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Abstract 1180 Structural investigations of Mus musculus ATE1

The Journal of biological chemistry, 2024-03, Vol.300 (3), p.106840, Article 106840

Cartwright, Misti

2024

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Bridging protein structure, dynamics, and function using hydrogen/deuterium‐exchange mass spectrometry

Protein science, 2020-04, Vol.29 (4), p.843-855

2020

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Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains

Immunity (Cambridge, Mass.), 2021-10, Vol.54 (10), p.2218-2230.e5

2021

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Hydrogen-Deuterium Exchange Coupled to Top- and Middle-Down Mass Spectrometry Reveals Histone Tail Dynamics before and after Nucleosome Assembly

Structure (London), 2018-12, Vol.26 (12), p.1651-1663.e3

2018

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USP28 and USP25 are downregulated by Vismodegib in vitro and in colorectal cancer cell lines

The FEBS journal, 2021-02, Vol.288 (4), p.1325-1342

2021

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An overview of hydrogen deuterium exchange mass spectrometry (HDX-MS) in drug discovery

Expert opinion on drug discovery, 2017-10, Vol.12 (10), p.981-994

2017

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Conformational disruption of PI3Kδ regulation by immunodeficiency mutations in PIK3CD and PIK3R1

Proceedings of the National Academy of Sciences - PNAS, 2017-02, Vol.114 (8), p.1982-1987

2017

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From haemadin to haemanorm: Synthesis and characterization of full‐length haemadin from the leech Haemadipsa sylvestris and of a novel bivalent, highly potent thrombin inhibitor (haemanorm)

Protein science, 2023-12, Vol.32 (12), p.e4825-n/a

2023

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Rapid label-free cell-based Approach Membrane Permeability Assay using MALDI-hydrogen-deuterium exchange mass spectrometry for peptides

Analytica chimica acta, 2022-09, Vol.1225, p.340234-340234, Article 340234

2022

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Phospho‐regulation, nucleotide binding and ion access control in potassium‐chloride cotransporters

The EMBO journal, 2021-07, Vol.40 (14), p.e107294-n/a

2021

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Investigation of D76N β2‑Microglobulin Using Protein Footprinting and Structural Mass Spectrometry

Journal of the American Society for Mass Spectrometry, 2021-07, Vol.32 (7), p.1583-1592

2021

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Evolutionary adaptation of the protein folding pathway for secretability

The EMBO journal, 2022-12, Vol.41 (23), p.e111344-n/a

2022

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Protein structure prediction using residue-resolved protection factors from hydrogen-deuterium exchange NMR

Structure (London), 2022-02, Vol.30 (2), p.313-320.e3

2022

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Conformational analysis of complex protein states by hydrogen/deuterium exchange mass spectrometry (HDX-MS): Challenges and emerging solutions

TrAC, Trends in analytical chemistry (Regular ed.), 2018-09, Vol.106, p.125-138

2018

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The intrinsic instability of the hydrolase domain of lipoprotein lipase facilitates its inactivation by ANGPTL4-catalyzed unfolding

Proceedings of the National Academy of Sciences - PNAS, 2021-03, Vol.118 (12)

2021

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Analysis of Translocation-Competent Secretory Proteins by HDX-MS

Methods in enzymology, 2017, Vol.586, p.57-83

2017

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High‐resolution analysis of the conformational transition of pro‐apoptotic Bak at the lipid membrane

The EMBO journal, 2021-10, Vol.40 (20), p.e107159-n/a

2021

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Irisin acts through its integrin receptor in a two-step process involving extracellular Hsp90α

Molecular cell, 2023-06, Vol.83 (11), p.1903-1920.e12

2023

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Characterization of the c10orf76‐PI4KB complex and its necessity for Golgi PI4P levels and enterovirus replication

EMBO reports, 2020-02, Vol.21 (2), p.e48441-n/a

2020

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A current structural perspective on PXR and CAR in drug metabolism

Expert opinion on drug metabolism & toxicology, 2018-06, Vol.14 (6), p.635-647

2018

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Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor

Cell, 2019-06, Vol.177 (7), p.1725-1737.e16

2019

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3,4‐Dihydroxyphenylethanol and 3,4‐dihydroxyphenylacetic acid affect the aggregation process of E46K variant of α‐synuclein at different extent: Insights into the interplay between protein dynamics and catechol effect

Protein science, 2022-07, Vol.31 (7), p.e4356-n/a

2022

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Activation of GCN2 by the ribosomal P-stalk

Proceedings of the National Academy of Sciences - PNAS, 2019-03, Vol.116 (11), p.4946-4954

2019

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Impact of C‐terminal truncations in the Arabidopsis Rab escort protein (REP) on REP–Rab interaction and plant fertility

The Plant journal : for cell and molecular biology, 2021-12, Vol.108 (5), p.1400-1421

2021

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Preferred inhibition of pro-apoptotic Bak by BclxL via a two-step mechanism

Cell reports (Cambridge), 2024-08, Vol.43 (8), p.114526, Article 114526

2024

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Abstract 1180 Structural investigations of Mus musculus ATE1

Bridging protein structure, dynamics, and function using hydrogen/deuterium‐exchange mass spectrometry

Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains

Hydrogen-Deuterium Exchange Coupled to Top- and Middle-Down Mass Spectrometry Reveals Histone Tail Dynamics before and after Nucleosome Assembly

USP28 and USP25 are downregulated by Vismodegib in vitro and in colorectal cancer cell lines

An overview of hydrogen deuterium exchange mass spectrometry (HDX-MS) in drug discovery

Conformational disruption of PI3Kδ regulation by immunodeficiency mutations in PIK3CD and PIK3R1

From haemadin to haemanorm: Synthesis and characterization of full‐length haemadin from the leech Haemadipsa sylvestris and of a novel bivalent, highly potent thrombin inhibitor (haemanorm)

Rapid label-free cell-based Approach Membrane Permeability Assay using MALDI-hydrogen-deuterium exchange mass spectrometry for peptides

Phospho‐regulation, nucleotide binding and ion access control in potassium‐chloride cotransporters

Investigation of D76N β2‑Microglobulin Using Protein Footprinting and Structural Mass Spectrometry

Evolutionary adaptation of the protein folding pathway for secretability

Protein structure prediction using residue-resolved protection factors from hydrogen-deuterium exchange NMR

Conformational analysis of complex protein states by hydrogen/deuterium exchange mass spectrometry (HDX-MS): Challenges and emerging solutions

The intrinsic instability of the hydrolase domain of lipoprotein lipase facilitates its inactivation by ANGPTL4-catalyzed unfolding

Analysis of Translocation-Competent Secretory Proteins by HDX-MS

High‐resolution analysis of the conformational transition of pro‐apoptotic Bak at the lipid membrane

Irisin acts through its integrin receptor in a two-step process involving extracellular Hsp90α

Characterization of the c10orf76‐PI4KB complex and its necessity for Golgi PI4P levels and enterovirus replication

A current structural perspective on PXR and CAR in drug metabolism

Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor

3,4‐Dihydroxyphenylethanol and 3,4‐dihydroxyphenylacetic acid affect the aggregation process of E46K variant of α‐synuclein at different extent: Insights into the interplay between protein dynamics and catechol effect

Activation of GCN2 by the ribosomal P-stalk

Impact of C‐terminal truncations in the Arabidopsis Rab escort protein (REP) on REP–Rab interaction and plant fertility

Preferred inhibition of pro-apoptotic Bak by BclxL via a two-step mechanism

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