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Abstract 2073 KNOCKDOWN OF CES1 IN THP-1 MACROPHAGES PROMOTES A PROINFLAMMATORY PHENOTYPE

The Journal of biological chemistry, 2024-03, Vol.300 (3), p.106387, Article 106387

2024

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Prediction and In Vitro Evaluation of Selected Protease Inhibitor Antiviral Drugs as Inhibitors of Carboxylesterase 1: A Potential Source of Drug-Drug Interactions

Pharmaceutical research, 2012-04, Vol.29 (4), p.972-982

2012

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Dabigatran etexilate activation is affected by the CES1 genetic polymorphism G143E (rs71647871) and gender

Biochemical pharmacology, 2016-11, Vol.119, p.76-84

2016

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Proteomic and metabolomic responses in hepatopancreas of whiteleg shrimp Litopenaeus vannamei infected by microsporidian Enterocytozoon hepatopenaei

Fish & shellfish immunology, 2019-04, Vol.87, p.534-545

2019

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A red emission multiple detection site probe for detecting carboxylesterase 1 based on BODIPY fluorophore

Journal of photochemistry and photobiology. A, Chemistry., 2021-12, Vol.421, p.113516, Article 113516

2021

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Construction of a red emission fluorescent protein chromophore-based probe for detection of carboxylesterase 1 and carbamate pesticide in culture cells

Talanta (Oxford), 2021-02, Vol.223 (Pt 2), p.121744-121744, Article 121744

2021

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A magnetic SERS immunosensor for highly sensitive and selective detection of human carboxylesterase 1 in human serum samples

Analytica chimica acta, 2020-02, Vol.1097, p.176-185

2020

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Lysosome targeting metal-organic framework probe LysFP@ZIF-8 for highly sensitive quantification of carboxylesterase 1 and organophosphates in living cells

Journal of hazardous materials, 2021-04, Vol.407, p.124342-124342, Article 124342

2021

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Quantitative evaluation of human carboxylesterase 1 by SERS-ELISA using a synergistic enhancement strategy based on gold nanoparticles and metal–organic framework

Microchemical journal, 2022-12, Vol.183, p.108114, Article 108114

2022

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Detection of carboxylesterase 1 and carbamates with a novel fluorescent protein chromophore based probe

Dyes and pigments, 2021-08, Vol.192, p.109444, Article 109444

2021

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Identification of regulatory variants of carboxylesterase 1 (CES1): A proof‐of‐concept study for the application of the Allele‐Specific Protein Expression (ASPE) assay in identifying cis‐acting regulatory genetic polymorphisms

Proteomics (Weinheim), 2023-01, Vol.23 (1), p.e2200176-n/a

2023

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ABCB1 attenuates brain exposure to the KRASG12C inhibitor opnurasib whereas binding to mouse carboxylesterase 1c influences its plasma exposure

Biomedicine & pharmacotherapy, 2024-06, Vol.175, p.116720, Article 116720

2024

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Construction of selectively enhanced MOF-SERS sensor and highly sensitive detection of hCE1 in HepG2 cells

Microchemical journal, 2024-07, Vol.202, p.110776, Article 110776

2024

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Discovery of triterpenoids as potent dual inhibitors of pancreatic lipase and human carboxylesterase 1

Journal of enzyme inhibition and medicinal chemistry, 2022-12, Vol.37 (1), p.629-640

2022

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Involvement of esterases in the pulmonary metabolism of beclomethasone dipropionate and the potential influence of cannabis use

Chemico-biological interactions, 2022-12, Vol.368, p.110228-110228, Article 110228

2022

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Detection of Carboxylesterase 1 and Chlorpyrifos with ZIF‑8 Metal–Organic Frameworks Using a Red Emission BODIPY-Based Probe

ACS applied materials & interfaces, 2021-02, Vol.13 (7), p.8718-8726

2021

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Pyrazolone compounds could inhibit CES1 and ameliorates fat accumulation during adipocyte differentiation

Bioorganic chemistry, 2024-09, Vol.150, p.107536, Article 107536

2024

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Pharmacokinetics of the KRASG12C inhibitor adagrasib is limited by CYP3A and ABCB1, and influenced by binding to mouse plasma carboxylesterase 1c

Biomedicine & pharmacotherapy, 2023-10, Vol.166, p.115304-115304, Article 115304

2023

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Assessment of the inhibitory effects of pyrethroids against human carboxylesterases

