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IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation

Cell host & microbe, 2019-06, Vol.25 (6), p.858-872.e13

2019

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Persistent HIV-1 replication maintains the tissue reservoir during therapy

Nature (London), 2016-02, Vol.530 (7588), p.51-56

2016

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Reactivation capacity by latency-reversing agents ex vivo correlates with the size of the HIV-1 reservoir

AIDS (London), 2017-01, Vol.31 (2), p.181-189

2017

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The Biology of the HIV-1 Latent Reservoir and Implications for Cure Strategies

Cell host & microbe, 2020-04, Vol.27 (4), p.519-530

2020

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SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef

Nature (London), 2015-10, Vol.526 (7572), p.218-223

2015

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HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis

Nature (London), 2016-08, Vol.536 (7616), p.349-353

2016

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CG dinucleotide suppression enables antiviral defence targeting non-self RNA

Nature (London), 2017-10, Vol.550 (7674), p.124-127

2017

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HIV: Shock and kill

Nature (London), 2012-07, Vol.487 (7408), p.439

Deeks, Steven G

2012

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Acetylation of Cytidine Residues Boosts HIV-1 Gene Expression by Increasing Viral RNA Stability

Cell host & microbe, 2020-08, Vol.28 (2), p.306-312.e6

2020

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Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations

Nature (London), 2015-01, Vol.517 (7534), p.381-385

2015

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Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

Nature (London), 2014-01, Vol.505 (7484), p.509-514

2014

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HIV therapy by a combination of broadly neutralizing antibodies in humanized mice

Nature (London), 2012-12, Vol.492 (7427), p.118-122

2012

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A humanized mouse-based HIV-1 viral outgrowth assay with higher sensitivity than in vitro qVOA in detecting latently infected cells from individuals on ART with undetectable viral loads

Virology (New York, N.Y.), 2017-07, Vol.507, p.135-139

2017

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CRISPR/Cas9-Derived Mutations Both Inhibit HIV-1 Replication and Accelerate Viral Escape

Cell reports (Cambridge), 2016-04, Vol.15 (3), p.481-489

2016

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HIV-1 Pol Gene Polymorphism and Antiretroviral Resistance Mutations in Treatment-Naive Adult Patients in French Guiana Between 2006 and 2012

AIDS research and human retroviruses, 2016-08, Vol.32 (8), p.801

2016

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Clinical targeting of HIV capsid protein with a long-acting small molecule

Nature (London), 2020-08, Vol.584 (7822), p.614-618

2020

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N(6)-methyladenosine of HIV-1 RNA regulates viral infection and HIV-1 Gag protein expression

eLife, 2016-07, Vol.5

2016

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HIV-1 Integrase Binds the Viral RNA Genome and Is Essential during Virion Morphogenesis

Cell, 2016-08, Vol.166 (5), p.1257-1268.e12

2016

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Relationship between intact HIV-1 proviruses in circulating CD4⁺ T cells and rebound viruses emerging during treatment interruption

Proceedings of the National Academy of Sciences - PNAS, 2018-11, Vol.115 (48), p.E11341-E11348

2018

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Envelope glycoprotein mobility on HIV-1 particles depends on the virus maturation state

Nature communications, 2017-09, Vol.8 (1), p.545-10, Article 545

2017

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Prolonged viral suppression with anti-HIV-1 antibody therapy

Nature (London), 2022-06, Vol.606 (7913), p.368-374

2022

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Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

Nature (London), 2012-07, Vol.487 (7408), p.482-485

2012

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Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus

Scientific reports, 2013-08, Vol.3 (1), p.2510-2510, Article 2510

2013

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HIV-1 Gag co-localizes with euchromatin histone marks at the nuclear periphery

Journal of virology, 2023-12, Vol.97 (12), p.e0117923

2023

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IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation

Persistent HIV-1 replication maintains the tissue reservoir during therapy

Reactivation capacity by latency-reversing agents ex vivo correlates with the size of the HIV-1 reservoir

The Biology of the HIV-1 Latent Reservoir and Implications for Cure Strategies

SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef

HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis

CG dinucleotide suppression enables antiviral defence targeting non-self RNA

HIV: Shock and kill

Acetylation of Cytidine Residues Boosts HIV-1 Gene Expression by Increasing Viral RNA Stability

Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations

Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

HIV therapy by a combination of broadly neutralizing antibodies in humanized mice

A humanized mouse-based HIV-1 viral outgrowth assay with higher sensitivity than in vitro qVOA in detecting latently infected cells from individuals on ART with undetectable viral loads

CRISPR/Cas9-Derived Mutations Both Inhibit HIV-1 Replication and Accelerate Viral Escape

HIV-1 Pol Gene Polymorphism and Antiretroviral Resistance Mutations in Treatment-Naive Adult Patients in French Guiana Between 2006 and 2012

HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption

Clinical targeting of HIV capsid protein with a long-acting small molecule

N(6)-methyladenosine of HIV-1 RNA regulates viral infection and HIV-1 Gag protein expression

HIV-1 Integrase Binds the Viral RNA Genome and Is Essential during Virion Morphogenesis

Relationship between intact HIV-1 proviruses in circulating CD4⁺ T cells and rebound viruses emerging during treatment interruption

Envelope glycoprotein mobility on HIV-1 particles depends on the virus maturation state

Prolonged viral suppression with anti-HIV-1 antibody therapy

Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus

HIV-1 Gag co-localizes with euchromatin histone marks at the nuclear periphery

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