UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 6.852

Sortiert nach

HIV-1 Pol Gene Polymorphism and Antiretroviral Resistance Mutations in Treatment-Naive Adult Patients in French Guiana Between 2006 and 2012

AIDS research and human retroviruses, 2016-08, Vol.32 (8), p.801

2016

Link zum Volltext

Verfügbarkeit prüfen

Horizontal gene transfer from human host to HIV-1 reverse transcriptase confers drug resistance and partly compensates for replication deficits

Virology (New York, N.Y.), 2014-05, Vol.456, p.310-318

2014

Link zum Volltext

Verfügbarkeit prüfen

Reduced efficacy of HIV-1 integrase inhibitors in patients with drug resistance mutations in reverse transcriptase

Nature communications, 2020-12, Vol.11 (1), p.5922-5922, Article 5922

2020

Link zum Volltext

Verfügbarkeit prüfen

Exploiting the Tolerant Region I of the Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) Binding Pocket: Discovery of Potent Diarylpyrimidine-Typed HIV‑1 NNRTIs against Wild-Type and E138K Mutant Virus with Significantly Improved Water Solubility and Favorable Safety Profiles

Journal of medicinal chemistry, 2019-02, Vol.62 (4), p.2083-2098

2019

Link zum Volltext

Verfügbarkeit prüfen

Geographic and temporal trends in the molecular epidemiology and genetic mechanisms of transmitted HIV-1 drug resistance: an individual-patient- and sequence-level meta-analysis

PLoS medicine, 2015-04, Vol.12 (4), p.e1001810-e1001810

2015

Link zum Volltext

Verfügbarkeit prüfen

Development of Novel Dihydrofuro[3,4‑d]pyrimidine Derivatives as HIV‑1 NNRTIs to Overcome the Highly Resistant Mutant Strains F227L/V106A and K103N/Y181C

Journal of medicinal chemistry, 2022-02, Vol.65 (3), p.2458-2470

2022

Link zum Volltext

Verfügbarkeit prüfen

Covalent inhibitors for eradication of drug-resistant HIV-1 reverse transcriptase: From design to protein crystallography

Proceedings of the National Academy of Sciences - PNAS, 2017-09, Vol.114 (36), p.9725-9730

2017

Link zum Volltext

Verfügbarkeit prüfen

Targeting the entrance channel of NNIBP: Discovery of diarylnicotinamide 1,4-disubstituted 1,2,3-triazoles as novel HIV-1 NNRTIs with high potency against wild-type and E138K mutant virus

European journal of medicinal chemistry, 2018-05, Vol.151, p.339-350

2018

Link zum Volltext

Verfügbarkeit prüfen

Human immunodeficiency virus 1 5'-leader mutations in plasma viruses before and after the development of reverse transcriptase inhibitor-resistance mutations

Journal of general virology, 2023-10, Vol.104 (10)

2023

Link zum Volltext

Verfügbarkeit prüfen

HIV-1 Protease, Reverse Transcriptase, and Integrase Variation

Journal of virology, 2016-07, Vol.90 (13), p.6058-6070

2016

Link zum Volltext

Verfügbarkeit prüfen

High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs

Nature communications, 2021-05, Vol.12 (1), p.2500-11, Article 2500

2021

Link zum Volltext

Verfügbarkeit prüfen

Evolution of a reverse transcriptase to map N 1 -methyladenosine in human messenger RNA

Nature methods, 2019-12, Vol.16 (12), p.1281

2019

Link zum Volltext

Verfügbarkeit prüfen

Comparison of an In Vitro Diagnostic Next-Generation Sequencing Assay with Sanger Sequencing for HIV-1 Genotypic Resistance Testing

Journal of clinical microbiology, 2018-06, Vol.56 (6)

2018

Link zum Volltext

Verfügbarkeit prüfen

Transmitted drug resistance, selection of resistance mutations and moderate antiretroviral efficacy in HIV-2: analysis of the HIV-2 Belgium and Luxembourg database

