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Altered Basal Lipid Metabolism Underlies the Functional Impairment of Naive CD8 + T Cells in Elderly Humans

The Journal of immunology (1950), 2022-02, Vol.208 (3), p.562-570

2022

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Comparison of T Cell Activities Mediated by Human TCRs and CARs That Use the Same Recognition Domains

The Journal of immunology (1950), 2018-02, Vol.200 (3), p.1088-1100

2018

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In vivo delivery of peptides and Toll-like receptor ligands by mannose-functionalized polymeric nanoparticles induces prophylactic and therapeutic anti-tumor immune responses in a melanoma model

Journal of controlled release, 2015-01, Vol.198, p.91-103

2015

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Similar antigen cross-presentation capacity and phagocytic functions in all freshly isolated human lymphoid organ-resident dendritic cells

The Journal of experimental medicine, 2013-05, Vol.210 (5), p.1035-1047

2013

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Exhaustion of tumor-specific CD8⁺ T cells in metastases from melanoma patients

The Journal of clinical investigation, 2011-06, Vol.121 (6), p.2350-2360

2011

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Immunotherapy Resistance by Inflammation-Induced Dedifferentiation

Cancer discovery, 2018-08, Vol.8 (8), p.935-943

2018

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Structural basis for ineffective T‐cell responses to MHC anchor residue‐improved “heteroclitic” peptides

European journal of immunology, 2015-02, Vol.45 (2), p.584-591

2015

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Myeloid-Derived Suppressor Cells Predict Survival of Patients with Advanced Melanoma: Comparison with Regulatory T Cells and NY-ESO-1- or Melan-A-Specific T Cells

Clinical cancer research, 2014-03, Vol.20 (6), p.1601-1609

2014

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Nano‐particle vaccination combined with TLR‐7 and ‐9 ligands triggers memory and effector CD8+ T‐cell responses in melanoma patients

European journal of immunology, 2012-11, Vol.42 (11), p.3049-3061

2012

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TCRs used in cancer gene therapy cross-react with MART-1/Melan-A tumor antigens via distinct mechanisms

The Journal of immunology (1950), 2011-09, Vol.187 (5), p.2453-2463

2011

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Case Report of a Fatal Serious Adverse Event Upon Administration of T Cells Transduced With a MART-1-specific T-cell Receptor

Molecular therapy, 2015-09, Vol.23 (9), p.1541-1550

2015

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Improving T Cell Receptor On-Target Specificity via Structure-Guided Design

Molecular therapy, 2019-02, Vol.27 (2), p.300-313

2019

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Subtle changes at the variable domain interface of the T-cell receptor can strongly increase affinity

The Journal of biological chemistry, 2018-02, Vol.293 (5), p.1820-1834

2018

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Specific increase in potency via structure-based design of a TCR

The Journal of immunology (1950), 2014-09, Vol.193 (5), p.2587-2599

2014

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Human T cells employ conserved AU‐rich elements to fine‐tune IFN‐γ production

European journal of immunology, 2020-07, Vol.50 (7), p.949-958

2020

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Low recurrence rates for in situ and invasive melanomas using Mohs micrographic surgery with melanoma antigen recognized by T cells 1 (MART-1) immunostaining: Tissue processing methodology to optimize pathologic staging and margin assessment

Journal of the American Academy of Dermatology, 2015-05, Vol.72 (5), p.840-850

2015

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Vaccination with LAG-3Ig (IMP321) and Peptides Induces Specific CD4 and CD8 T-Cell Responses in Metastatic Melanoma Patients--Report of a Phase I/IIa Clinical Trial

Clinical cancer research, 2016-03, Vol.22 (6), p.1330-1340

2016

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Mohs Micrographic Surgery Using MART-1 Immunostain in the Treatment of Invasive Melanoma and Melanoma In Situ

Dermatologic surgery, 2016-06, Vol.42 (6), p.733-744

2016

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Computational design of the affinity and specificity of a therapeutic T cell receptor

