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1,1,1-Trichloropropene-2,3-oxide: an alternate mechanism for its inhibition of cytochrome P-450

Research communications in chemical pathology and pharmacology, 1982-01, Vol.35 (1), p.111

1982

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1,1,2,2-TETRACHLOROETHANE-INDUCED EARLY DECREASE OF DOLICHOL LEVELS IN RAT LIVER MICROSOMES AND GOLGI APPARATUS

Journal of Toxicology and Environmental Health, Part A, 1998-05, Vol.54 (2), p.133-144

1998

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1-[1-(2-Benzo[b]thiopheneyl)cyclohexyl]piperidine Hydrochloride (BTCP) Yields Two Active Primary Metabolites in Vitro: Synthesis, Identification from Rat Liver Microsome Extracts, and Affinity for the Neuronal Dopamine Transporter

Journal of medicinal chemistry, 1997-12, Vol.40 (25), p.4019-4025

1997

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1, 1, 2-TRICHLOROETHANE: EVIDENCE OF GENOTOXICITY FROM SHORT-TERM TESTS

Japanese Journal of Cancer Research GANN, 1986, Vol.77(6), pp.532-539

1986

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1,1-Bisphosphonate Squalene Synthase Inhibitors: Interplay Between the Isoprenoid Subunit and the Diphosphate Surrogate

Journal of medicinal chemistry, 1995-07, Vol.38 (14), p.2596-2605

1995

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1,1-Dichloroethylene inhibition of liver microsomal calcium pump in vitro

Archives of biochemistry and biophysics, 1982-10, Vol.218 (1), p.26-30

1982

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1,1-Diheterocyclic Ethylenes Derived from Quinaldine and Carbazole as New Tubulin-Polymerization Inhibitors: Synthesis, Metabolism, and Biological Evaluation

Journal of medicinal chemistry, 2019-02, Vol.62 (4), p.1902-1916

2019

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1-[(1-Methyl-1H-imidazol-2-yl)methyl]-4-phenylpiperidines as mGluR2 Positive Allosteric Modulators for the Treatment of Psychosis

Journal of medicinal chemistry, 2011-03, Vol.54 (6), p.1724-1739

2011

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1-(2-(2,2,2-trifluoroethoxy)ethyl-1H-pyrazolo[4,3-d]pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors

Bioorganic & medicinal chemistry letters, 2010-05, Vol.20 (10), p.3125-3128

2010

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1,2,4-triazol-3-yl-thiopropyl-tetrahydrobenzazepines: a series of potent and selective dopamine D(3) receptor antagonists

Journal of medicinal chemistry, 2007-10, Vol.50 (21), p.5076

2007

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[1,2,4]Triazolo[1,5‑a]pyrimidine Phosphodiesterase 2A Inhibitors: Structure and Free-Energy Perturbation-Guided Exploration

Journal of medicinal chemistry, 2020-11, Vol.63 (21), p.12887-12910

2020

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1,2,4-Triazolsulfone: A novel isosteric replacement of acylsulfonamides in the context of Na V 1.7 inhibition

Bioorganic & medicinal chemistry letters, 2018-06, Vol.28 (11), p.2103-2108

2018

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1,2-Benzisoxazole Phosphorodiamidates as Novel Anticancer Prodrugs Requiring Bioreductive Activation

Journal of medicinal chemistry, 2003-12, Vol.46 (25), p.5428-5436

2003

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1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) modulates rat liver microsomal cyclophosphamide and ifosphamide activation by suppressing cytochrome P450 2C11 messenger RNA levels

Drug metabolism and disposition, 1994-09, Vol.22 (5), p.673

1994

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The 1,2-dichloroethylenes: Their metabolism by hepatic cytochrome P-450 in vitro

Biochemical pharmacology, 1982-06, Vol.31 (11), p.2093-2102

1982

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1,2-naphthalene oxide as an intermediate in the microsomal hydroxylation of naphthalene

Biochemistry (Easton), 1970-01, Vol.9 (1), p.147-156

1970

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1,25-Dihydroxyvitamin D Synthesis in Rat Liver Microsomes

Hormone and metabolic research, 1995-10, Vol.27 (10), p.461-464

1995

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1,3,5-Trialkyl-2,4,6-triiodobenzenes: Novel X-ray Contrast Agents for Gastrointestinal Imaging

Journal of medicinal chemistry, 2000-05, Vol.43 (10), p.1940-1948

2000

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1,3,5-Trisubstituted Pyrazoles as Potent Negative Allosteric Modulators of the mGlu 2/3 Receptors

ChemMedChem, 2017-06, Vol.12 (12), p.905-912

2017

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1-(3-Aryloxyaryl)benzimidazole sulfones are liver X receptor agonists

