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Aging of the immune system: Focus on inflammation and vaccination

European journal of immunology, 2016-10, Vol.46 (10), p.2286-2301

2016

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Cutting Edge: A Dual TLR2 and TLR7 Ligand Induces Highly Potent Humoral and Cell-Mediated Immune Responses

The Journal of immunology (1950), 2017-06, Vol.198 (11), p.4205-4209

2017

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Harnessing the Induction of CD8 + T-Cell Responses Through Metabolic Regulation by Pathogen-Recognition-Receptor Triggering in Antigen Presenting Cells

Frontiers in immunology, 2018-10, Vol.9, p.2372-2372

2018

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The TLR9 ligand CpG ODN 2006 is a poor adjuvant for the induction of de novo CD8 + T-cell responses in vitro

Scientific reports, 2020-07, Vol.10 (1), p.11620-11620, Article 11620

2020

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Pathogen-Specific T Cell Polyfunctionality Is a Correlate of T Cell Efficacy and Immune Protection

PloS one, 2015-06, Vol.10 (6), p.e0128714-e0128714

2015

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Evaluating cellular polyfunctionality with a novel polyfunctionality index

PloS one, 2012-07, Vol.7 (7), p.e42403-e42403

2012

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Naïve CD8 + T-Cells Engage a Versatile Metabolic Program Upon Activation in Humans and Differ Energetically From Memory CD8 + T-Cells

Frontiers in immunology, 2018-12, Vol.9, p.2736-2736

2018

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Exhausted cytotoxic control of Epstein-Barr virus in human lupus

PLoS pathogens, 2011-10, Vol.7 (10), p.e1002328-e1002328

2011

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Hepatitis B surface antigen reduction is associated with hepatitis B core-specific CD8+ T cell quality

Frontiers in immunology, 2023-10, Vol.14, p.1257113-1257113

2023

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Impaired Priming of SARS-CoV-2-Specific Naive CD8+ T Cells in Older Subjects

Frontiers in immunology, 2021-07, Vol.12, p.693054-693054

2021

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Model for predicting age-dependent safety and immunomodulatory effects of STING ligands in non-human primates

Molecular therapy. Methods & clinical development, 2023-03, Vol.28, p.99-115

2023

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Age-related decline of de novo T cell responsiveness as a cause of COVID-19 severity

GeroScience, 2020-08, Vol.42 (4), p.1015-1019

2020

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Does Inflammation Contribute to Cancer Incidence and Mortality during Aging? A Conceptual Review

Cancers, 2022-03, Vol.14 (7), p.1622

2022

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Accelerated immune senescence in HIV infection

Retrovirology, 2010-05, Vol.7 (S1), p.I30-I30, Article I30

Appay, Victor

2010

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Escape from highly effective public CD8+ T-cell clonotypes by HIV

Blood, 2011-08, Vol.118 (8), p.2138-2149

2011

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Naive T cells: The crux of cellular immune aging?

Experimental gerontology, 2014-06, Vol.54, p.90-93

2014

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Neutrophils in antiretroviral therapy–controlled HIV demonstrate hyperactivation associated with a specific IL-17/IL-22 environment

Journal of allergy and clinical immunology, 2014-11, Vol.134 (5), p.1142-1152.e5

2014

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Immune activation and CD8+ T-cell differentiation towards senescence in HIV-1 infection

PLoS biology, 2004-02, Vol.2 (2), p.E20-E20

2004

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Characterization of CD4+ CTLs Ex Vivo

The Journal of immunology (1950), 2002-06, Vol.168 (11), p.5954-5958

2002

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New chimeric TLR7/NOD2 agonist is a potent adjuvant to induce mucosal immune responses

EBioMedicine, 2020-08, Vol.58, p.102922-102922, Article 102922

2020

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Primary immune responses are negatively impacted by persistent herpesvirus infections in older people: results from an observational study on healthy subjects and a vaccination trial on subjects aged more than 70 years old

EBioMedicine, 2022-02, Vol.76, p.103852-103852, Article 103852

2022

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Functional Heterogeneity and High Frequencies of Cytomegalovirus-Specific CD8+ T Lymphocytes in Healthy Seropositive Donors

Journal of Virology, 2000-09, Vol.74 (17), p.8140-8150

2000

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Elderly human hematopoietic progenitor cells express cellular senescence markers and are more susceptible to pyroptosis

JCI insight, 2018-07, Vol.3 (13)

2018

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Aging of the immune system: Focus on inflammation and vaccination

Cutting Edge: A Dual TLR2 and TLR7 Ligand Induces Highly Potent Humoral and Cell-Mediated Immune Responses

Harnessing the Induction of CD8 + T-Cell Responses Through Metabolic Regulation by Pathogen-Recognition-Receptor Triggering in Antigen Presenting Cells

The TLR9 ligand CpG ODN 2006 is a poor adjuvant for the induction of de novo CD8 + T-cell responses in vitro

Pathogen-Specific T Cell Polyfunctionality Is a Correlate of T Cell Efficacy and Immune Protection

Evaluating cellular polyfunctionality with a novel polyfunctionality index

Naïve CD8 + T-Cells Engage a Versatile Metabolic Program Upon Activation in Humans and Differ Energetically From Memory CD8 + T-Cells

Exhausted cytotoxic control of Epstein-Barr virus in human lupus

Hepatitis B surface antigen reduction is associated with hepatitis B core-specific CD8+ T cell quality

A comparison of Sars-Cov-2 vaccine platforms: the CoviCompare project

Impaired Priming of SARS-CoV-2-Specific Naive CD8+ T Cells in Older Subjects

Model for predicting age-dependent safety and immunomodulatory effects of STING ligands in non-human primates

Immune response to the recombinant herpes zoster vaccine in people living with HIV over 50 years of age compared to non-HIV age-/gender-matched controls (SHINGR'HIV): a multicenter, international, non-randomized clinical trial study protocol

Age-related decline of de novo T cell responsiveness as a cause of COVID-19 severity

Does Inflammation Contribute to Cancer Incidence and Mortality during Aging? A Conceptual Review

Accelerated immune senescence in HIV infection

Escape from highly effective public CD8+ T-cell clonotypes by HIV

Naive T cells: The crux of cellular immune aging?

Neutrophils in antiretroviral therapy–controlled HIV demonstrate hyperactivation associated with a specific IL-17/IL-22 environment

Immune activation and CD8+ T-cell differentiation towards senescence in HIV-1 infection

Characterization of CD4+ CTLs Ex Vivo

New chimeric TLR7/NOD2 agonist is a potent adjuvant to induce mucosal immune responses

Primary immune responses are negatively impacted by persistent herpesvirus infections in older people: results from an observational study on healthy subjects and a vaccination trial on subjects aged more than 70 years old

Functional Heterogeneity and High Frequencies of Cytomegalovirus-Specific CD8+ T Lymphocytes in Healthy Seropositive Donors

Elderly human hematopoietic progenitor cells express cellular senescence markers and are more susceptible to pyroptosis

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