PLoS computational biology, 2014-02, Vol.10 (2), p.e1003478-e1003478

2014

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Multifunctional T-cell analyses to study response and progression in adoptive cell transfer immunotherapy

Cancer discovery, 2013-04, Vol.3 (4), p.418-429

2013

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Value of melanocytic-associated immunohistochemical markers in the diagnosis of malignant melanoma: a review and update

Human pathology, 2014-02, Vol.45 (2), p.191-205

Ordóñez, Nelson G., MD

2014

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Natural T cell autoreactivity to melanoma antigens: clonally expanded melanoma-antigen specific CD8 + memory T cells can be detected in healthy humans

Cancer Immunology, Immunotherapy, 2019-05, Vol.68 (5), p.709-720

2019

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Targeting human dendritic cells via DEC-205 using PLGA nanoparticles leads to enhanced cross-presentation of a melanoma-associated antigen

International journal of nanomedicine, 2014-01, Vol.9 (Issue 1), p.5231-5246

2014

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T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting

The Journal of biological chemistry, 2012-10, Vol.287 (44), p.37269-37281

2012

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Altered Basal Lipid Metabolism Underlies the Functional Impairment of Naive CD8 + T Cells in Elderly Humans

Comparison of T Cell Activities Mediated by Human TCRs and CARs That Use the Same Recognition Domains

Adoptive Transfer of MART-1 T-Cell Receptor Transgenic Lymphocytes and Dendritic Cell Vaccination in Patients with Metastatic Melanoma

In vivo delivery of peptides and Toll-like receptor ligands by mannose-functionalized polymeric nanoparticles induces prophylactic and therapeutic anti-tumor immune responses in a melanoma model

Similar antigen cross-presentation capacity and phagocytic functions in all freshly isolated human lymphoid organ-resident dendritic cells

Exhaustion of tumor-specific CD8⁺ T cells in metastases from melanoma patients

Immunotherapy Resistance by Inflammation-Induced Dedifferentiation

Structural basis for ineffective T‐cell responses to MHC anchor residue‐improved “heteroclitic” peptides

Myeloid-Derived Suppressor Cells Predict Survival of Patients with Advanced Melanoma: Comparison with Regulatory T Cells and NY-ESO-1- or Melan-A-Specific T Cells

Nano‐particle vaccination combined with TLR‐7 and ‐9 ligands triggers memory and effector CD8+ T‐cell responses in melanoma patients

TCRs used in cancer gene therapy cross-react with MART-1/Melan-A tumor antigens via distinct mechanisms

Case Report of a Fatal Serious Adverse Event Upon Administration of T Cells Transduced With a MART-1-specific T-cell Receptor

Improving T Cell Receptor On-Target Specificity via Structure-Guided Design

Subtle changes at the variable domain interface of the T-cell receptor can strongly increase affinity

Specific increase in potency via structure-based design of a TCR

Human T cells employ conserved AU‐rich elements to fine‐tune IFN‐γ production

Low recurrence rates for in situ and invasive melanomas using Mohs micrographic surgery with melanoma antigen recognized by T cells 1 (MART-1) immunostaining: Tissue processing methodology to optimize pathologic staging and margin assessment

Vaccination with LAG-3Ig (IMP321) and Peptides Induces Specific CD4 and CD8 T-Cell Responses in Metastatic Melanoma Patients--Report of a Phase I/IIa Clinical Trial

Mohs Micrographic Surgery Using MART-1 Immunostain in the Treatment of Invasive Melanoma and Melanoma In Situ

Computational design of the affinity and specificity of a therapeutic T cell receptor

Multifunctional T-cell analyses to study response and progression in adoptive cell transfer immunotherapy

Value of melanocytic-associated immunohistochemical markers in the diagnosis of malignant melanoma: a review and update

Natural T cell autoreactivity to melanoma antigens: clonally expanded melanoma-antigen specific CD8 + memory T cells can be detected in healthy humans

Targeting human dendritic cells via DEC-205 using PLGA nanoparticles leads to enhanced cross-presentation of a melanoma-associated antigen

T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting

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