BMC infectious diseases, 2008-02, Vol.8 (1), p.21-21, Article 21

2008

Link zum Volltext

Verfügbarkeit prüfen

Doravirine Suppresses Common Nonnucleoside Reverse Transcriptase Inhibitor-Associated Mutants at Clinically Relevant Concentrations

Antimicrobial agents and chemotherapy, 2016-04, Vol.60 (4), p.2241-2247

2016

Link zum Volltext

Verfügbarkeit prüfen

Non-catalytic site HIV-1 integrase inhibitors disrupt core maturation and induce a reverse transcription block in target cells

PloS one, 2013-09, Vol.8 (9), p.e74163

2013

Link zum Volltext

Verfügbarkeit prüfen

Structure-Based Design and Discovery of Pyridyl-Bearing Fused Bicyclic HIV‑1 Inhibitors: Synthesis, Biological Characterization, and Molecular Modeling Studies

Journal of medicinal chemistry, 2021-09, Vol.64 (18), p.13604-13621

2021

Link zum Volltext

Verfügbarkeit prüfen

The High Genetic Barrier of EFdA/MK-8591 Stems from Strong Interactions with the Active Site of Drug-Resistant HIV-1 Reverse Transcriptase

Cell chemical biology, 2018-10, Vol.25 (10), p.1268-1278.e3

2018

Link zum Volltext

Verfügbarkeit prüfen

Synthesis and Biological Evaluation of Aryl-phospho-indole as Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors

Journal of medicinal chemistry, 2011-01, Vol.54 (1), p.392-395

2011

Link zum Volltext

Verfügbarkeit prüfen

Variable antiviral activity of islatravir against M184I/V mutant HIV-1 selected during antiretroviral therapy

Journal of antimicrobial chemotherapy, 2024-02, Vol.79 (2), p.370-374

2024

Link zum Volltext

Verfügbarkeit prüfen

Molecular dynamics and Monte Carlo simulations for protein–ligand binding and inhibitor design

Biochimica et biophysica acta, 2015-05, Vol.1850 (5), p.966-971

2015

Link zum Volltext

Verfügbarkeit prüfen

Characterization of mutation spectra with ultra-deep pyrosequencing: application to HIV-1 drug resistance

Genome Research, 2007-08, Vol.17 (8), p.1195-1201

2007

Link zum Volltext

Verfügbarkeit prüfen

Impact of HIV-1 Resistance-Associated Mutations on Susceptibility to Doravirine: Analysis of Real-World Clinical Isolates

Antimicrobial agents and chemotherapy, 2021-11, Vol.65 (12), p.e0121621-e0121621

2021

Link zum Volltext

Verfügbarkeit prüfen

Small Conformational Changes Underlie Evolution of Resistance to NNRTI in HIV Reverse Transcriptase

Biophysical journal, 2020-05, Vol.118 (10), p.2489-2501

2020

Link zum Volltext

Verfügbarkeit prüfen

1 – 25 von 6.852

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(6.500)
Mit Volltextzugriff
(5.654)

Publikationsform

1 weiteren anzeigen...

Weniger anzeigen...

Sprache

8 weitere anzeigen...

Weniger anzeigen...

Erscheinungsjahr

n.n

Thema

Science & Technology
(5.930)
Humans
(5.644)
Life Sciences & Biomedicine
(5.493)
Hiv-1 - Genetics
(3.584)
Biological And Medical Sciences
(2.729)
Infectious Diseases
(2.723)
Virology
(2.613)
Aids/hiv
(2.593)
Hiv Infections - Drug Therapy
(2.494)
Hiv-1 - Drug Effects
(2.427)
Mutation
(2.323)
Human Immunodeficiency Virus 1
(2.288)
Medical Sciences
(2.266)
Hiv Reverse Transcriptase - Genetics
(2.249)
Hiv Infections - Virology
(2.237)
Female
(1.989)
Hiv
(1.972)
Human Immunodeficiency Virus
(1.970)
Male
(1.957)
Immunology
(1.814)

15 weitere anzeigen...

Weniger anzeigen...

Kollektion

15 weitere anzeigen...