Toxicology and applied pharmacology, 2017-04, Vol.321, p.48-56

2017

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Structure-Activity Relationships of Pentacyclic Triterpenoids as Potent and Selective Inhibitors against Human Carboxylesterase 1

Frontiers in pharmacology, 2017-06, Vol.8, p.435-435

2017

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Catalytic hydrolysis mechanism of aminocarboxylester substrate by human carboxylesterase 1: A theoretical study on methylphenidate hydrolysis

Computational and theoretical chemistry, 2021-05, Vol.1199, p.113198, Article 113198

2021

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Cisplatin increases carboxylesterases through increasing PXR mediated by the decrease of DEC1

Journal of biomedical research, 2023-11, Vol.37 (6), p.431-447

2023

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Nevadensin is a naturally occurring selective inhibitor of human carboxylesterase 1

International journal of biological macromolecules, 2018-12, Vol.120 (Pt B), p.1944-1954

2018

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Choline and trimethylamine N-oxide impair metabolic activation of and platelet response to clopidogrel through activation of the NOX/ROS/Nrf2/CES1 pathway

Journal of thrombosis and haemostasis, 2023-01, Vol.21 (1), p.117-132

2023

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High-resolution structural-omics of human liver enzymes

Cell reports (Cambridge), 2023-06, Vol.42 (6), p.112609-112609, Article 112609

2023

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Abstract 2073 KNOCKDOWN OF CES1 IN THP-1 MACROPHAGES PROMOTES A PROINFLAMMATORY PHENOTYPE

Prediction and In Vitro Evaluation of Selected Protease Inhibitor Antiviral Drugs as Inhibitors of Carboxylesterase 1: A Potential Source of Drug-Drug Interactions

Dabigatran etexilate activation is affected by the CES1 genetic polymorphism G143E (rs71647871) and gender

Proteomic and metabolomic responses in hepatopancreas of whiteleg shrimp Litopenaeus vannamei infected by microsporidian Enterocytozoon hepatopenaei

A red emission multiple detection site probe for detecting carboxylesterase 1 based on BODIPY fluorophore

Construction of a red emission fluorescent protein chromophore-based probe for detection of carboxylesterase 1 and carbamate pesticide in culture cells

A magnetic SERS immunosensor for highly sensitive and selective detection of human carboxylesterase 1 in human serum samples

Lysosome targeting metal-organic framework probe LysFP@ZIF-8 for highly sensitive quantification of carboxylesterase 1 and organophosphates in living cells

Quantitative evaluation of human carboxylesterase 1 by SERS-ELISA using a synergistic enhancement strategy based on gold nanoparticles and metal–organic framework

Detection of carboxylesterase 1 and carbamates with a novel fluorescent protein chromophore based probe

Identification of regulatory variants of carboxylesterase 1 (CES1): A proof‐of‐concept study for the application of the Allele‐Specific Protein Expression (ASPE) assay in identifying cis‐acting regulatory genetic polymorphisms

ABCB1 attenuates brain exposure to the KRASG12C inhibitor opnurasib whereas binding to mouse carboxylesterase 1c influences its plasma exposure

Construction of selectively enhanced MOF-SERS sensor and highly sensitive detection of hCE1 in HepG2 cells

Discovery of triterpenoids as potent dual inhibitors of pancreatic lipase and human carboxylesterase 1

Involvement of esterases in the pulmonary metabolism of beclomethasone dipropionate and the potential influence of cannabis use

Detection of Carboxylesterase 1 and Chlorpyrifos with ZIF‑8 Metal–Organic Frameworks Using a Red Emission BODIPY-Based Probe

Pyrazolone compounds could inhibit CES1 and ameliorates fat accumulation during adipocyte differentiation

Pharmacokinetics of the KRASG12C inhibitor adagrasib is limited by CYP3A and ABCB1, and influenced by binding to mouse plasma carboxylesterase 1c

Assessment of the inhibitory effects of pyrethroids against human carboxylesterases

Structure-Activity Relationships of Pentacyclic Triterpenoids as Potent and Selective Inhibitors against Human Carboxylesterase 1

Catalytic hydrolysis mechanism of aminocarboxylester substrate by human carboxylesterase 1: A theoretical study on methylphenidate hydrolysis

Cisplatin increases carboxylesterases through increasing PXR mediated by the decrease of DEC1

Nevadensin is a naturally occurring selective inhibitor of human carboxylesterase 1

Choline and trimethylamine N-oxide impair metabolic activation of and platelet response to clopidogrel through activation of the NOX/ROS/Nrf2/CES1 pathway

High-resolution structural-omics of human liver enzymes

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