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Identification and structure–activity relationships of substituted pyridones as inhibitors of Pim-1 kinase

Bioorganic & medicinal chemistry letters, 2007-03, Vol.17 (6), p.1679-1683

2007

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Indole: A privileged scaffold for the design of anti-cancer agents

European journal of medicinal chemistry, 2019-12, Vol.183, p.111691-111691, Article 111691

2019

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Metal-organic framework MOF-801/PIM-1 mixed-matrix membranes for enhanced CO2/N2 separation performance

Separation and purification technology, 2020-11, Vol.250, p.117198, Article 117198

2020

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Cell-permeable dual inhibitors of protein kinases CK2 and PIM-1: structural features and pharmacological potential

Cellular and molecular life sciences : CMLS, 2014-08, Vol.71 (16), p.3173-3185

2014

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Pim kinases in cancer: Diagnostic, prognostic and treatment opportunities

Biochemical pharmacology, 2013-03, Vol.85 (5), p.629-643

2013

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PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers

Haematologica (Roma), 2010-06, Vol.95 (6), p.1004-1015

2010

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New Azo-DMOF‑1 MOF as a Photoresponsive Low-Energy CO2 Adsorbent and Its Exceptional CO2/N2 Separation Performance in Mixed Matrix Membranes

ACS applied materials & interfaces, 2018-10, Vol.10 (40), p.34291-34301

2018

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Molecular design and fabrication of PIM-1/polyphosphazene blend membranes with high performance for CO2/N2 separation

Journal of membrane science, 2021-12, Vol.640 (C), p.119764, Article 119764

2021

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High gas permeance in CO2-selective thin film composite membranes from bis(phenyl)fluorene-containing blends with PIM-1

Journal of membrane science, 2024-04, Vol.699, p.122652, Article 122652

2024

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Targeting PIM Kinase with PD1 Inhibition Improves Immunotherapeutic Antitumor T-cell Response

Clinical cancer research, 2019-02, Vol.25 (3), p.1036-1049

2019

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The Pim kinase inhibitor SGI-1776 decreases cell surface expression of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) and drug transport by Pim-1-dependent and -independent mechanisms

Biochemical pharmacology, 2013-02, Vol.85 (4), p.514-524

2013

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Eco-friendly synthesis of novel cyanopyridine derivatives and their anticancer and PIM-1 kinase inhibitory activities

European journal of medicinal chemistry, 2017-07, Vol.134, p.357-365

2017

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Human Cardiac Progenitor Cells Engineered With Pim-I Kinase Enhance Myocardial Repair

Journal of the American College of Cardiology, 2012-10, Vol.60 (14), p.1278-1287

2012

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Direct phosphorylation and stabilization of HIF-1α by PIM1 kinase drives angiogenesis in solid tumors

Oncogene, 2021-08, Vol.40 (32), p.5142-5152

2021

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A systematic review on active sites and functions of PIM-1 protein

Human cell : official journal of Human Cell Research Society, 2022-03, Vol.35 (2), p.427-440

2022

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MicroRNA‐124‐3p regulates cell proliferation, invasion, apoptosis, and bioenergetics by targeting PIM1 in astrocytoma

Cancer science, 2016-07, Vol.107 (7), p.899-907

2016

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PIM kinase (and Akt) biology and signaling in tumors

Pharmacology & therapeutics (Oxford), 2015-07, Vol.151, p.41-49

2015

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Pim-1L Protects Cell Surface-Resident ABCA1 From Lysosomal Degradation in Hepatocytes and Thereby Regulates Plasma High-Density Lipoprotein Level

Arteriosclerosis, thrombosis, and vascular biology, 2016-12, Vol.36 (12), p.2304

2016

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Combined BRAF and PIM1 inhibitory therapy for papillary thyroid carcinoma based on BRAFV600E regulation of PIM1: Synergistic effect and metabolic mechanisms

Neoplasia (New York, N.Y.), 2024-06, Vol.52, p.100996-100996, Article 100996

2024

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Recent progress in PIM-1 based membranes for sustainable CO2 separations: Polymer structure manipulation and mixed matrix membrane design

