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Thrombo-inflammation in acute ischaemic stroke - implications for treatment

Nature reviews. Neurology, 2019-08, Vol.15 (8), p.473-481

2019

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NLPR3 inflammasome inhibition alleviates hypoxic endothelial cell death in vitro and protects blood-brain barrier integrity in murine stroke

Cell death & disease, 2021-12, Vol.13 (1), p.20-20, Article 20

2021

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Beyond recanalization - a call for action in acute stroke

Nature reviews. Neurology, 2020-11, Vol.16 (11), p.591-592

2020

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Structure and functional mapping of the KRAB‐KAP1 repressor complex

The EMBO journal, 2022-12, Vol.41 (24), p.e111179-n/a

2022

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Ischaemic stroke: a thrombo‐inflammatory disease?

The Journal of physiology, 2011-09, Vol.589 (17), p.4115-4123

2011

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Structure of KAP1 tripartite motif identifies molecular interfaces required for retroelement silencing

Proceedings of the National Academy of Sciences - PNAS, 2019-07, Vol.116 (30), p.15042-15051

2019

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Crystal structure and biochemical activity of the macrodomain from rubella virus p150

Journal of virology, 2024-01, Vol.98 (2), p.e0177723

2024

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Molecular mechanisms of thrombus formation in ischemic stroke: novel insights and targets for treatment

Blood, 2008-11, Vol.112 (9), p.3555-3562

2008

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Only severe thrombocytopenia results in bleeding and defective thrombus formation in mice

Blood, 2013-06, Vol.121 (24), p.4938-4947

2013

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Combating innate inflammation: a new paradigm for acute treatment of stroke?

Annals of the New York Academy of Sciences, 2010-10, Vol.1207 (1), p.149-154

2010

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Orai1 (CRACM1) is the platelet SOC channel and essential for pathological thrombus formation

Blood, 2009-02, Vol.113 (9), p.2056-2063

2009

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pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread

PLoS pathogens, 2021-08, Vol.17 (8), p.e1009824-e1009824

2021

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Immunohistological Analysis of Neutrophils and Neutrophil Extracellular Traps in Human Thrombemboli Causing Acute Ischemic Stroke

International journal of molecular sciences, 2020-10, Vol.21 (19), p.1

2020

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Factor XIIa Inhibitor Recombinant Human Albumin Infestin-4 Abolishes Occlusive Arterial Thrombus Formation Without Affecting Bleeding

Circulation (New York, N.Y.), 2010-04, Vol.121 (13), p.1510-1517

2010

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Local Cerebral Recombinant Tissue Plasminogen Activator Concentrations During Acute Stroke

JAMA neurology, 2021-05, Vol.78 (5), p.615

2021

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The Novel Oral Syk Inhibitor, Bl1002494, Protects Mice From Arterial Thrombosis and Thromboinflammatory Brain Infarction

Arteriosclerosis, thrombosis, and vascular biology, 2016-06, Vol.36 (6), p.1247

2016

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Gray platelet syndrome and defective thrombo-inflammation in Nbeal2-deficient mice

The Journal of clinical investigation, 2013-08, Vol.123 (8), p.3331-3342

2013

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Regulation and Release of Vasoactive Endoglin by Brain Endothelium in Response to Hypoxia/Reoxygenation in Stroke

International journal of molecular sciences, 2022-07, Vol.23 (13), p.7085

2022

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Description of a Novel Phosphodiesterase (PDE)-3 Inhibitor Protecting Mice From Ischemic Stroke Independent From Platelet Function

Stroke (1970), 2019-02, Vol.50 (2), p.478-486

2019

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The calcium sensor STIM1 is an essential mediator of arterial thrombosis and ischemic brain infarction

The Journal of experimental medicine, 2008-07, Vol.205 (7), p.1583-1591

2008

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Loss of Orai2-Mediated Capacitative Ca2+ Entry Is Neuroprotective in Acute Ischemic Stroke

Stroke (1970), 2019-11, Vol.50 (11), p.3238-3245

2019

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Human Brain Endothelial CXCR2 is Inflammation- Inducible and Mediates CXCL5- and CXCL8-Triggered Paraendothelial Barrier Breakdown

International journal of molecular sciences, 2019-01, Vol.20 (3), p.602

2019

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STIM2 regulates capacitive Ca2+ entry in neurons and plays a key role in hypoxic neuronal cell death

Science signaling, 2009-10, Vol.2 (93), p.ra67

2009

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Mesencephalic Electrical Stimulation Reduces Neuroinflammation after Photothrombotic Stroke in Rats by Targeting the Cholinergic Anti-Inflammatory Pathway

International journal of molecular sciences, 2021-01, Vol.22 (3), p.1254

2021

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Thrombo-inflammation in acute ischaemic stroke - implications for treatment

NLPR3 inflammasome inhibition alleviates hypoxic endothelial cell death in vitro and protects blood-brain barrier integrity in murine stroke

Beyond recanalization - a call for action in acute stroke

Structure and functional mapping of the KRAB‐KAP1 repressor complex

Ischaemic stroke: a thrombo‐inflammatory disease?

Structure of KAP1 tripartite motif identifies molecular interfaces required for retroelement silencing

Crystal structure and biochemical activity of the macrodomain from rubella virus p150

Molecular mechanisms of thrombus formation in ischemic stroke: novel insights and targets for treatment

Only severe thrombocytopenia results in bleeding and defective thrombus formation in mice

Combating innate inflammation: a new paradigm for acute treatment of stroke?

Orai1 (CRACM1) is the platelet SOC channel and essential for pathological thrombus formation

pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread

Immunohistological Analysis of Neutrophils and Neutrophil Extracellular Traps in Human Thrombemboli Causing Acute Ischemic Stroke

Factor XIIa Inhibitor Recombinant Human Albumin Infestin-4 Abolishes Occlusive Arterial Thrombus Formation Without Affecting Bleeding

Local Cerebral Recombinant Tissue Plasminogen Activator Concentrations During Acute Stroke

Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration

The Novel Oral Syk Inhibitor, Bl1002494, Protects Mice From Arterial Thrombosis and Thromboinflammatory Brain Infarction

Gray platelet syndrome and defective thrombo-inflammation in Nbeal2-deficient mice

Regulation and Release of Vasoactive Endoglin by Brain Endothelium in Response to Hypoxia/Reoxygenation in Stroke

Description of a Novel Phosphodiesterase (PDE)-3 Inhibitor Protecting Mice From Ischemic Stroke Independent From Platelet Function

The calcium sensor STIM1 is an essential mediator of arterial thrombosis and ischemic brain infarction

Loss of Orai2-Mediated Capacitative Ca2+ Entry Is Neuroprotective in Acute Ischemic Stroke

Human Brain Endothelial CXCR2 is Inflammation- Inducible and Mediates CXCL5- and CXCL8-Triggered Paraendothelial Barrier Breakdown

STIM2 regulates capacitive Ca2+ entry in neurons and plays a key role in hypoxic neuronal cell death

Mesencephalic Electrical Stimulation Reduces Neuroinflammation after Photothrombotic Stroke in Rats by Targeting the Cholinergic Anti-Inflammatory Pathway

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