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Structures and target recognition modes of PDZ domains: recurring themes and emerging pictures

Biochemical journal, 2013-10, Vol.455 (1), p.1-14

2013

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Tight junction formation by a claudin mutant lacking the COOH‐terminal PDZ domain‐binding motif

Annals of the New York Academy of Sciences, 2022-10, Vol.1516 (1), p.85-94

2022

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Lock and chop: A novel method for the generation of a PICK1 PDZ domain and piperidine‐based inhibitor co‐crystal structure

Protein science, 2018-03, Vol.27 (3), p.672-680

2018

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The PDZ protein SCRIB regulates sodium/iodide symporter (NIS) expression at the basolateral plasma membrane

The FASEB journal, 2021-08, Vol.35 (8), p.n/a

2021

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Emerging Themes in PDZ Domain Signaling: Structure, Function, and Inhibition

International review of cell and molecular biology, 2019-01, Vol.343, p.129-218

2019

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A short sequence in the tail of SARS-CoV-2 envelope protein controls accessibility of its PDZ-binding motif to the cytoplasm

The Journal of biological chemistry, 2024-01, Vol.300 (1), p.105575, Article 105575

2024

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Structural Features of Tight-Junction Proteins

International journal of molecular sciences, 2019-11, Vol.20 (23), p.6020

2019

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Structural insights into the activation mechanisms of human HtrA serine proteases

Archives of biochemistry and biophysics, 2017-05, Vol.621, p.6-23

2017

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The spatial architecture of protein function and adaptation

Nature (London), 2012-11, Vol.491 (7422), p.138-142

2012

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Mutual information analysis of mutation, nonlinearity, and triple interactions in proteins

Proteins, structure, function, and bioinformatics, 2023-01, Vol.91 (1), p.121-133

Erman, Burak

2023

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High dose of baicalin or baicalein can reduce tight junction integrity by partly targeting the first PDZ domain of zonula occludens-1 (ZO-1)

European journal of pharmacology, 2020-11, Vol.887, p.173436-173436, Article 173436

2020

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High-Throughput Production of a New Library of Human Single and Tandem PDZ Domains Allows Quantitative PDZ-Peptide Interaction Screening Through High-Throughput Holdup Assay

Methods in molecular biology (Clifton, N.J.), 2019, Vol.2025, p.439

2019

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Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay

Journal of cell science, 2016-10, Vol.129 (20), p.3892-3902

2016

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Interactions with PDZ proteins diversify voltage‐gated calcium channel signaling

Journal of neuroscience research, 2021-01, Vol.99 (1), p.332-348

2021

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Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners

Journal of molecular biology, 2020-11, Vol.432 (22), p.5920-5937

2020

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Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes

Proceedings of the National Academy of Sciences - PNAS, 2014-02, Vol.111 (7), p.2542-2547

2014

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PTEN recruitment controls synaptic and cognitive function in Alzheimer's models

Nature neuroscience, 2016-03, Vol.19 (3), p.443-453

2016

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Inhibitors against Two PDZ Domains of MDA-9 Suppressed Migration of Breast Cancer Cells

International journal of molecular sciences, 2023-02, Vol.24 (4), p.3431

2023

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Proteome‐wide analysis of phospho‐regulated PDZ domain interactions

Molecular systems biology, 2018-08, Vol.14 (8), p.e8129-n/a

2018

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Structure-based optimization of a PDZ-binding motif within a viral peptide stimulates neurite outgrowth

The Journal of biological chemistry, 2019-09, Vol.294 (37), p.13755-13768

2019

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Ensemble-Based Analysis of the Dynamic Allostery in the PSD-95 PDZ3 Domain in Relation to the General Variability of PDZ Structures

International journal of molecular sciences, 2020-11, Vol.21 (21), p.8348

2020

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Selective function of the PDZ domain of Dishevelled in noncanonical Wnt signalling

Journal of cell science, 2022-06, Vol.135 (11)

2022

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Roles of the PDZ‐binding motif of HPV 16 E6 protein in oncogenic transformation of human cervical keratinocytes

Cancer science, 2017-07, Vol.108 (7), p.1303-1309

2017

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Whirlin and PDZ Domain-containing 7 (PDZD7) Proteins Are Both Required to Form the Quaternary Protein Complex Associated with Usher Syndrome Type 2

The Journal of biological chemistry, 2014-12, Vol.289 (52), p.36070-36088

2014

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Functional interplay between protein domains in a supramodular structure involving the postsynaptic density protein PSD-95

The Journal of biological chemistry, 2020-02, Vol.295 (7), p.1992-2000

2020

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Structures and target recognition modes of PDZ domains: recurring themes and emerging pictures

Tight junction formation by a claudin mutant lacking the COOH‐terminal PDZ domain‐binding motif

Lock and chop: A novel method for the generation of a PICK1 PDZ domain and piperidine‐based inhibitor co‐crystal structure

The PDZ protein SCRIB regulates sodium/iodide symporter (NIS) expression at the basolateral plasma membrane

Emerging Themes in PDZ Domain Signaling: Structure, Function, and Inhibition

A short sequence in the tail of SARS-CoV-2 envelope protein controls accessibility of its PDZ-binding motif to the cytoplasm

Structural Features of Tight-Junction Proteins

Structural insights into the activation mechanisms of human HtrA serine proteases

The spatial architecture of protein function and adaptation

Mutual information analysis of mutation, nonlinearity, and triple interactions in proteins

High dose of baicalin or baicalein can reduce tight junction integrity by partly targeting the first PDZ domain of zonula occludens-1 (ZO-1)

High-Throughput Production of a New Library of Human Single and Tandem PDZ Domains Allows Quantitative PDZ-Peptide Interaction Screening Through High-Throughput Holdup Assay

Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay

Interactions with PDZ proteins diversify voltage‐gated calcium channel signaling

Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners

Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes

PTEN recruitment controls synaptic and cognitive function in Alzheimer's models

Inhibitors against Two PDZ Domains of MDA-9 Suppressed Migration of Breast Cancer Cells

Proteome‐wide analysis of phospho‐regulated PDZ domain interactions

Structure-based optimization of a PDZ-binding motif within a viral peptide stimulates neurite outgrowth

Ensemble-Based Analysis of the Dynamic Allostery in the PSD-95 PDZ3 Domain in Relation to the General Variability of PDZ Structures

Selective function of the PDZ domain of Dishevelled in noncanonical Wnt signalling

Roles of the PDZ‐binding motif of HPV 16 E6 protein in oncogenic transformation of human cervical keratinocytes

Whirlin and PDZ Domain-containing 7 (PDZD7) Proteins Are Both Required to Form the Quaternary Protein Complex Associated with Usher Syndrome Type 2

Functional interplay between protein domains in a supramodular structure involving the postsynaptic density protein PSD-95

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