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Nuclear Localization of Mitochondrial TCA Cycle Enzymes as a Critical Step in Mammalian Zygotic Genome Activation

Cell, 2017-01, Vol.168 (1-2), p.210-223.e11

2017

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Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic intervention

PloS one, 2013-11, Vol.8 (11), p.e79977-e79977

2013

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NAD + Repletion Reverses Heart Failure With Preserved Ejection Fraction

Circulation research, 2021-05, Vol.128 (11), p.1629-1641

2021

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Very long chain fatty acid metabolism is required in acute myeloid leukemia

Blood, 2021-06, Vol.137 (25), p.3518-3532

2021

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Multilayered genetic and omics dissection of mitochondrial activity in a mouse reference population

Cell, 2014-09, Vol.158 (6), p.1415-1430

2014

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The mitochondrial 2-oxoadipate and 2-oxoglutarate dehydrogenase complexes share their E2 and E3 components for their function and both generate reactive oxygen species

Free radical biology & medicine, 2018-02, Vol.115, p.136-145

2018

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Calcium-sensitive pyruvate dehydrogenase phosphatase is required for energy metabolism, growth, differentiation, and infectivity of Trypanosoma cruzi

The Journal of biological chemistry, 2018-11, Vol.293 (45), p.17402-17417

2018

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c-Myc Programs Fatty Acid Metabolism and Dictates Acetyl-CoA Abundance and Fate

The Journal of biological chemistry, 2014-09, Vol.289 (36), p.25382-25392

2014

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Estimation of the hydrogen peroxide producing capacities of liver and cardiac mitochondria isolated from C57BL/6N and C57BL/6J mice

Free radical biology & medicine, 2019-05, Vol.135, p.15-27

2019

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2-Aminoadipic acid protects against obesity and diabetes

Journal of endocrinology, 2019-11, Vol.243 (2), p.111-123

2019

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An Alkynyl-Fucose Halts Hepatoma Cell Migration and Invasion by Inhibiting GDP-Fucose-Synthesizing Enzyme FX, TSTA3

Cell chemical biology, 2017-12, Vol.24 (12), p.1467-1478.e5

2017

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Citrate synthase variants improve yield of acetyl-CoA derived 3-hydroxybutyrate in Escherichia coli

Microbial cell factories, 2024-06, Vol.23 (1), p.173-14

2024

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Substrate Positioning Controls the Partition between Halogenation and Hydroxylation in the Aliphatic Halogenase, SyrB2

Proceedings of the National Academy of Sciences - PNAS, 2009-10, Vol.106 (42), p.17723-17728

2009

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Organic cation transporter 1 (OCT1) modulates multiple cardiometabolic traits through effects on hepatic thiamine content

PLoS biology, 2018-04, Vol.16 (4), p.e2002907-e2002907

2018

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Structure–function analyses of the G729R 2-oxoadipate dehydrogenase genetic variant associated with a disorder of l-lysine metabolism

The Journal of biological chemistry, 2020-06, Vol.295 (23), p.8078-8095

2020

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Molecular Mechanisms in Skeletal Muscle Underlying Insulin Resistance in Women Who Are Lean With Polycystic Ovary Syndrome

The journal of clinical endocrinology and metabolism, 2019-05, Vol.104 (5), p.1841-1854

2019

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Protein moonlighting elucidates the essential human pathway catalyzing lipoic acid assembly on its cognate enzymes

Proceedings of the National Academy of Sciences - PNAS, 2018-07, Vol.115 (30), p.E7063-E7072

2018

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Combining Protein and Metabolic Engineering Strategies for High-Level Production of O‑Acetylhomoserine in Escherichia coli

ACS synthetic biology, 2019-05, Vol.8 (5), p.1153-1167

2019

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A novel PDK1 inhibitor, JX06, inhibits glycolysis and induces apoptosis in multiple myeloma cells

Biochemical and biophysical research communications, 2022-01, Vol.587, p.153-159

2022

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Obesity-associated, but not obesity-independent, tumors respond to insulin by increasing mitochondrial glucose oxidation

