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25-Hydroxyvitamin D-24-hydroxylase (CYP24A1): Its important role in the degradation of vitamin D

Archives of biochemistry and biophysics, 2012-07, Vol.523 (1), p.9-18

2012

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Cytochrome P450-mediated metabolism of vitamin D

Journal of lipid research, 2014-01, Vol.55 (1), p.13-31

2014

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CYP90A1/CPD, a Brassinosteroid Biosynthetic Cytochrome P450 of Arabidopsis, Catalyzes C-3 Oxidation

The Journal of biological chemistry, 2012-09, Vol.287 (37), p.31551-31560

2012

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Kinetics of cytochrome P450 3A4 inhibition by heterocyclic drugs defines a general sequential multistep binding process

The Journal of biological chemistry, 2021-01, Vol.296, p.100223, Article 100223

2021

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Cholesterol 24-hydroxylase: an enzyme of cholesterol turnover in the brain

Annual review of biochemistry, 2009-01, Vol.78 (1), p.1017-1040

2009

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IL-1β/TNF-α/IL-6 inflammatory cytokines promote STAT1-dependent induction of CH25H in Zika virus–infected human macrophages

The Journal of biological chemistry, 2019-10, Vol.294 (40), p.14591-14602

2019

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Pharmacologic Stimulation of Cytochrome P450 46A1 and Cerebral Cholesterol Turnover in Mice

The Journal of biological chemistry, 2014-02, Vol.289 (6), p.3529-3538

2014

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Heteroaryl-Substituted Naphthalenes and Structurally Modified Derivatives: Selective Inhibitors of CYP11B2 for the Treatment of Congestive Heart Failure and Myocardial Fibrosis

Journal of medicinal chemistry, 2005-10, Vol.48 (21), p.6632-6642

2005

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Multiplicity of 3-Ketosteroid-9α-Hydroxylase Enzymes in Rhodococcus rhodochrous DSM43269 for Specific Degradation of Different Classes of Steroids

Journal of Bacteriology, 2011-08, Vol.193 (15), p.3931-3940

2011

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Mycobacterium tuberculosis CYP125A1, a steroid C27 monooxygenase that detoxifies intracellularly generated cholest-4-en-3-one

Molecular microbiology, 2010-08, Vol.77 (3), p.730-742

2010

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Characterization of two steroid hydroxylases from different Streptomyces spp. and their ligand‐bound and ‐unbound crystal structures

The FEBS journal, 2019-05, Vol.286 (9), p.1683-1699

2019

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Genetic and structural analyses of cytochrome P450 hydroxylases in sex hormone biosynthesis: Sequential origin and subsequent coevolution

Molecular phylogenetics and evolution, 2016-01, Vol.94 (Pt B), p.676-687

2016

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Crystal Structure of CYP24A1, a Mitochondrial Cytochrome P450 Involved in Vitamin D Metabolism

Journal of molecular biology, 2010-02, Vol.396 (2), p.441-451

2010

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Interaction of Apo-cytochrome b5 with Cytochromes P4503A4 and P45017A: Relevance of Heme Transfer Reactions

Biochemistry (Easton), 2001-04, Vol.40 (16), p.5018-5031

2001

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Antifungal Azoles: Structural Insights into Undesired Tight Binding to Cholesterol-Metabolizing CYP46A1

Molecular pharmacology, 2013-07, Vol.84 (1), p.86-94

2013

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Orphan Nuclear Receptor RORα Regulates Enzymatic Metabolism of Cerebral 24S-Hydroxycholesterol through CYP39A1 Intronic Response Element Activation

International journal of molecular sciences, 2020-05, Vol.21 (9), p.3309

2020

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Structure–function analysis for the hydroxylation of Δ4 C21‐steroids by the myxobacterial CYP260B1

FEBS letters, 2016-06, Vol.590 (12), p.1838-1851

2016

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Possible involvement of pregnane X receptor-enhanced CYP24 expression in drug-induced osteomalacia

The Journal of clinical investigation, 2005-01, Vol.115 (1), p.177-86

2005

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Oxidation of 7-dehydrocholesterol and desmosterol by human cytochrome P450 46A1[S]

Journal of lipid research, 2014-09, Vol.55 (9), p.1933-1943

2014

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Ordered chimerogenesis applied to CYP2B P450 enzymes

