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Privileged Scaffolds in Drug Discovery

1, 2023

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Recent advance in oxazole-based medicinal chemistry

European journal of medicinal chemistry, 2018-01, Vol.144, p.444-492

2018

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N‑Terminal Liver-Expressed Antimicrobial Peptide 2 (LEAP2) Region Exhibits Inverse Agonist Activity toward the Ghrelin Receptor

Journal of medicinal chemistry, 2019-01, Vol.62 (2), p.965-973

2019

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Synergy and antagonism in natural product extracts: when 1 + 1 does not equal 2

Natural product reports, 2019-06, Vol.36 (6), p.869-888

2019

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Hot-Spots of Mcl-1 Protein

Journal of medicinal chemistry, 2020-02, Vol.63 (3), p.928-943

2020

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A Comparative Assessment Study of Known Small-Molecule Keap1−Nrf2 Protein–Protein Interaction Inhibitors: Chemical Synthesis, Binding Properties, and Cellular Activity

Journal of medicinal chemistry, 2019-09, Vol.62 (17), p.8028-8052

2019

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Anti-biofilm Agents against Pseudomonas aeruginosa: A Structure–Activity Relationship Study of C‑Glycosidic LecB Inhibitors

Journal of medicinal chemistry, 2019-10, Vol.62 (20), p.9201-9216

2019

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Carotenoids as natural functional pigments

Journal of natural medicines, 2020-01, Vol.74 (1), p.1-16

Maoka, Takashi

2020

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Atypical Elements in Drug Design

Schwarz, Jacob

1st ed. 2016, 2016

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Traditional Chinese herbal medicine at the forefront battle against COVID-19: Clinical experience and scientific basis

Phytomedicine (Stuttgart), 2021-01, Vol.80, p.153337-153337, Article 153337

2021

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Triptolide: Medicinal chemistry, chemical biology and clinical progress

European journal of medicinal chemistry, 2019-08, Vol.176, p.378-392

2019

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Understanding the Molecular Mechanisms of the Interplay Between Herbal Medicines and Gut Microbiota

Medicinal research reviews, 2017-09, Vol.37 (5), p.1140-1185

2017

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Marine Natural Products in Medicinal Chemistry

ACS medicinal chemistry letters, 2018-10, Vol.9 (10), p.959-961

Jiménez, Carlos

2018

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A BOILED-Egg To Predict Gastrointestinal Absorption and Brain Penetration of Small Molecules

ChemMedChem, 2016-06, Vol.11 (11), p.1117-1121

2016

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Ruthenium(II) Complex Containing a Redox-Active Semiquinonate Ligand as a Potential Chemotherapeutic Agent: From Synthesis to In Vivo Studies

Journal of medicinal chemistry, 2020-05, Vol.63 (10), p.5568-5584

2020

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A review: FDA-approved fluorine-containing small molecules from 2015 to 2022

European journal of medicinal chemistry, 2023-11, Vol.260, p.115758, Article 115758

2023

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Thiazole: A Review on Chemistry, Synthesis and Therapeutic Importance of its Derivatives

Current topics in medicinal chemistry, 2016-10, Vol.16 (26), p.2841-2862

2016

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Phytochemical and pharmacological attributes of piperine: A bioactive ingredient of black pepper

European journal of medicinal chemistry, 2019-08, Vol.176, p.149-161

2019

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Synthesis of Bleomycin-Inspired RNA Ligands Targeting the Biogenesis of Oncogenic miRNAs

Journal of medicinal chemistry, 2023-08, Vol.66 (15), p.10639-10657

2023

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Traditional herbal medicine: Therapeutic potential in rheumatoid arthritis

Journal of ethnopharmacology, 2021-10, Vol.279, p.114368-114368, Article 114368

2021

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Motivational Interviewing as an Intervention to Improve Antiretroviral Treatment Initiation Among People who Inject Drugs (PWID): A Pilot Study in Jakarta and Bandung, Indonesia

Current Drug Research Reviews, 2024-01, Vol.16 (2), p.228-236

2024

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Ligand- and Structure-based Approaches for Transmembrane Transporter Modeling

Current Drug Research Reviews, 2024-01, Vol.16 (2), p.81-93

2024

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Polymeric Encapsulation of a Ru(II)-Based Photosensitizer for Folate-Targeted Photodynamic Therapy of Drug Resistant Cancers

Journal of medicinal chemistry, 2021-04, Vol.64 (8), p.4612-4622

2021

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A Ru(II) polypyridyl complex bearing aldehyde functions as a versatile synthetic precursor for long-wavelength absorbing photodynamic therapy photosensitizers

Bioorganic & medicinal chemistry, 2019-06, Vol.27 (12), p.2666-2675

2019

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Discovery, Structure–Activity Relationships, and In Vivo Activity of Dihydropyridone Agonists of the Bile Acid Receptor TGR5

Journal of medicinal chemistry, 2023-09, Vol.66 (17), p.11732-11760

2023

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Privileged Scaffolds in Drug Discovery

Recent advance in oxazole-based medicinal chemistry

N‑Terminal Liver-Expressed Antimicrobial Peptide 2 (LEAP2) Region Exhibits Inverse Agonist Activity toward the Ghrelin Receptor

Synergy and antagonism in natural product extracts: when 1 + 1 does not equal 2

Hot-Spots of Mcl-1 Protein

A Comparative Assessment Study of Known Small-Molecule Keap1−Nrf2 Protein–Protein Interaction Inhibitors: Chemical Synthesis, Binding Properties, and Cellular Activity

Anti-biofilm Agents against Pseudomonas aeruginosa: A Structure–Activity Relationship Study of C‑Glycosidic LecB Inhibitors

Carotenoids as natural functional pigments

Atypical Elements in Drug Design

Traditional Chinese herbal medicine at the forefront battle against COVID-19: Clinical experience and scientific basis

Triptolide: Medicinal chemistry, chemical biology and clinical progress

Understanding the Molecular Mechanisms of the Interplay Between Herbal Medicines and Gut Microbiota

Marine Natural Products in Medicinal Chemistry

A BOILED-Egg To Predict Gastrointestinal Absorption and Brain Penetration of Small Molecules

Ruthenium(II) Complex Containing a Redox-Active Semiquinonate Ligand as a Potential Chemotherapeutic Agent: From Synthesis to In Vivo Studies

A review: FDA-approved fluorine-containing small molecules from 2015 to 2022

Thiazole: A Review on Chemistry, Synthesis and Therapeutic Importance of its Derivatives

Phytochemical and pharmacological attributes of piperine: A bioactive ingredient of black pepper

Synthesis of Bleomycin-Inspired RNA Ligands Targeting the Biogenesis of Oncogenic miRNAs

Traditional herbal medicine: Therapeutic potential in rheumatoid arthritis

Motivational Interviewing as an Intervention to Improve Antiretroviral Treatment Initiation Among People who Inject Drugs (PWID): A Pilot Study in Jakarta and Bandung, Indonesia

Ligand- and Structure-based Approaches for Transmembrane Transporter Modeling

Polymeric Encapsulation of a Ru(II)-Based Photosensitizer for Folate-Targeted Photodynamic Therapy of Drug Resistant Cancers

A Ru(II) polypyridyl complex bearing aldehyde functions as a versatile synthetic precursor for long-wavelength absorbing photodynamic therapy photosensitizers

Discovery, Structure–Activity Relationships, and In Vivo Activity of Dihydropyridone Agonists of the Bile Acid Receptor TGR5

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