Separation and purification technology, 2022-02, Vol.284, p.120277, Article 120277

2022

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PIM1 Kinase Phosphorylates the Human Transcription Factor FOXP3 at Serine 422 to Negatively Regulate Its Activity under Inflammation

The Journal of biological chemistry, 2014-09, Vol.289 (39), p.26872-26881

2014

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Imparting aromaticity to 2-pyridone derivatives by O -alkylation resulted in new competitive and non-competitive PIM-1 kinase inhibitors with caspase-activated apoptosis

Journal of enzyme inhibition and medicinal chemistry, 2024-12, Vol.39 (1), p.2304044-2304044

2024

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Synthesis and biological evaluation of quinoline derivatives as potential anti-prostate cancer agents and Pim-1 kinase inhibitors

Bioorganic & medicinal chemistry, 2016-04, Vol.24 (8), p.1889-1897

2016

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Long Noncoding RNA KCNQ1OT1 Confers Gliomas Resistance to Temozolomide and Enhances Cell Growth by Retrieving PIM1 From miR-761

Cellular and molecular neurobiology, 2022-04, Vol.42 (3), p.695-708

2022

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Identification and structure–activity relationships of substituted pyridones as inhibitors of Pim-1 kinase

Indole: A privileged scaffold for the design of anti-cancer agents

Metal-organic framework MOF-801/PIM-1 mixed-matrix membranes for enhanced CO2/N2 separation performance

Cell-permeable dual inhibitors of protein kinases CK2 and PIM-1: structural features and pharmacological potential

Pim kinases in cancer: Diagnostic, prognostic and treatment opportunities

PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers

New Azo-DMOF‑1 MOF as a Photoresponsive Low-Energy CO2 Adsorbent and Its Exceptional CO2/N2 Separation Performance in Mixed Matrix Membranes

Molecular design and fabrication of PIM-1/polyphosphazene blend membranes with high performance for CO2/N2 separation

High gas permeance in CO2-selective thin film composite membranes from bis(phenyl)fluorene-containing blends with PIM-1

Targeting PIM Kinase with PD1 Inhibition Improves Immunotherapeutic Antitumor T-cell Response

The Pim kinase inhibitor SGI-1776 decreases cell surface expression of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) and drug transport by Pim-1-dependent and -independent mechanisms

Eco-friendly synthesis of novel cyanopyridine derivatives and their anticancer and PIM-1 kinase inhibitory activities

Human Cardiac Progenitor Cells Engineered With Pim-I Kinase Enhance Myocardial Repair

Direct phosphorylation and stabilization of HIF-1α by PIM1 kinase drives angiogenesis in solid tumors

A systematic review on active sites and functions of PIM-1 protein

MicroRNA‐124‐3p regulates cell proliferation, invasion, apoptosis, and bioenergetics by targeting PIM1 in astrocytoma

PIM kinase (and Akt) biology and signaling in tumors

Pim-1L Protects Cell Surface-Resident ABCA1 From Lysosomal Degradation in Hepatocytes and Thereby Regulates Plasma High-Density Lipoprotein Level

Combined BRAF and PIM1 inhibitory therapy for papillary thyroid carcinoma based on BRAFV600E regulation of PIM1: Synergistic effect and metabolic mechanisms

Recent progress in PIM-1 based membranes for sustainable CO2 separations: Polymer structure manipulation and mixed matrix membrane design

PIM1 Kinase Phosphorylates the Human Transcription Factor FOXP3 at Serine 422 to Negatively Regulate Its Activity under Inflammation

Imparting aromaticity to 2-pyridone derivatives by O -alkylation resulted in new competitive and non-competitive PIM-1 kinase inhibitors with caspase-activated apoptosis

PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer

Synthesis and biological evaluation of quinoline derivatives as potential anti-prostate cancer agents and Pim-1 kinase inhibitors

Long Noncoding RNA KCNQ1OT1 Confers Gliomas Resistance to Temozolomide and Enhances Cell Growth by Retrieving PIM1 From miR-761

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