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MicroRNA 7 Impairs Insulin Signaling and Regulates Aβ Levels through Posttranscriptional Regulation of the Insulin Receptor Substrate 2, Insulin Receptor, Insulin-Degrading Enzyme, and Liver X Receptor Pathway

Molecular and cellular biology, 2019-11, Vol.39 (22)

2019

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Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling

Neurobiology of aging, 2010-02, Vol.31 (2), p.224-243

2010

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Phosphorylation of IRS proteins, insulin action, and insulin resistance

American journal of physiology: endocrinology and metabolism, 2009-04, Vol.296 (4), p.E581-E591

2009

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The serine phosphorylations in the IRS-1 PIR domain abrogate IRS-1 and IR interaction

Proceedings of the National Academy of Sciences - PNAS, 2024-04, Vol.121 (17), p.e2401716121

2024

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Mitotic regulators and the SHP2-MAPK pathway promote IR endocytosis and feedback regulation of insulin signaling

Nature communications, 2019-04, Vol.10 (1), p.1473-1473, Article 1473

2019

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Central role of E3 ubiquitin ligase MG53 in insulin resistance and metabolic disorders

Nature (London), 2013-02, Vol.494 (7437), p.375-379

2013

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Leucine-973 is a crucial residue differentiating insulin and IGF-1 receptor signaling

The Journal of clinical investigation, 2023-02, Vol.133 (4)

2023

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Differential hepatic distribution of insulin receptor substrates causes selective insulin resistance in diabetes and obesity

Nature communications, 2016-10, Vol.7 (1), p.12977-12977, Article 12977

2016

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BRD7 improves glucose homeostasis independent of IRS proteins

Journal of endocrinology, 2023-09, Vol.258 (3)

2023

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Caveolin-2 palmitoylation turnover facilitates insulin receptor substrate-1-directed lipid metabolism by insulin receptor tyrosine kinase

Biochimica et biophysica acta. Molecular basis of disease, 2024-06, Vol.1870 (5), p.167173, Article 167173

2024

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Molecular mechanisms of metabolic regulation by insulin in Drosophila

Biochemical journal, 2010-01, Vol.425 (1), p.13-26

Teleman, Aurelio A

2010

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Intergenerational inheritance induced by a high-fat diet causes hyperphagia and reduced hypothalamic sensitivity to insulin and leptin in the second-generation of rats

Nutrition (Burbank, Los Angeles County, Calif.), 2024-04, Vol.120, p.112333-112333, Article 112333

2024

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Abundance of ruminal bacteria, epithelial gene expression, and systemic biomarkers of metabolism and inflammation are altered during the peripartal period in dairy cows

Journal of dairy science, 2015-12, Vol.98 (12), p.8940-8951

2015

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High Uric Acid Induces Insulin Resistance in Cardiomyocytes In Vitro and In Vivo

PloS one, 2016-02, Vol.11 (2), p.e0147737-e0147737

2016

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Involvement of Insulin Signaling Disturbances in Bisphenol A-Induced Alzheimer's Disease-like Neurotoxicity

Scientific reports, 2017-08, Vol.7 (1), p.7497-12, Article 7497

2017

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The P300 acetyltransferase inhibitor C646 promotes membrane translocation of insulin receptor protein substrate and interaction with the insulin receptor

The Journal of biological chemistry, 2022-03, Vol.298 (3), p.101621-101621, Article 101621

2022

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Regulatory Roles of MicroRNAs in Diabetes

International journal of molecular sciences, 2016-10, Vol.17 (10), p.1729-1729

2016

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Insulin Signaling Via Progesterone-Regulated Insulin Receptor Substrate 2 is Critical for Human Uterine Decidualization

Endocrinology (Philadelphia), 2020-01, Vol.161 (1), p.1

2020

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Cocoa flavonoids attenuate high glucose-induced insulin signalling blockade and modulate glucose uptake and production in human HepG2 cells

Food and chemical toxicology, 2014-02, Vol.64, p.10-19

2014

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The Glycolytic Enzyme, GPI, Is a Functionally Conserved Modifier of Dopaminergic Neurodegeneration in Parkinson’s Models

