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Chemically induced mouse models of acute and chronic intestinal inflammation

Nature protocols, 2017-07, Vol.12 (7), p.1295-1309

2017

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Co-occurrence of enzyme domains guides the discovery of an oxazolone synthetase

Nature chemical biology, 2021-07, Vol.17 (7), p.794-799

2021

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Mapping a Systematic Ribozyme Fitness Landscape Reveals a Frustrated Evolutionary Network for Self-Aminoacylating RNA

Journal of the American Chemical Society, 2019-04, Vol.141 (15), p.6213-6223

2019

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The tyrosinase inhibitory effects of isoxazolone derivatives with a (Z)-β-phenyl-α, β-unsaturated carbonyl scaffold

Bioorganic & medicinal chemistry, 2018-08, Vol.26 (14), p.3882-3889

2018

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Design, Synthesis, and Biological Evaluation of a Series of Oxazolone Carboxamides as a Novel Class of Acid Ceramidase Inhibitors

Journal of medicinal chemistry, 2020-12, Vol.63 (24), p.15821-15851

2020

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Nickel/Bis(oxazoline)-Catalyzed Asymmetric Kumada Reactions of Alkyl Electrophiles: Cross-Couplings of Racemic α-Bromoketones

Journal of the American Chemical Society, 2010-02, Vol.132 (4), p.1264-1266

2010

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The discovery of oxazolones-grafted spirooxindoles via three-component diversity oriented synthesis and their preliminary biological evaluation

Bioorganic & medicinal chemistry letters, 2015-09, Vol.25 (17), p.3585-3591

2015

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Partially Hydrolyzed Poly(n‑propyl-2-oxazoline): Synthesis, Aqueous Solution Properties, and Preparation of Gene Delivery Systems

Biomacromolecules, 2016-11, Vol.17 (11), p.3580-3590

2016

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Synthesis of novel compounds containing morpholine and 5(4H)-oxazolone rings as potent tyrosinase inhibitors

Bioorganic & medicinal chemistry, 2015-11, Vol.23 (21), p.7089-7094

2015

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Oxazolone-1,2,3-Triazole Hybrids: Design, Synthesis and Antimicrobial Evaluation

Current topics in medicinal chemistry, 2018-01, Vol.18 (17), p.1506-1513

2018

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The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis

The Journal of immunology (1950), 2017-07, Vol.199 (2), p.718-733

2017

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Oxazolones: New tyrosinase inhibitors; synthesis and their structure–activity relationships

Bioorganic & medicinal chemistry, 2006-09, Vol.14 (17), p.6027-6033

2006

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Cis-trans isomerization is not rate determining for b2 ion structures: A guided ion beam and computational study of the decomposition of H+(GlyProAla)

International journal of mass spectrometry, 2020-12, Vol.458, p.116434, Article 116434

2020

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Characterization of a Hapten-Induced, Murine Model with Multiple Features of Atopic Dermatitis: Structural, Immunologic, and Biochemical Changes following Single Versus Multiple Oxazolone Challenges

Journal of investigative dermatology, 2008-01, Vol.128 (1), p.79-86

2008

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Synthesis, Antimicrobial, Anti-Virulence and Anticancer Evaluation of New 5(4 H )-Oxazolone-Based Sulfonamides

Molecules (Basel, Switzerland), 2022-01, Vol.27 (3), p.671

2022

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Sulfate-reducing bacteria stimulate gut immune responses and contribute to inflammation in experimental colitis

Life sciences (1973), 2017-11, Vol.189, p.29-38

2017

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STAT6 deficiency ameliorates severity of oxazolone colitis by decreasing expression of claudin-2 and Th2-inducing cytokines

The Journal of immunology (1950), 2013-02, Vol.190 (4), p.1849-1858

2013

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5-(4 H )-Oxazolones and Their Benzamides as Potential Bioactive Small Molecules

Molecules (Basel, Switzerland), 2020-07, Vol.25 (14), p.3173

2020

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Synthesis of novel azo compounds containing 5(4H)-oxazolone ring as potent tyrosinase inhibitors

Bioorganic & medicinal chemistry, 2013-04, Vol.21 (7), p.2088-2092

2013

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Exploring of novel oxazolones and imidazolones as anti-inflammatory and analgesic candidates with cyclooxygenase inhibitory action