Weniger anzeigen...

Zeitschrift / Serie

Aids
(453)
Aids Research And Human Retroviruses
(407)
Journal Of Virology
(327)
Journal Of Acquired Immune Deficiency Syndromes
(243)
Antimicrobial Agents And Chemotherapy
(239)
Plos One
(233)
Antiviral Therapy
(215)
The Journal Of Biological Chemistry
(204)
The Journal Of Infectious Diseases
(202)
Journal Of Medical Virology
(150)

5 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

... seit 30 Tagen
(1)
... seit 90 Tagen
(6)

Menü

Weitere Dienste

Einstellungen

HIV-1 Pol Gene Polymorphism and Antiretroviral Resistance Mutations in Treatment-Naive Adult Patients in French Guiana Between 2006 and 2012

Horizontal gene transfer from human host to HIV-1 reverse transcriptase confers drug resistance and partly compensates for replication deficits

Reduced efficacy of HIV-1 integrase inhibitors in patients with drug resistance mutations in reverse transcriptase

Exploiting the Tolerant Region I of the Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) Binding Pocket: Discovery of Potent Diarylpyrimidine-Typed HIV‑1 NNRTIs against Wild-Type and E138K Mutant Virus with Significantly Improved Water Solubility and Favorable Safety Profiles

Geographic and temporal trends in the molecular epidemiology and genetic mechanisms of transmitted HIV-1 drug resistance: an individual-patient- and sequence-level meta-analysis

Development of Novel Dihydrofuro[3,4‑d]pyrimidine Derivatives as HIV‑1 NNRTIs to Overcome the Highly Resistant Mutant Strains F227L/V106A and K103N/Y181C

Covalent inhibitors for eradication of drug-resistant HIV-1 reverse transcriptase: From design to protein crystallography

Targeting the entrance channel of NNIBP: Discovery of diarylnicotinamide 1,4-disubstituted 1,2,3-triazoles as novel HIV-1 NNRTIs with high potency against wild-type and E138K mutant virus

Human immunodeficiency virus 1 5'-leader mutations in plasma viruses before and after the development of reverse transcriptase inhibitor-resistance mutations

HIV-1 Protease, Reverse Transcriptase, and Integrase Variation

High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs

Evolution of a reverse transcriptase to map N 1 -methyladenosine in human messenger RNA

Comparison of an In Vitro Diagnostic Next-Generation Sequencing Assay with Sanger Sequencing for HIV-1 Genotypic Resistance Testing

Prevalence and epidemiology of HIV type 1 drug resistance among newly diagnosed therapy-naive patients in Belgium from 2003 to 2006

Transmitted drug resistance, selection of resistance mutations and moderate antiretroviral efficacy in HIV-2: analysis of the HIV-2 Belgium and Luxembourg database

Doravirine Suppresses Common Nonnucleoside Reverse Transcriptase Inhibitor-Associated Mutants at Clinically Relevant Concentrations

Non-catalytic site HIV-1 integrase inhibitors disrupt core maturation and induce a reverse transcription block in target cells

Structure-Based Design and Discovery of Pyridyl-Bearing Fused Bicyclic HIV‑1 Inhibitors: Synthesis, Biological Characterization, and Molecular Modeling Studies

The High Genetic Barrier of EFdA/MK-8591 Stems from Strong Interactions with the Active Site of Drug-Resistant HIV-1 Reverse Transcriptase

Synthesis and Biological Evaluation of Aryl-phospho-indole as Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors

Variable antiviral activity of islatravir against M184I/V mutant HIV-1 selected during antiretroviral therapy

Molecular dynamics and Monte Carlo simulations for protein–ligand binding and inhibitor design

Characterization of mutation spectra with ultra-deep pyrosequencing: application to HIV-1 drug resistance

Impact of HIV-1 Resistance-Associated Mutations on Susceptibility to Doravirine: Analysis of Real-World Clinical Isolates

Small Conformational Changes Underlie Evolution of Resistance to NNRTI in HIV Reverse Transcriptase

Suchergebnisse filtern