Bioorganic & medicinal chemistry letters, 2010-01, Vol.20 (2), p.526-530

2010

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1,3-Butadiene: Linking Metabolism, Dosimetry, and Mutation Induction

Environmental health perspectives, 1994-11, Vol.102 (suppl 9), p.87-94

1994

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1,3-Disubstituted Ureas Functionalized with Ether Groups are Potent Inhibitors of the Soluble Epoxide Hydrolase with Improved Pharmacokinetic Properties

Journal of medicinal chemistry, 2007-10, Vol.50 (21), p.5217-5226

2007

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1,4,9-Triazaspiro[5.5]undecan-2-one Derivatives as Potent and Selective METTL3 Inhibitors

Journal of medicinal chemistry, 2021-09, Vol.64 (17), p.12738-12760

2021

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1,4-Diazepane compounds as potent and selective CB2 agonists: Optimization of metabolic stability

Bioorganic & medicinal chemistry letters, 2011-04, Vol.21 (7), p.2011-2016

2011

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1,1,1-Trichloropropene-2,3-oxide: an alternate mechanism for its inhibition of cytochrome P-450

1,1,2,2-TETRACHLOROETHANE-INDUCED EARLY DECREASE OF DOLICHOL LEVELS IN RAT LIVER MICROSOMES AND GOLGI APPARATUS

1-[1-(2-Benzo[b]thiopheneyl)cyclohexyl]piperidine Hydrochloride (BTCP) Yields Two Active Primary Metabolites in Vitro: Synthesis, Identification from Rat Liver Microsome Extracts, and Affinity for the Neuronal Dopamine Transporter

1, 1, 2-TRICHLOROETHANE: EVIDENCE OF GENOTOXICITY FROM SHORT-TERM TESTS

1,1-Bisphosphonate Squalene Synthase Inhibitors: Interplay Between the Isoprenoid Subunit and the Diphosphate Surrogate

1,1-Dichloroethylene inhibition of liver microsomal calcium pump in vitro

1,1-Diheterocyclic Ethylenes Derived from Quinaldine and Carbazole as New Tubulin-Polymerization Inhibitors: Synthesis, Metabolism, and Biological Evaluation

1-[(1-Methyl-1H-imidazol-2-yl)methyl]-4-phenylpiperidines as mGluR2 Positive Allosteric Modulators for the Treatment of Psychosis

1-[2-(1-Cyclobutylpiperidin-4-yloxy)-6,7-dihydro-4H-thiazolo[5,4-c]pyridin-5-yl]propan-1-one: a Histamine H 3 Receptor Inverse Agonist with Efficacy in Animal Models of Cognition

1-(2-(2,2,2-trifluoroethoxy)ethyl-1H-pyrazolo[4,3-d]pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors

1,2,4-triazol-3-yl-thiopropyl-tetrahydrobenzazepines: a series of potent and selective dopamine D(3) receptor antagonists

[1,2,4]Triazolo[1,5‑a]pyrimidine Phosphodiesterase 2A Inhibitors: Structure and Free-Energy Perturbation-Guided Exploration

1,2,4-Triazolsulfone: A novel isosteric replacement of acylsulfonamides in the context of Na V 1.7 inhibition

1,2-Benzisoxazole Phosphorodiamidates as Novel Anticancer Prodrugs Requiring Bioreductive Activation

1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) modulates rat liver microsomal cyclophosphamide and ifosphamide activation by suppressing cytochrome P450 2C11 messenger RNA levels

The 1,2-dichloroethylenes: Their metabolism by hepatic cytochrome P-450 in vitro

1,2-naphthalene oxide as an intermediate in the microsomal hydroxylation of naphthalene

1,25-Dihydroxyvitamin D Synthesis in Rat Liver Microsomes

1,3,5-Trialkyl-2,4,6-triiodobenzenes: Novel X-ray Contrast Agents for Gastrointestinal Imaging

1,3,5-Trisubstituted Pyrazoles as Potent Negative Allosteric Modulators of the mGlu 2/3 Receptors

1-(3-Aryloxyaryl)benzimidazole sulfones are liver X receptor agonists

1,3-Butadiene: Linking Metabolism, Dosimetry, and Mutation Induction

1,3-Disubstituted Ureas Functionalized with Ether Groups are Potent Inhibitors of the Soluble Epoxide Hydrolase with Improved Pharmacokinetic Properties

1,4,9-Triazaspiro[5.5]undecan-2-one Derivatives as Potent and Selective METTL3 Inhibitors

1,4-Diazepane compounds as potent and selective CB2 agonists: Optimization of metabolic stability

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