Future medicinal chemistry, 2024, Vol.16 (10), p.963-981

2024

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Lead Optimization and Modulation of hERG Activity in a Series of Aminooxazoline Xanthene β‑Site Amyloid Precursor Protein Cleaving Enzyme (BACE1) Inhibitors

Journal of medicinal chemistry, 2014-12, Vol.57 (23), p.9796-9810

2014

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A Modified Oxazolone Dye Dedicated to Spectroscopy and Optoelectronics

Journal of organic chemistry, 2022-06, Vol.87 (11), p.7319-7332

2022

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Palladium-Catalyzed Intramolecular Cyclization of Ynamides: Synthesis of 4‑Halo-oxazolones

Journal of organic chemistry, 2015-04, Vol.80 (7), p.3480-3487

2015

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Synthesis of Nirmatrelvir: Development of an Efficient, Scalable Process to Generate the Western Fragment

Organic process research & development, 2023-12, Vol.27 (12), p.2240-2249

2023

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MbnC Is Not Required for the Formation of the N-Terminal Oxazolone in the Methanobactin from Methylosinus trichosporium OB3b

Applied and environmental microbiology, 2022-01, Vol.88 (2), p.e0184121

2022

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Chemically induced mouse models of acute and chronic intestinal inflammation

Co-occurrence of enzyme domains guides the discovery of an oxazolone synthetase

Mapping a Systematic Ribozyme Fitness Landscape Reveals a Frustrated Evolutionary Network for Self-Aminoacylating RNA

The tyrosinase inhibitory effects of isoxazolone derivatives with a (Z)-β-phenyl-α, β-unsaturated carbonyl scaffold

Design, Synthesis, and Biological Evaluation of a Series of Oxazolone Carboxamides as a Novel Class of Acid Ceramidase Inhibitors

Nickel/Bis(oxazoline)-Catalyzed Asymmetric Kumada Reactions of Alkyl Electrophiles: Cross-Couplings of Racemic α-Bromoketones

The discovery of oxazolones-grafted spirooxindoles via three-component diversity oriented synthesis and their preliminary biological evaluation

Partially Hydrolyzed Poly(n‑propyl-2-oxazoline): Synthesis, Aqueous Solution Properties, and Preparation of Gene Delivery Systems

Synthesis of novel compounds containing morpholine and 5(4H)-oxazolone rings as potent tyrosinase inhibitors

Oxazolone-1,2,3-Triazole Hybrids: Design, Synthesis and Antimicrobial Evaluation

The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis

Oxazolones: New tyrosinase inhibitors; synthesis and their structure–activity relationships

Cis-trans isomerization is not rate determining for b2 ion structures: A guided ion beam and computational study of the decomposition of H+(GlyProAla)

Characterization of a Hapten-Induced, Murine Model with Multiple Features of Atopic Dermatitis: Structural, Immunologic, and Biochemical Changes following Single Versus Multiple Oxazolone Challenges

Synthesis, Antimicrobial, Anti-Virulence and Anticancer Evaluation of New 5(4 H )-Oxazolone-Based Sulfonamides

Sulfate-reducing bacteria stimulate gut immune responses and contribute to inflammation in experimental colitis

STAT6 deficiency ameliorates severity of oxazolone colitis by decreasing expression of claudin-2 and Th2-inducing cytokines

5-(4 H )-Oxazolones and Their Benzamides as Potential Bioactive Small Molecules

Synthesis of novel azo compounds containing 5(4H)-oxazolone ring as potent tyrosinase inhibitors

Exploring of novel oxazolones and imidazolones as anti-inflammatory and analgesic candidates with cyclooxygenase inhibitory action

Lead Optimization and Modulation of hERG Activity in a Series of Aminooxazoline Xanthene β‑Site Amyloid Precursor Protein Cleaving Enzyme (BACE1) Inhibitors

A Modified Oxazolone Dye Dedicated to Spectroscopy and Optoelectronics

Palladium-Catalyzed Intramolecular Cyclization of Ynamides: Synthesis of 4‑Halo-oxazolones

Synthesis of Nirmatrelvir: Development of an Efficient, Scalable Process to Generate the Western Fragment

MbnC Is Not Required for the Formation of the N-Terminal Oxazolone in the Methanobactin from Methylosinus trichosporium OB3b

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