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Ubiquitin-proteasome dependent regulation of Profilin2 (Pfn2) by a cellular inhibitor of apoptotic protein 1 (cIAP1)

Biochemical and biophysical research communications, 2018-11, Vol.506 (3), p.423-428

2018

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Profilin1 biology and its mutation, actin(g) in disease

Cellular and molecular life sciences : CMLS, 2017-03, Vol.74 (6), p.967-981

2017

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The Loss of Profilin 1 Causes Early Onset Paget's Disease of Bone

Journal of bone and mineral research, 2020-08, Vol.35 (8), p.1387-1398

2020

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Genetic Screening of ZNF687 and PFN1 in a Paget’s Disease of Bone Cohort Indicates an Important Role for the Nuclear Localization Signal of ZNF687

Calcified tissue international, 2023-11, Vol.113 (5), p.552-557

2023

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Detergent‐insoluble inclusion constitutes the first pathology in PFN1 transgenic rats

Journal of neurochemistry, 2021-05, Vol.157 (4), p.1244-1252

2021

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Association of PFN1 Gene Polymorphisms with Bone Mineral Density, Bone Turnover Markers, and Osteoporotic Fractures in Chinese Population

Calcified tissue international, 2023-08, Vol.113 (2), p.207-215

2023

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A novel lncRNA promotes myogenesis of bovine skeletal muscle satellite cells via PFN1-RhoA/Rac1

Journal of cellular and molecular medicine, 2021-05, Vol.25 (13), p.5988-6005

2021

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HLA-F-AS1/miR-330-3p/PFN1 axis promotes colorectal cancer progression

Life sciences (1973), 2020-08, Vol.254, p.117180-9, Article 117180

2020

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Mutations in Profilin 1 Cause Early‐Onset Paget's Disease of Bone With Giant Cell Tumors

Journal of bone and mineral research, 2021-06, Vol.36 (6), p.1088-1103

2021

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LncRNA PEG11as aggravates cerebral ischemia/reperfusion injury after ischemic stroke through miR-342-5p/PFN1 axis

Life sciences (1973), 2023-01, Vol.313, p.121276-121276, Article 121276

2023

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Identification of a novel lactylation-related gene signature predicts the prognosis of multiple myeloma and experiment verification

Scientific reports, 2024-07, Vol.14 (1), p.15142-12, Article 15142

2024

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Mutation analysis of PFN1 in familial amyotrophic lateral sclerosis patients

Neurobiology of aging, 2013-04, Vol.34 (4), p.1311.e1-1311.e2

2013

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Knockdown of lncRNA HCP5 Suppresses the Progression of Colorectal Cancer by miR-299-3p/PFN1/AKT Axis

Cancer management and research, 2020-01, Vol.12, p.4747-4758

2020

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The Neglected Genes of ALS: Cytoskeletal Dynamics Impact Synaptic Degeneration in ALS

Frontiers in cellular neuroscience, 2020-11, Vol.14, p.594975-594975

2020

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Long noncoding RNA RMRP ameliorates doxorubicin-induced apoptosis by interacting with PFN1 in a P53-Dependent manner

Molecular and cellular probes, 2023-12, Vol.72, p.101937-101937, Article 101937

2023

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Mutant Profilin1 Aggregation in Amyotrophic Lateral Sclerosis: An in Vivo Biochemical Analysis

Basic and clinical neuroscience, 2021-03, Vol.12 (2), p.213-222

2021

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Novel variant c.92T > G (p.Val31Gly) in the PFN1 gene (ALS18) responsible for a specific phenotype in a large Bulgarian amyotrophic lateral sclerosis pedigree

Frontiers in neurology, 2023-02, Vol.14, p.1094234-1094234

2023

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Profilin1 Promotes Renal Tubular Epithelial Cell Apoptosis in Diabetic Nephropathy Through the Hedgehog Signaling Pathway

Diabetes, metabolic syndrome and obesity, 2023-01, Vol.16, p.1731-1743

2023

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Disruption of profilin1 function suppresses developmental and pathological retinal neovascularization

The Journal of biological chemistry, 2020-07, Vol.295 (28), p.9618-9629

2020

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Mutation of PFN1 Gene in an Early Onset, Polyostotic Paget-like Disease

