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Molecular mechanisms of inflammasome signaling

Journal of leukocyte biology, 2018-02, Vol.103 (2), p.233-257

2018

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Caspase-1 Engagement and TLR-Induced c-FLIP Expression Suppress ASC/Caspase-8-Dependent Apoptosis by Inflammasome Sensors NLRP1b and NLRC4

Cell reports (Cambridge), 2017-12, Vol.21 (12), p.3427-3444

2017

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Emerging Activators and Regulators of Inflammasomes and Pyroptosis

Trends in immunology, 2019-11, Vol.40 (11), p.1035-1052

2019

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Epigenetic hypomethylation and upregulation of NLRC4 and NLRP12 in Kawasaki disease

Oncotarget, 2018-04, Vol.9 (27), p.18939-18948

2018

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The NLRP3 inflammasome drives inflammation in ischemia/reperfusion injury after transient middle cerebral artery occlusion in mice

Brain, behavior, and immunity, 2021-02, Vol.92, p.223-233

2021

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The Inflammasomes and Autoinflammatory Syndromes

Annual review of pathology, 2015-01, Vol.10 (1), p.395-424

2015

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The Salmonella pathogenicity island‐2 subverts human NLRP3 and NLRC4 inflammasome responses

Journal of leukocyte biology, 2019-02, Vol.105 (2), p.401-410

2019

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A 360° view of the inflammasome: Mechanisms of activation, cell death, and diseases

Cell, 2023-05, Vol.186 (11), p.2288-2312

2023

Volltextzugriff (PDF)

The NAIP/NLRC4 inflammasome in infection and pathology

Molecular aspects of medicine, 2020-12, Vol.76, p.100863-100863, Article 100863

2020

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Broad detection of bacterial type III secretion system and flagellin proteins by the human NAIP/NLRC4 inflammasome

Proceedings of the National Academy of Sciences - PNAS, 2017-12, Vol.114 (50), p.13242-13247

2017

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Bacterial Outer Membrane Vesicle-Mediated Cytosolic Delivery of Flagellin Triggers Host NLRC4 Canonical Inflammasome Signaling

Frontiers in immunology, 2020-11, Vol.11, p.581165-581165

2020

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Autoinflammatory mutation in NLRC4 reveals a leucine-rich repeat (LRR)–LRR oligomerization interface

Journal of allergy and clinical immunology, 2018-12, Vol.142 (6), p.1956-1967.e6

2018

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NLRC4 gain-of-function variant is identified in a patient with systemic lupus erythematosus

Clinical immunology (Orlando, Fla.), 2023-10, Vol.255, p.109731-109731, Article 109731

2023

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Salmonella spvC Gene Inhibits Autophagy of Host Cells and Suppresses NLRP3 as Well as NLRC4

Frontiers in immunology, 2021-07, Vol.12, p.639019-639019

2021

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Cytosolic Recognition of Microbes and Pathogens: Inflammasomes in Action

Microbiology and molecular biology reviews, 2018-12, Vol.82 (4), p.1

2018

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Iraqi propolis increases degradation of IL-1β and NLRC4 by autophagy following Pseudomonas aeruginosa infection

Microbes and infection, 2018-02, Vol.20 (2), p.89-100

2018

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Inflammasome assembly in neurodegenerative diseases

Trends in neurosciences (Regular ed.), 2023-10, Vol.46 (10), p.814-831

2023

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Monitoring of Inflammasome Activation of Macrophages and Microglia In Vitro, Part 1: Cell Preparation and Inflammasome Stimulation

Methods in molecular biology (Clifton, N.J.), 2024, Vol.2713, p.407

2024

Volltextzugriff (PDF)

NAIP-NLRC4 Inflammasomes Coordinate Intestinal Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and -8

Immunity (Cambridge, Mass.), 2017-04, Vol.46 (4), p.649-659

2017

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Enhanced IL-1β Release Following NLRP3 and AIM2 Inflammasome Stimulation Is Linked to mtROS in Airway Macrophages in Pulmonary Fibrosis

