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Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport

Nature (London), 2019-05, Vol.569 (7754), p.141-145

2019

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Interaction of antidepressants with the serotonin and norepinephrine transporters: mutational studies of the S1 substrate binding pocket

The Journal of biological chemistry, 2012-12, Vol.287 (52), p.43694-43707

2012

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X-ray structures and mechanism of the human serotonin transporter

Nature (London), 2016-04, Vol.532 (7599), p.334-339

2016

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Molecular determinants for selective recognition of antidepressants in the human serotonin and norepinephrine transporters

Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (29), p.12137-12142

2011

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Structural basis for action by diverse antidepressants on biogenic amine transporters

Nature (London), 2013-11, Vol.503 (7474), p.141-145

2013

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Conformational dynamics of the human serotonin transporter during substrate and drug binding

Nature communications, 2019-04, Vol.10 (1), p.1687-1687, Article 1687

2019

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MiR-16 Targets the Serotonin Transporter: A New Facet for Adaptive Responses to Antidepressants

Science (American Association for the Advancement of Science), 2010-09, Vol.329 (5998), p.1537-1541

2010

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Cholesterol binding to a conserved site modulates the conformation, pharmacology, and transport kinetics of the human serotonin transporter

The Journal of biological chemistry, 2018-03, Vol.293 (10), p.3510-3523

2018

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Identification of the potassium-binding site in serotonin transporter

Proceedings of the National Academy of Sciences - PNAS, 2024-04, Vol.121 (18), p.e2319384121

2024

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Detergent-free purification and reconstitution of functional human serotonin transporter (SERT) using diisobutylene maleic acid (DIBMA) copolymer

Biochimica et biophysica acta. Biomembranes, 2021-07, Vol.1863 (7), p.183602-183602, Article 183602

2021

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Serotonin transporter variant drives preventable gastrointestinal abnormalities in development and function

The Journal of clinical investigation, 2016-06, Vol.126 (6), p.2221-2235

2016

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The mechanism of a high-affinity allosteric inhibitor of the serotonin transporter

Nature communications, 2020-03, Vol.11 (1), p.1491-12, Article 1491

2020

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Genetic variants in the serotonin transporter influence the efficacy of bupropion and nortriptyline in smoking cessation

Addiction (Abingdon, England), 2012-01, Vol.107 (1), p.178-187

2012

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Thermal Unfolding of the Human Serotonin Transporter: Differential Effect by Stabilizing and Destabilizing Mutations and Cholesterol on Thermodynamic and Kinetic Stability

Molecular pharmacology, 2022-02, Vol.101 (2), p.95-105

2022

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Potent and Selective Antisense Oligonucleotides Targeting Single-Nucleotide Polymorphisms in the Huntington Disease Gene / Allele-Specific Silencing of Mutant Huntingtin

Molecular therapy, 2011-12, Vol.19 (12), p.2178-2185

2011

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Unfaithful neurotransmitter transporters: focus on serotonin uptake and implications for antidepressant efficacy

Pharmacology & therapeutics (Oxford), 2009-01, Vol.121 (1), p.89-99

Daws, Lynette C

2009

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Conformational state interactions provide clues to the pharmacochaperone potential of serotonin transporter partial substrates

The Journal of biological chemistry, 2017-10, Vol.292 (40), p.16773-16786

2017

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Long noncoding RNA NONHSAG045500 regulates serotonin transporter to ameliorate depressive-like behavior via the cAMP-PKA-CREB signaling pathway in a model of perinatal depression

The journal of maternal-fetal & neonatal medicine, 2023-12, Vol.36 (1), p.2183468-2183468

2023

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Elucidation of Structural Elements for Selectivity across Monoamine Transporters: Novel 2‑[(Diphenylmethyl)sulfinyl]acetamide (Modafinil) Analogues

Journal of medicinal chemistry, 2014-02, Vol.57 (3), p.1000-1013

2014

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Huntingtin proteolysis releases non-polyQ fragments that cause toxicity through dynamin 1 dysregulation

The EMBO journal, 2015-09, Vol.34 (17), p.2255-2271

2015

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Ectopic expression of MmSERT, a mouse serotonin transporter gene, regulates salt tolerance and ABA sensitivity in apple and Arabidopsis

Plant physiology and biochemistry, 2023-04, Vol.197, p.107627-107627, Article 107627

2023

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Amphetamine actions at the serotonin transporter rely on the availability of phosphatidylinositol-4,5-bisphosphate

Proceedings of the National Academy of Sciences - PNAS, 2013-07, Vol.110 (28), p.11642-11647

2013

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Pharmacological or Genetic Inactivation of the Serotonin Transporter Improves Reversal Learning in Mice

Cerebral cortex (New York, N.Y. 1991), 2010-08, Vol.20 (8), p.1955-1963

2010

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Glycogen synthase kinase‐3ß supports serotonin transporter function and trafficking in a phosphorylation‐dependent manner

Journal of neurochemistry, 2021-02, Vol.156 (4), p.445-464

2021

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Role of the E3 ubiquitin ligase HRD1 in the regulation of serotonin transporter function

Biochemical and biophysical research communications, 2021-01, Vol.534, p.583-589

2021

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