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Structural identification of a hotspot on CFTR for potentiation

Science (American Association for the Advancement of Science), 2019-06, Vol.364 (6446), p.1184-1188

2019

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SEP-363856, a Novel Psychotropic Agent with a Unique, Non-D 2 Receptor Mechanism of Action

The Journal of pharmacology and experimental therapeutics, 2019-10, Vol.371 (1), p.1

2019

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Omarigliptin (MK-3102): A Novel Long-Acting DPP‑4 Inhibitor for Once-Weekly Treatment of Type 2 Diabetes

Journal of medicinal chemistry, 2014-04, Vol.57 (8), p.3205-3212

2014

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Regulation of seed germination and seedling growth by chemical signals from burning vegetation

Annual review of plant biology, 2012-01, Vol.63 (1), p.107-130

2012

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A facile one-pot green synthesis and antibacterial activity of 2-amino-4H-pyrans and 2-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromenes

European journal of medicinal chemistry, 2009-09, Vol.44 (9), p.3805-3809

2009

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Discovery of Novel Dihydrothiopyrano[4,3‑d]pyrimidine Derivatives as Potent HIV‑1 NNRTIs with Significantly Reduced hERG Inhibitory Activity and Improved Resistance Profiles

Journal of medicinal chemistry, 2021-09, Vol.64 (18), p.13658-13675

2021

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Metabolic and evolutionary origin of actin-binding polyketides from diverse organisms

Nature chemical biology, 2015-09, Vol.11 (9), p.705

2015

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Salinomycin as a potent anticancer stem cell agent: State of the art and future directions

Medicinal research reviews, 2022-05, Vol.42 (3), p.1037-1063

2022

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A Metal-Free Path to 2-Iodo-3-alkyl-1-arylbut-2-en-1-ones and Their Application to the Domino Synthesis of Functionalized 2 H -Pyran-2-ones

Journal of organic chemistry, 2022-03, Vol.87 (5), p.2222-2240

2022

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Real-Time Tracking and In Vivo Visualization of β‑Galactosidase Activity in Colorectal Tumor with a Ratiometric Near-Infrared Fluorescent Probe

Journal of the American Chemical Society, 2016-04, Vol.138 (16), p.5334-5340

2016

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Synthesis and Bioactivities of Marine Pyran-Isoindolone Derivatives as Potential Antithrombotic Agents

Marine drugs, 2021-04, Vol.19 (4), p.218

2021

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Enantioselective Synthesis of Thailanstatin A Methyl Ester and Evaluation of in Vitro Splicing Inhibition

Journal of organic chemistry, 2018-05, Vol.83 (9), p.5187-5198

2018

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Meglumine: A Novel and Efficient Catalyst for One-Pot, Three-Component Combinatorial Synthesis of Functionalized 2‑Amino‑4H‑pyrans

ACS combinatorial science, 2013-11, Vol.15 (11), p.557-563

2013

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Total Syntheses of Thailanstatins A–C, Spliceostatin D, and Analogues Thereof. Stereodivergent Synthesis of Tetrasubstituted Dihydro- and Tetrahydropyrans and Design, Synthesis, Biological Evaluation, and Discovery of Potent Antitumor Agents

Journal of the American Chemical Society, 2018-07, Vol.140 (26), p.8303-8320

2018

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Identification and Persistence of 5,6-Dihydro-2 H -pyran-3-carboxaldehyde in Aged Aqueous Acrolein Media

Journal of agricultural and food chemistry, 2021-02, Vol.69 (7), p.2069-2075

2021

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Synthesis, Antimicrobial Evaluation, DFT, and Molecular Docking Studies of Pyrano [4,3‐b] Pyranone and Pyrano[2,3‐b]Pyridinone Systems

Chemistry & biodiversity, 2024-05, Vol.21 (5), p.e202400243-n/a

2024

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Salinomycin kills cancer stem cells by sequestering iron in lysosomes

Nature chemistry, 2017-10, Vol.9 (10), p.1025

2017

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Cytotoxic Spliceostatins from Burkholderia sp. and Their Semisynthetic Analogues

Journal of natural products (Washington, D.C.), 2014-08, Vol.77 (8), p.1864-1870

2014

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Salinomycin as a drug for targeting human cancer stem cells

BioMed research international, 2012-01, Vol.2012, p.950658

2012

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Salinomycin-loaded PLA nanoparticles: drug quantification by GPC and wave voltammetry and biological studies on osteosarcoma cancer stem cells

Analytical and bioanalytical chemistry, 2020-07, Vol.412 (19), p.4681-4690

2020

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An environmentally benign protocol for aqueous synthesis of tetrahydrobenzo[b]pyrans catalyzed by cost-effective ionic liquid

International journal of molecular sciences, 2014-04, Vol.15 (4), p.6897-6909

2014

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Sodium alginate: An efficient biopolymeric catalyst for green synthesis of 2-amino-4H-pyran derivatives

International journal of biological macromolecules, 2016-06, Vol.87, p.172-179

2016

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Salinomycin: a novel anti-cancer agent with known anti-coccidial activities

Current medicinal chemistry, 2013-11, Vol.20 (33), p.4095

2013

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Potential Uses of Olive Oil Secoiridoids for the Prevention and Treatment of Cancer: A Narrative Review of Preclinical Studies

International journal of molecular sciences, 2021-01, Vol.22 (3), p.1234

2021

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Strategies for the construction of tetrahydropyran rings in the synthesis of natural products

Organic & biomolecular chemistry, 2014-06, Vol.12 (21), p.3323-3335

2014

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