PloS one, 2019-06, Vol.14 (6), p.e0218126-e0218126

2019

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PDH‐mediated metabolic flow is critical for skeletal muscle stem cell differentiation and myotube formation during regeneration in mice

The FASEB journal, 2019-07, Vol.33 (7), p.8094-8109

2019

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Generation of FX−/− and Gmds−/− CHOZN host cell lines for the production of afucosylated therapeutic antibodies

Biotechnology progress, 2021-01, Vol.37 (1), p.e3061-n/a

2021

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Mangiferin stimulates carbohydrate oxidation and protects against metabolic disorders induced by high-fat diets

Diabetes (New York, N.Y.), 2014-11, Vol.63 (11), p.3626-3636

2014

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Genetic basis of alpha-aminoadipic and alpha-ketoadipic aciduria

Journal of inherited metabolic disease, 2015-09, Vol.38 (5), p.873-879

2015

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The emerging importance of the α-keto acid dehydrogenase complexes in serving as intracellular and intercellular signaling platforms for the regulation of metabolism

Redox biology, 2024-06, Vol.72, p.103155, Article 103155

Mailloux, Ryan J.

2024

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Nuclear Localization of Mitochondrial TCA Cycle Enzymes as a Critical Step in Mammalian Zygotic Genome Activation

Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic intervention

NAD + Repletion Reverses Heart Failure With Preserved Ejection Fraction

Very long chain fatty acid metabolism is required in acute myeloid leukemia

Multilayered genetic and omics dissection of mitochondrial activity in a mouse reference population

The mitochondrial 2-oxoadipate and 2-oxoglutarate dehydrogenase complexes share their E2 and E3 components for their function and both generate reactive oxygen species

Calcium-sensitive pyruvate dehydrogenase phosphatase is required for energy metabolism, growth, differentiation, and infectivity of Trypanosoma cruzi

c-Myc Programs Fatty Acid Metabolism and Dictates Acetyl-CoA Abundance and Fate

Estimation of the hydrogen peroxide producing capacities of liver and cardiac mitochondria isolated from C57BL/6N and C57BL/6J mice

2-Aminoadipic acid protects against obesity and diabetes

An Alkynyl-Fucose Halts Hepatoma Cell Migration and Invasion by Inhibiting GDP-Fucose-Synthesizing Enzyme FX, TSTA3

Citrate synthase variants improve yield of acetyl-CoA derived 3-hydroxybutyrate in Escherichia coli

Substrate Positioning Controls the Partition between Halogenation and Hydroxylation in the Aliphatic Halogenase, SyrB2

Organic cation transporter 1 (OCT1) modulates multiple cardiometabolic traits through effects on hepatic thiamine content

Structure–function analyses of the G729R 2-oxoadipate dehydrogenase genetic variant associated with a disorder of l-lysine metabolism

Molecular Mechanisms in Skeletal Muscle Underlying Insulin Resistance in Women Who Are Lean With Polycystic Ovary Syndrome

Protein moonlighting elucidates the essential human pathway catalyzing lipoic acid assembly on its cognate enzymes

Combining Protein and Metabolic Engineering Strategies for High-Level Production of O‑Acetylhomoserine in Escherichia coli

A novel PDK1 inhibitor, JX06, inhibits glycolysis and induces apoptosis in multiple myeloma cells

Obesity-associated, but not obesity-independent, tumors respond to insulin by increasing mitochondrial glucose oxidation

PDH‐mediated metabolic flow is critical for skeletal muscle stem cell differentiation and myotube formation during regeneration in mice

Generation of FX−/− and Gmds−/− CHOZN host cell lines for the production of afucosylated therapeutic antibodies

Mangiferin stimulates carbohydrate oxidation and protects against metabolic disorders induced by high-fat diets

Genetic basis of alpha-aminoadipic and alpha-ketoadipic aciduria

The emerging importance of the α-keto acid dehydrogenase complexes in serving as intracellular and intercellular signaling platforms for the regulation of metabolism

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