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Thrombopoiesis is spatially regulated by the bone marrow vasculature

Nature communications, 2017-07, Vol.8 (1), p.127-11, Article 127

2017

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SDF-1 dynamically mediates megakaryocyte niche occupancy and thrombopoiesis at steady state and following radiation injury

Blood, 2014-07, Vol.124 (2), p.277-286

2014

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The Coagulation and Immune Systems Are Directly Linked through the Activation of Interleukin-1α by Thrombin

Immunity (Cambridge, Mass.), 2019-04, Vol.50 (4), p.1033-1042.e6

2019

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β4GALT1 controls β1 integrin function to govern thrombopoiesis and hematopoietic stem cell homeostasis

Nature communications, 2020-01, Vol.11 (1), p.356-356, Article 356

2020

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Sugar and spike: not so nice

Blood, 2021-10, Vol.138 (16), p.1386-1387

McKenzie, Steven E.

2021

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Talin-1 is the principal platelet Rap1 effector of integrin activation

Blood, 2020-09, Vol.136 (10), p.1180-1190

2020

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Interpreting the developmental dance of the megakaryocyte: a review of the cellular and molecular processes mediating platelet formation

British journal of haematology, 2014-04, Vol.165 (2), p.227-236

2014

Volltextzugriff (PDF)

CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development

Blood, 2012-02, Vol.119 (7), p.1747-1756

2012

Volltextzugriff (PDF)

Procoagulant platelet sentinels prevent inflammatory bleeding through GPIIBIIIA and GPVI

Blood, 2022-07, Vol.140 (2), p.121-139

2022

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High c-Kit expression identifies hematopoietic stem cells with impaired self-renewal and megakaryocytic bias

The Journal of experimental medicine, 2014-02, Vol.211 (2), p.217-231

2014

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Programmable 3D silk bone marrow niche for platelet generation ex vivo and modeling of megakaryopoiesis pathologies

Blood, 2015-04, Vol.125 (14), p.2254-2264

2015

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RUNX1-deficient human megakaryocytes demonstrate thrombopoietic and platelet half-life and functional defects

Blood, 2023-01, Vol.141 (3), p.260-270

2023

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In-depth PtdIns(3,4,5)P3 signalosome analysis identifies DAPP1 as a negative regulator of GPVI-driven platelet function

Blood advances, 2017-06, Vol.1 (14), p.918-932

2017

Volltextzugriff (PDF)

Megakaryocyte-specific deletion of the protein-tyrosine phosphatases Shp1 and Shp2 causes abnormal megakaryocyte development, platelet production, and function

Blood, 2013-05, Vol.121 (20), p.4205-4220

2013

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Estrogen promotes megakaryocyte polyploidization via estrogen receptor beta-mediated transcription of GATA1

Leukemia, 2017-04, Vol.31 (4), p.945-956

2017

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A novel role of sphingosine 1-phosphate receptor S1pr1 in mouse thrombopoiesis

The Journal of experimental medicine, 2012-11, Vol.209 (12), p.2165-2181

2012

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Melatonin enhances thrombopoiesis through ERK1/2 and Akt activation orchestrated by dual adaptor for phosphotyrosine and 3‐phosphoinositides

Journal of pineal research, 2020-04, Vol.68 (3), p.e12637-n/a

2020

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FlnA-null megakaryocytes prematurely release large and fragile platelets that circulate poorly

Blood, 2011-08, Vol.118 (8), p.2285-2295

2011

Volltextzugriff (PDF)

Excessive serine from the bone marrow microenvironment impairs megakaryopoiesis and thrombopoiesis in Multiple Myeloma

Nature communications, 2023-04, Vol.14 (1), p.2093-2093, Article 2093

2023

Volltextzugriff (PDF)

Functional redundancy between RAP1 isoforms in murine platelet production and function

Blood, 2018-11, Vol.132 (18), p.1951-1962

2018

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Platelet gene expression and function in patients with COVID-19

Blood, 2020-09, Vol.136 (11), p.1317-1329

2020

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The RNA-binding protein SRSF3 has an essential role in megakaryocyte maturation and platelet production

Blood, 2022-03, Vol.139 (9), p.1359-1373

2022

Volltextzugriff (PDF)

JAK2V617F leads to intrinsic changes in platelet formation and reactivity in a knock-in mouse model of essential thrombocythemia

Blood, 2013-11, Vol.122 (23), p.3787-3797

2013

Volltextzugriff (PDF)

miR-125a-5p regulates megakaryocyte proplatelet formation via the actin-bundling protein L-plastin

Blood, 2020-10, Vol.136 (15), p.1760-1772

2020

Volltextzugriff (PDF)

A let-7 microRNA-RALB axis links the immune properties of iPSC-derived megakaryocytes with platelet producibility

Nature communications, 2024-03, Vol.15 (1), p.2588-2588, Article 2588

2024

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Thrombopoiesis is spatially regulated by the bone marrow vasculature

SDF-1 dynamically mediates megakaryocyte niche occupancy and thrombopoiesis at steady state and following radiation injury

The Coagulation and Immune Systems Are Directly Linked through the Activation of Interleukin-1α by Thrombin

β4GALT1 controls β1 integrin function to govern thrombopoiesis and hematopoietic stem cell homeostasis

Sugar and spike: not so nice

Talin-1 is the principal platelet Rap1 effector of integrin activation

Interpreting the developmental dance of the megakaryocyte: a review of the cellular and molecular processes mediating platelet formation

CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development

Procoagulant platelet sentinels prevent inflammatory bleeding through GPIIBIIIA and GPVI

High c-Kit expression identifies hematopoietic stem cells with impaired self-renewal and megakaryocytic bias

Programmable 3D silk bone marrow niche for platelet generation ex vivo and modeling of megakaryopoiesis pathologies

RUNX1-deficient human megakaryocytes demonstrate thrombopoietic and platelet half-life and functional defects

In-depth PtdIns(3,4,5)P3 signalosome analysis identifies DAPP1 as a negative regulator of GPVI-driven platelet function

Megakaryocyte-specific deletion of the protein-tyrosine phosphatases Shp1 and Shp2 causes abnormal megakaryocyte development, platelet production, and function

Estrogen promotes megakaryocyte polyploidization via estrogen receptor beta-mediated transcription of GATA1

A novel role of sphingosine 1-phosphate receptor S1pr1 in mouse thrombopoiesis

Melatonin enhances thrombopoiesis through ERK1/2 and Akt activation orchestrated by dual adaptor for phosphotyrosine and 3‐phosphoinositides

FlnA-null megakaryocytes prematurely release large and fragile platelets that circulate poorly

Excessive serine from the bone marrow microenvironment impairs megakaryopoiesis and thrombopoiesis in Multiple Myeloma

Functional redundancy between RAP1 isoforms in murine platelet production and function

Platelet gene expression and function in patients with COVID-19

The RNA-binding protein SRSF3 has an essential role in megakaryocyte maturation and platelet production

JAK2V617F leads to intrinsic changes in platelet formation and reactivity in a knock-in mouse model of essential thrombocythemia

miR-125a-5p regulates megakaryocyte proplatelet formation via the actin-bundling protein L-plastin

A let-7 microRNA-RALB axis links the immune properties of iPSC-derived megakaryocytes with platelet producibility

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