The journal of clinical endocrinology and metabolism, 2020-08, Vol.105 (8), p.2553-2565

2020

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Transcriptome analysis of the cerebral cortex of acrylamide-exposed wild-type and IL-1β-knockout mice

Archives of toxicology, 2024-01, Vol.98 (1), p.181-205

2024

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Detergent-insoluble PFN1 inoculation expedites disease onset and progression in PFN1 transgenic rats

Frontiers in neuroscience, 2023-09, Vol.17, p.1279259-1279259

2023

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ALS-causing profilin-1-mutant forms a non-native helical structure in membrane environments

Biochimica et biophysica acta. Biomembranes, 2017-11, Vol.1859 (11), p.2161-2170

2017

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The identification of high-performing antibodies for Profilin-1 for use in Western blot, immunoprecipitation and immunofluorescence [version 1; peer review: 1 approved, 2 approved with reservations]

F1000 research, 2023, Vol.12, p.348-348

2023

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ALS-causing mutations in profilin-1 alter its conformational dynamics: A computational approach to explain propensity for aggregation

Scientific reports, 2018-08, Vol.8 (1), p.13102-10, Article 13102

2018

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Ubiquitin-proteasome dependent regulation of Profilin2 (Pfn2) by a cellular inhibitor of apoptotic protein 1 (cIAP1)

Profilin1 biology and its mutation, actin(g) in disease

The Loss of Profilin 1 Causes Early Onset Paget's Disease of Bone

Genetic Screening of ZNF687 and PFN1 in a Paget’s Disease of Bone Cohort Indicates an Important Role for the Nuclear Localization Signal of ZNF687

Detergent‐insoluble inclusion constitutes the first pathology in PFN1 transgenic rats

Association of PFN1 Gene Polymorphisms with Bone Mineral Density, Bone Turnover Markers, and Osteoporotic Fractures in Chinese Population

A novel lncRNA promotes myogenesis of bovine skeletal muscle satellite cells via PFN1-RhoA/Rac1

HLA-F-AS1/miR-330-3p/PFN1 axis promotes colorectal cancer progression

Mutations in Profilin 1 Cause Early‐Onset Paget's Disease of Bone With Giant Cell Tumors

LncRNA PEG11as aggravates cerebral ischemia/reperfusion injury after ischemic stroke through miR-342-5p/PFN1 axis

Identification of a novel lactylation-related gene signature predicts the prognosis of multiple myeloma and experiment verification

Mutation analysis of PFN1 in familial amyotrophic lateral sclerosis patients

Knockdown of lncRNA HCP5 Suppresses the Progression of Colorectal Cancer by miR-299-3p/PFN1/AKT Axis

The Neglected Genes of ALS: Cytoskeletal Dynamics Impact Synaptic Degeneration in ALS

Long noncoding RNA RMRP ameliorates doxorubicin-induced apoptosis by interacting with PFN1 in a P53-Dependent manner

Mutant Profilin1 Aggregation in Amyotrophic Lateral Sclerosis: An in Vivo Biochemical Analysis

Novel variant c.92T > G (p.Val31Gly) in the PFN1 gene (ALS18) responsible for a specific phenotype in a large Bulgarian amyotrophic lateral sclerosis pedigree

Profilin1 Promotes Renal Tubular Epithelial Cell Apoptosis in Diabetic Nephropathy Through the Hedgehog Signaling Pathway

Disruption of profilin1 function suppresses developmental and pathological retinal neovascularization

Mutation of PFN1 Gene in an Early Onset, Polyostotic Paget-like Disease

Transcriptome analysis of the cerebral cortex of acrylamide-exposed wild-type and IL-1β-knockout mice

Detergent-insoluble PFN1 inoculation expedites disease onset and progression in PFN1 transgenic rats

ALS-causing profilin-1-mutant forms a non-native helical structure in membrane environments

The identification of high-performing antibodies for Profilin-1 for use in Western blot, immunoprecipitation and immunofluorescence [version 1; peer review: 1 approved, 2 approved with reservations]

ALS-causing mutations in profilin-1 alter its conformational dynamics: A computational approach to explain propensity for aggregation

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