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Transforming Fusions of FGFR and TACC Genes in Human Glioblastoma

Science (American Association for the Advancement of Science), 2012-09, Vol.337 (6099), p.1231-1235

2012

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FGF-dependent metabolic control of vascular development

Nature (London), 2017-05, Vol.545 (7653), p.224

2017

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In vitro and in vivo characterization of Recifercept, a soluble fibroblast growth factor receptor 3, as treatment for achondroplasia

PloS one, 2020-12, Vol.15 (12), p.e0244368-e0244368

2020

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Ensemble-Based Replica Exchange Alchemical Free Energy Methods: The Effect of Protein Mutations on Inhibitor Binding

Journal of chemical theory and computation, 2019-02, Vol.15 (2), p.1265-1277

2019

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Characterization of membrane protein interactions in plasma membrane derived vesicles with quantitative imaging Förster resonance energy transfer

Accounts of chemical research, 2015-08, Vol.48 (8), p.2262-2269

2015

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Sequential exposure to fibroblast growth factors (FGF) 2, 9 and 18 enhances hMSC chondrogenic differentiation

Osteoarthritis and cartilage, 2015-03, Vol.23 (3), p.443-453

2015

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Effect of Thanatophoric Dysplasia Type I Mutations on FGFR3 Dimerization

Biophysical journal, 2015-01, Vol.108 (2), p.272-278

2015

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Kinase Activity of Fibroblast Growth Factor Receptor 3 Regulates Activity of the Papillomavirus E2 Protein

Journal of virology, 2017-10, Vol.91 (20)

2017

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Amplification of FRS2 and Activation of FGFR/FRS2 Signaling Pathway in High-Grade Liposarcoma

Cancer research (Chicago, Ill.), 2013-02, Vol.73 (4), p.1298-1307

2013

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Antitumor Activity of Tasurgratinib as an Orally Available FGFR1-3 Inhibitor in Cholangiocarcinoma Models With FGFR2-fusion

Anticancer research, 2024-06, Vol.44 (6), p.2393

2024

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Biomarker-Oriented Therapy in Bladder and Renal Cancer

International journal of molecular sciences, 2021-03, Vol.22 (6), p.2832

2021

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Liquid Biopsy Analysis of FGFR3 and PIK3CA Hotspot Mutations for Disease Surveillance in Bladder Cancer

European urology, 2017-06, Vol.71 (6), p.961-969

2017

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Exploring mechanisms of FGF signalling through the lens of structural biology

Nature reviews. Molecular cell biology, 2013-03, Vol.14 (3), p.166

2013

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A novel tyrosine kinase inhibitor restores chondrocyte differentiation and promotes bone growth in a gain-of-function Fgfr3 mouse model

Human molecular genetics, 2012-02, Vol.21 (4), p.841-851

2012

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Futibatinib Is a Novel Irreversible FGFR 1-4 Inhibitor That Shows Selective Antitumor Activity against FGFR-Deregulated Tumors

Cancer research (Chicago, Ill.), 2020-11, Vol.80 (22), p.4986-4997

2020

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Selective over-expression of fibroblast growth factor receptors 1 and 4 in clinical prostate cancer

The Journal of pathology, 2007-09, Vol.213 (1), p.82-90

2007

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The Transition from Radial Glial to Intermediate Progenitor Cell Is Inhibited by FGF Signaling during Corticogenesis

The Journal of neuroscience, 2009-11, Vol.29 (46), p.14571-14580

2009

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Ligand-associated ERBB2/3 activation confers acquired resistance to FGFR inhibition in FGFR3-dependent cancer cells

Oncogene, 2015-04, Vol.34 (17), p.2167-2177

2015

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Pemigatinib: First Approval

Drugs (New York, N.Y.), 2020-06, Vol.80 (9), p.923-929

Hoy, Sheridan M.

