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Metabolism of doxorubicin to the cardiotoxic metabolite doxorubicinol is increased in a mouse model of chronic glutathione deficiency: A potential role for carbonyl reductase 3

Chemico-biological interactions, 2015-06, Vol.234, p.154-161

2015

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SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells

Nature (London), 2021-11, Vol.599 (7883), p.136-140

2021

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Glutathione is essential for early embryogenesis – Analysis of a glutathione synthetase knockout mouse

Biochemical and biophysical research communications, 2011-08, Vol.412 (1), p.121-126

2011

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Endogenous Deficiency of Glutathione as the Most Likely Cause of Serious Manifestations and Death in COVID-19 Patients

ACS infectious diseases, 2020-07, Vol.6 (7), p.1558-1562

Polonikov, Alexey

2020

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Glutathione deficiency induces epigenetic alterations of vitamin D metabolism genes in the livers of high-fat diet-fed obese mice

Scientific reports, 2019-10, Vol.9 (1), p.14784-11, Article 14784

2019

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Ferroptosis Mediates Cuprizone-Induced Loss of Oligodendrocytes and Demyelination

The Journal of neuroscience, 2020-11, Vol.40 (48), p.9327-9341

2020

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Bilirubin and glutathione have complementary antioxidant and cytoprotective roles

Proceedings of the National Academy of Sciences - PNAS, 2009-03, Vol.106 (13), p.5171-5176

2009

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Fostered Nrf2 expression antagonizes iron overload and glutathione depletion to promote resistance of neuron-like cells to ferroptosis

Toxicology and applied pharmacology, 2020-11, Vol.407, p.115241, Article 115241

2020

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Glutathione defense mechanism in liver injury: Insights from animal models

Food and chemical toxicology, 2013-10, Vol.60, p.38-44

2013

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Oxidative stress in early cystic fibrosis lung disease is exacerbated by airway glutathione deficiency

Free radical biology & medicine, 2017-12, Vol.113, p.236-243

2017

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Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation

The American journal of clinical nutrition, 2011-09, Vol.94 (3), p.847-853

2011

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Five Chinese patients with 5-oxoprolinuria due to glutathione synthetase and 5-oxoprolinase deficiencies

Brain & development (Tokyo. 1979), 2015-11, Vol.37 (10), p.952-959

2015

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System x(c)- and thioredoxin reductase 1 cooperatively rescue glutathione deficiency

The Journal of biological chemistry, 2010-07, Vol.285 (29), p.22244

2010

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Preparation of a γ-glutamylcysteine-enriched yeast extract from a newly developed GSH2-deficient strain

Journal of bioscience and bioengineering, 2013-01, Vol.115 (1), p.50-54

2013

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Impaired glutathione synthesis in schizophrenia: Convergent genetic and functional evidence

Proceedings of the National Academy of Sciences - PNAS, 2007-10, Vol.104 (42), p.16621-16626

2007

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Antioxidants, redox signaling, and pathophysiology in schizophrenia: an integrative view

Antioxidants & redox signaling, 2011-10, Vol.15 (7), p.2011

2011

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Analysis of glutathione: implication in redox and detoxification

Clinica Chimica Acta, 2003-07, Vol.333 (1), p.19-39

2003

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Inhibition of bacterial thioredoxin reductase: an antibiotic mechanism targeting bacteria lacking glutathione

The FASEB journal, 2013-04, Vol.27 (4), p.1394-1403

2013

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Contribution of impaired Nrf2-Keap1 pathway to oxidative stress and inflammation in chronic renal failure

American journal of physiology. Renal physiology, 2010-03, Vol.298 (3), p.F662-F671

2010

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An updating meta-analysis of the GSTM1, GSTT1, and GSTP1 polymorphisms and prostate cancer: A HuGE Review

The Prostate, 2009-05, Vol.69 (6), p.662-688

2009

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The central role of glutathione in the pathophysiology of human diseases

Archives of physiology and biochemistry, 2007-10, Vol.113 (4-5), p.234-258

2007

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A Rare Cause of Neonatal Hemolytic Anemia: Glutathione Synthetase Deficiency

Journal of pediatric hematology/oncology, 2018-01, Vol.40 (1), p.e45-e49

2018

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Clinical findings and effect of sodium hydrogen carbonate in patients with glutathione synthetase deficiency

Journal of pediatric endocrinology & metabolism : JPEM, 2016-04, Vol.29 (4), p.481

2016

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Glutathione peroxidase 1-deficient mice are more susceptible to doxorubicin-induced cardiotoxicity

Biochimica et biophysica acta, 2008-10, Vol.1783 (10), p.2020-2029

2008

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ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

Nature chemical biology, 2017-01, Vol.13 (1), p.91

2017

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