Biochimica et biophysica acta, 2016-07, Vol.1860 (7), p.1395-1403

2016

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Human steroid and oxysterol 7α‐hydroxylase CYP7B1: substrate specificity, azole binding and misfolding of clinically relevant mutants

The FEBS journal, 2014-03, Vol.281 (6), p.1700-1713

2014

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Exploring the structural basis of substrate preferences in Baeyer-Villiger monooxygenases: insight from steroid monooxygenase

The Journal of biological chemistry, 2012-06, Vol.287 (27), p.22626-22634

2012

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In Vitro and in Silico Analyses for Predicting Hepatic Cytochrome P450-Dependent Metabolic Potencies of Polychlorinated Biphenyls in the Baikal Seal

Environmental science & technology, 2015-12, Vol.49 (24), p.14588-14596

2015

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Structural Basis of Drug Binding to CYP46A1, an Enzyme That Controls Cholesterol Turnover in the Brain

The Journal of biological chemistry, 2010-10, Vol.285 (41), p.31783-31795

2010

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Structural and Dynamic Basis of Human Cytochrome P450 7B1: A Survey of Substrate Selectivity and Major Active Site Access Channels

Chemistry : a European journal, 2013-01, Vol.19 (2), p.549-557

2013

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25-Hydroxyvitamin D-24-hydroxylase (CYP24A1): Its important role in the degradation of vitamin D

Cytochrome P450-mediated metabolism of vitamin D

CYP90A1/CPD, a Brassinosteroid Biosynthetic Cytochrome P450 of Arabidopsis, Catalyzes C-3 Oxidation

Kinetics of cytochrome P450 3A4 inhibition by heterocyclic drugs defines a general sequential multistep binding process

Cholesterol 24-hydroxylase: an enzyme of cholesterol turnover in the brain

IL-1β/TNF-α/IL-6 inflammatory cytokines promote STAT1-dependent induction of CH25H in Zika virus–infected human macrophages

Pharmacologic Stimulation of Cytochrome P450 46A1 and Cerebral Cholesterol Turnover in Mice

Heteroaryl-Substituted Naphthalenes and Structurally Modified Derivatives: Selective Inhibitors of CYP11B2 for the Treatment of Congestive Heart Failure and Myocardial Fibrosis

Multiplicity of 3-Ketosteroid-9α-Hydroxylase Enzymes in Rhodococcus rhodochrous DSM43269 for Specific Degradation of Different Classes of Steroids

Mycobacterium tuberculosis CYP125A1, a steroid C27 monooxygenase that detoxifies intracellularly generated cholest-4-en-3-one

Characterization of two steroid hydroxylases from different Streptomyces spp. and their ligand‐bound and ‐unbound crystal structures

Genetic and structural analyses of cytochrome P450 hydroxylases in sex hormone biosynthesis: Sequential origin and subsequent coevolution

Crystal Structure of CYP24A1, a Mitochondrial Cytochrome P450 Involved in Vitamin D Metabolism

Interaction of Apo-cytochrome b5 with Cytochromes P4503A4 and P45017A: Relevance of Heme Transfer Reactions

Antifungal Azoles: Structural Insights into Undesired Tight Binding to Cholesterol-Metabolizing CYP46A1

Orphan Nuclear Receptor RORα Regulates Enzymatic Metabolism of Cerebral 24S-Hydroxycholesterol through CYP39A1 Intronic Response Element Activation

Structure–function analysis for the hydroxylation of Δ4 C21‐steroids by the myxobacterial CYP260B1

Possible involvement of pregnane X receptor-enhanced CYP24 expression in drug-induced osteomalacia

Oxidation of 7-dehydrocholesterol and desmosterol by human cytochrome P450 46A1[S]

Ordered chimerogenesis applied to CYP2B P450 enzymes

Human steroid and oxysterol 7α‐hydroxylase CYP7B1: substrate specificity, azole binding and misfolding of clinically relevant mutants

Exploring the structural basis of substrate preferences in Baeyer-Villiger monooxygenases: insight from steroid monooxygenase

In Vitro and in Silico Analyses for Predicting Hepatic Cytochrome P450-Dependent Metabolic Potencies of Polychlorinated Biphenyls in the Baikal Seal

Structural Basis of Drug Binding to CYP46A1, an Enzyme That Controls Cholesterol Turnover in the Brain

Structural and Dynamic Basis of Human Cytochrome P450 7B1: A Survey of Substrate Selectivity and Major Active Site Access Channels

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