Cell metabolism, 2014-07, Vol.20 (1), p.145-157

2014

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Agriophyllum oligosaccharides ameliorate hepatic injury in type 2 diabetic db/db mice targeting INS-R/IRS-2/PI3K/AKT/PPAR-γ/Glut4 signal pathway

Journal of ethnopharmacology, 2020-07, Vol.257, p.112863-112863, Article 112863

2020

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Palmitate induces insulin resistance in human HepG2 hepatocytes by enhancing ubiquitination and proteasomal degradation of key insulin signaling molecules

Archives of biochemistry and biophysics, 2015-01, Vol.566, p.26-35

2015

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DPP4-inhibitor improves neuronal insulin receptor function, brain mitochondrial function and cognitive function in rats with insulin resistance induced by high-fat diet consumption

The European journal of neuroscience, 2013-03, Vol.37 (5), p.839-849

2013

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Central Resistin Overexposure Induces Insulin Resistance Through Toll-Like Receptor 4

Diabetes (New York, N.Y.), 2013-01, Vol.62 (1), p.102-114

2013

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Glucose Induces Mouse β-Cell Proliferation via IRS2, MTOR, and Cyclin D2 but Not the Insulin Receptor

Diabetes (New York, N.Y.), 2016-04, Vol.65 (4), p.981-995

2016

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MicroRNA 7 Impairs Insulin Signaling and Regulates Aβ Levels through Posttranscriptional Regulation of the Insulin Receptor Substrate 2, Insulin Receptor, Insulin-Degrading Enzyme, and Liver X Receptor Pathway

Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling

Phosphorylation of IRS proteins, insulin action, and insulin resistance

The serine phosphorylations in the IRS-1 PIR domain abrogate IRS-1 and IR interaction

Mitotic regulators and the SHP2-MAPK pathway promote IR endocytosis and feedback regulation of insulin signaling

Central role of E3 ubiquitin ligase MG53 in insulin resistance and metabolic disorders

Leucine-973 is a crucial residue differentiating insulin and IGF-1 receptor signaling

Differential hepatic distribution of insulin receptor substrates causes selective insulin resistance in diabetes and obesity

BRD7 improves glucose homeostasis independent of IRS proteins

Caveolin-2 palmitoylation turnover facilitates insulin receptor substrate-1-directed lipid metabolism by insulin receptor tyrosine kinase

Molecular mechanisms of metabolic regulation by insulin in Drosophila

Intergenerational inheritance induced by a high-fat diet causes hyperphagia and reduced hypothalamic sensitivity to insulin and leptin in the second-generation of rats

Abundance of ruminal bacteria, epithelial gene expression, and systemic biomarkers of metabolism and inflammation are altered during the peripartal period in dairy cows

High Uric Acid Induces Insulin Resistance in Cardiomyocytes In Vitro and In Vivo

Involvement of Insulin Signaling Disturbances in Bisphenol A-Induced Alzheimer's Disease-like Neurotoxicity

The P300 acetyltransferase inhibitor C646 promotes membrane translocation of insulin receptor protein substrate and interaction with the insulin receptor

Regulatory Roles of MicroRNAs in Diabetes

Insulin Signaling Via Progesterone-Regulated Insulin Receptor Substrate 2 is Critical for Human Uterine Decidualization

Cocoa flavonoids attenuate high glucose-induced insulin signalling blockade and modulate glucose uptake and production in human HepG2 cells

The Glycolytic Enzyme, GPI, Is a Functionally Conserved Modifier of Dopaminergic Neurodegeneration in Parkinson’s Models

Agriophyllum oligosaccharides ameliorate hepatic injury in type 2 diabetic db/db mice targeting INS-R/IRS-2/PI3K/AKT/PPAR-γ/Glut4 signal pathway

Palmitate induces insulin resistance in human HepG2 hepatocytes by enhancing ubiquitination and proteasomal degradation of key insulin signaling molecules

DPP4-inhibitor improves neuronal insulin receptor function, brain mitochondrial function and cognitive function in rats with insulin resistance induced by high-fat diet consumption

Central Resistin Overexposure Induces Insulin Resistance Through Toll-Like Receptor 4

Glucose Induces Mouse β-Cell Proliferation via IRS2, MTOR, and Cyclin D2 but Not the Insulin Receptor

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