Frontiers in immunology, 2021-06, Vol.12, p.661811-661811

2021

Volltextzugriff (PDF)

Evolutionary loss of inflammasomes in the Carnivora and implications for the carriage of zoonotic infections

Cell reports (Cambridge), 2021-08, Vol.36 (8), p.109614-109614, Article 109614

2021

Volltextzugriff (PDF)

Emerging Concepts about NAIP/NLRC4 Inflammasomes

Frontiers in immunology, 2014-07, Vol.5, p.309-309

2014

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Self-assembled flagella protein nanofibers induce enhanced mucosal immunity

Biomaterials, 2022-09, Vol.288, p.121733-121733, Article 121733

2022

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Flagellin/NLRC4 Pathway Rescues NLRP3-Inflammasome Defect in Dendritic Cells From HIV-Infected Patients: Perspective for New Adjuvant in Immunocompromised Individuals

Frontiers in immunology, 2019-06, Vol.10, p.1291-1291

2019

Volltextzugriff (PDF)

Evidence that NLRC4 inflammasome mediates apoptotic and pyroptotic microglial death following ischemic stroke

Brain, behavior, and immunity, 2019-01, Vol.75, p.34-47

2019

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Molecular mechanisms of inflammasome signaling

Caspase-1 Engagement and TLR-Induced c-FLIP Expression Suppress ASC/Caspase-8-Dependent Apoptosis by Inflammasome Sensors NLRP1b and NLRC4

Emerging Activators and Regulators of Inflammasomes and Pyroptosis

Epigenetic hypomethylation and upregulation of NLRC4 and NLRP12 in Kawasaki disease

The NLRP3 inflammasome drives inflammation in ischemia/reperfusion injury after transient middle cerebral artery occlusion in mice

The Inflammasomes and Autoinflammatory Syndromes

The Salmonella pathogenicity island‐2 subverts human NLRP3 and NLRC4 inflammasome responses

A 360° view of the inflammasome: Mechanisms of activation, cell death, and diseases

The NAIP/NLRC4 inflammasome in infection and pathology

Broad detection of bacterial type III secretion system and flagellin proteins by the human NAIP/NLRC4 inflammasome

Bacterial Outer Membrane Vesicle-Mediated Cytosolic Delivery of Flagellin Triggers Host NLRC4 Canonical Inflammasome Signaling

Autoinflammatory mutation in NLRC4 reveals a leucine-rich repeat (LRR)–LRR oligomerization interface

NLRC4 gain-of-function variant is identified in a patient with systemic lupus erythematosus

Salmonella spvC Gene Inhibits Autophagy of Host Cells and Suppresses NLRP3 as Well as NLRC4

Cytosolic Recognition of Microbes and Pathogens: Inflammasomes in Action

Iraqi propolis increases degradation of IL-1β and NLRC4 by autophagy following Pseudomonas aeruginosa infection

Inflammasome assembly in neurodegenerative diseases

Monitoring of Inflammasome Activation of Macrophages and Microglia In Vitro, Part 1: Cell Preparation and Inflammasome Stimulation

NAIP-NLRC4 Inflammasomes Coordinate Intestinal Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and -8

Enhanced IL-1β Release Following NLRP3 and AIM2 Inflammasome Stimulation Is Linked to mtROS in Airway Macrophages in Pulmonary Fibrosis

Evolutionary loss of inflammasomes in the Carnivora and implications for the carriage of zoonotic infections

Emerging Concepts about NAIP/NLRC4 Inflammasomes

Self-assembled flagella protein nanofibers induce enhanced mucosal immunity

Flagellin/NLRC4 Pathway Rescues NLRP3-Inflammasome Defect in Dendritic Cells From HIV-Infected Patients: Perspective for New Adjuvant in Immunocompromised Individuals

Evidence that NLRC4 inflammasome mediates apoptotic and pyroptotic microglial death following ischemic stroke

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