2020

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Genomic aberrations in the FGFR pathway: opportunities for targeted therapies in solid tumors

Annals of oncology, 2014-03, Vol.25 (3), p.552-563

2014

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Genetically confirmed thanatophoric dysplasia with fibroblast growth factor receptor 3 mutation

Experimental and molecular pathology, 2017-04, Vol.102 (2), p.290-295

2017

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Crosstalk between KIT and FGFR3 Promotes Gastrointestinal Stromal Tumor Cell Growth and Drug Resistance

Cancer research (Chicago, Ill.), 2015-03, Vol.75 (5), p.880-891

2015

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Pathogenic Cysteine Removal Mutations in FGFR Extracellular Domains Stabilize Receptor Dimers and Perturb the TM Dimer Structure

Journal of molecular biology, 2016-10, Vol.428 (20), p.3903-3910

2016

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Protein arginine methyltransferase 5 is essential for growth of lung cancer cells

Biochemical journal, 2012-09, Vol.446 (2), p.235-241

2012

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Increased FGFR3 is involved in T-2 toxin-induced lesions of hypertrophic cartilage associated with endemic osteoarthritis

Human & experimental toxicology, 2023-01, Vol.42, p.9603271231219480-9603271231219480

2023

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Transforming Fusions of FGFR and TACC Genes in Human Glioblastoma

FGF-dependent metabolic control of vascular development

In vitro and in vivo characterization of Recifercept, a soluble fibroblast growth factor receptor 3, as treatment for achondroplasia

Ensemble-Based Replica Exchange Alchemical Free Energy Methods: The Effect of Protein Mutations on Inhibitor Binding

Characterization of membrane protein interactions in plasma membrane derived vesicles with quantitative imaging Förster resonance energy transfer

Sequential exposure to fibroblast growth factors (FGF) 2, 9 and 18 enhances hMSC chondrogenic differentiation

Effect of Thanatophoric Dysplasia Type I Mutations on FGFR3 Dimerization

Kinase Activity of Fibroblast Growth Factor Receptor 3 Regulates Activity of the Papillomavirus E2 Protein

Amplification of FRS2 and Activation of FGFR/FRS2 Signaling Pathway in High-Grade Liposarcoma

Antitumor Activity of Tasurgratinib as an Orally Available FGFR1-3 Inhibitor in Cholangiocarcinoma Models With FGFR2-fusion

Biomarker-Oriented Therapy in Bladder and Renal Cancer

Liquid Biopsy Analysis of FGFR3 and PIK3CA Hotspot Mutations for Disease Surveillance in Bladder Cancer

Exploring mechanisms of FGF signalling through the lens of structural biology

A novel tyrosine kinase inhibitor restores chondrocyte differentiation and promotes bone growth in a gain-of-function Fgfr3 mouse model

Futibatinib Is a Novel Irreversible FGFR 1-4 Inhibitor That Shows Selective Antitumor Activity against FGFR-Deregulated Tumors

Selective over-expression of fibroblast growth factor receptors 1 and 4 in clinical prostate cancer

The Transition from Radial Glial to Intermediate Progenitor Cell Is Inhibited by FGF Signaling during Corticogenesis

Ligand-associated ERBB2/3 activation confers acquired resistance to FGFR inhibition in FGFR3-dependent cancer cells

Pemigatinib: First Approval

Genomic aberrations in the FGFR pathway: opportunities for targeted therapies in solid tumors

Genetically confirmed thanatophoric dysplasia with fibroblast growth factor receptor 3 mutation

Crosstalk between KIT and FGFR3 Promotes Gastrointestinal Stromal Tumor Cell Growth and Drug Resistance

Pathogenic Cysteine Removal Mutations in FGFR Extracellular Domains Stabilize Receptor Dimers and Perturb the TM Dimer Structure

Protein arginine methyltransferase 5 is essential for growth of lung cancer cells

Increased FGFR3 is involved in T-2 toxin-induced lesions of hypertrophic cartilage associated with endemic osteoarthritis

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