assisted Twin Screw Extrusion

Novel Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) for Oral Delivery of Cinnarizine: Design, Optimization, and In-Vitro Assessment

Bioavailability of Cinnarizine in Dogs: Effect of SNEDDS Loading Level and Correlation with Cinnarizine Solubilization During In Vitro Lipolysis

Small molecules bind human mTOR protein and inhibit mTORC1 specifically

In vivo evaluation of supersaturation/precipitation/re-dissolution behavior of cinnarizine, a lipophilic weak base, in the gastrointestinal tract: the key process of oral absorption

Experiencia clínica con la combinación de cinarizina y dimenhidrinato en el tratamiento del vértigo de origen diverso en atención primaria: una serie de casos

Intestinal Bile Secretion Promotes Drug Absorption from Lipid Colloidal Phases via Induction of Supersaturation

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